Profile of exudative pleural effusion in the region of Bhuj people

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dc.contributor.authorDesai, Vishal K.en_US
dc.contributor.authorArora, Rashmi S.en_US
dc.date.accessioned2020-04-09T07:40:01Z
dc.date.available2020-04-09T07:40:01Z
dc.date.issued2018-07
dc.description.abstractBackground: Exudative pleural effusions are a common diagnostic problem in clinical practice, as the list of causes is quite exhaustive, although sometimes they can be inferred from the clinical picture. In the West the most common cause is Para pneumonic effusions followed by malignancy, while in India it is tubercular effusion followed by malignant effusion. Despite the availability of various tests, there is a need for defining the best diagnostic and cost-effective approach to quickly diagnose and treat exudative pleural effusions. The objectives are to conduct a clinical and etiological study of exudative pleural effusion, to evaluate biochemical profile, cytological profile and radiological profiles of exudative pleural effusion.Methods: Prospective study of 100 patients with exudative pleural effusions. The demographic data was expressed as mean±standard deviation. Comparison between groups was done by Chi-Square test and Fischer exact test for categorical variables and Kruskar-Wallis and Mann-Whitney tests for continuous variables.Results: There were 67 males and 33 females. The mean age was 41.6±15.74. The majority were tubercular in origin (67%),13%,8%,3%and 6% were malignant effusions, Synpneumonic effusion, pancreatic effusions and empyema respectively. Diagnosis was not established in 3% of effusions. Massive effusions were seen in 53.8% of malignant effusions and 33.3% of empyemas. Most effusions had a total cell count between 1000 to 5000 cells /mm3.Lymphocyte predominant effusions were seen in 84.6% and 89.6% of malignant and tubercular effusions. 61.5% of malignant effusions had a positive cytology. Tubercular effusion had a pleural fluid ADA more than 40 IU/L. 92.3% of malignant effusion had pleural fluid ADA less than 30IU.Conclusions: Pleural effusion is a commonly encountered in medical practice and in our country, the commonest cause is tuberculosis, as is evidenced from the present study. The initial step in evaluating case of pleural effusion is to establish the cause of pleural effusion which is done by a detailed history, clinical examination and investigations like a chest radiology and pleural fluid analysis. Even in the advanced diagnostic approaches, still detailed clinical history and examination of the patient of the patient is important to make a clinical diagnosis. All suspected cases of pleural effusion should undergo Sonography of the thorax along with routine chest x-ray. Fluid cytology should be done to confirm tuberculosis or to rule out malignancy, which guides the physician for further evaluation of the patient if required.en_US
dc.identifier.affiliationsDepartment of Medicine, GAIMS, Bhuj, Gujarat, Indiaen_US
dc.identifier.affiliationsDepartment of Dermatology and Venerology, Jiya Hospital, Bhuj-Kutch, Gujarat, Indiaen_US
dc.identifier.citationDesai Vishal K., Arora Rashmi S.. Profile of exudative pleural effusion in the region of Bhuj people. International Journal of Advances in Medicine. 2018 Jul; 5(4): 1057-1064en_US
dc.identifier.issn2349-3925
dc.identifier.issn2349-3933
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/193967
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber4en_US
dc.relation.volume5en_US
dc.source.urihttps://dx.doi.org/10.18203/2349-3933.ijam20183147en_US
dc.subjectEmpyemaen_US
dc.subjectPleural effusionen_US
dc.subjectTuberculosisen_US
dc.titleProfile of exudative pleural effusion in the region of Bhuj peopleen_US
dc.typeJournal Articleen_US
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