An Assessment of Fate of CHA Blocks Used in the Cystic Lesions of Bone.
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Date
2016-01
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Abstract
Background: The calcium phosphate system and in particular hydroxyapatite (CHA), has been the subject of intensive
investigation. Although coralline hydroxyapatite is not inherently as strong as trabecular bone and does not exhibit plastic
properties owing to the absence of a collagen matrix, with subsequent growth of native bone, it has been shown to become
stronger but less stiff than autogenous graft material. Method: Thirty six cases of cystic lesions of long bones were
curretted and filled with CHA blocks with or without autogenous cancellous bone chips between 2013 to 2014 with follow
up duration ranging from 12 to 24 months. Filling by CHA blocks, mixing with autogenous bone grafts was done in
osteoclastoma and fibrous dysplasia cases, while only CHA block filling was done in solitary bone cyst, aneurysmal bone
cyst and fibroma cases. In all the cases, the diagnosis was made on the basis of clinical, radiological and histopathological
examination. Both with and without pathological fractures cystic lesions were taken. Results: In the present study, 11
cases had pathological fracture. In our series, maximum cases were of osteoclastoma. Most of the cases were associated
with pathological fracture. The pathological fractures united from 20-30 weeks time, Radiologically, the density of CHA
blocks increased with the lapse of time. In our series, the longest follow up period was about 24 months and the shortest
was of 12 months duration. 20 patients had excellent results with full functional, anatomical restoration without any pain
and radiograph shows no recurrence, with healing of pathological fracture. While 2 patients had poor results they were
not able to do activities of daily living, had pain and delayed healing. Conclusion: The CHA has favourable clinical result
because of less adverse effects, biocompatibility to the tissue of the body, ease of manufacture, production and shape
adjustment. Therefore, it is strongly suggested as a useful bone substitute.In our limited experience with coralline
hydroxyapatite bone graft substitutes, we have encountered no significant complications related to implant themselves.
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Keywords
Calcium Hydroxyapatite, Tumours-Cystic lesions of bone (Osteoclastoma, Fibrous Dysplasia, Solitary bone cyst, Aneuysmal bone cyst, Fibroma).
Citation
Sharma Pervaind, Iqbal Asif, Huda Najmul, Pant Ajay. An Assessment of Fate of CHA Blocks Used in the Cystic Lesions of Bone. Annals of International Medical and Dental Research. 2016 Jan-Feb; 2(1): 306-310.