Evaluation of iron status: zinc protoporphyrin vis-a-vis bone marrow iron stores.

dc.contributor.authorDas, Sheilaen_US
dc.contributor.authorPhilip, Kandathil Josephen_US
dc.date.accessioned2008-01-18en_US
dc.date.accessioned2009-05-29T12:34:06Z
dc.date.available2008-01-18en_US
dc.date.available2009-05-29T12:34:06Z
dc.date.issued2008-01-18en_US
dc.description.abstractZinc protoporphyrin (ZPP) in the red cells is an indicator of iron status in the bone marrow (BM) and can be easily measured by Protofluor-Z Hematofluorometer from Helena Laboratories. It is well known that bone marrow iron is a gold standard for the diagnosis of iron deficiency anemia (IDA) even in the pre-latent phase. Hence, it was considered pertinent to evaluate the diagnostic utility of ZPP in comparison with bone marrow iron stores. 107 random BM were selected over a period of 2(1/2) years; in each case, RBC indices where recorded along with ZPP and Perls' Prussian blue reaction for BM iron stores. The specificity and sensitivity were found to be 77.8% and sensitivity 69.8%, respectively. However, the sensitivity increased up to 96.2% when Hb, RBC indices and ZPP were considered for the diagnosis of IDA.en_US
dc.description.affiliationDepartment Pathology, Christian Medical College, Ludhiana, India. dasskus@yahoo.com.en_US
dc.identifier.citationDas S, Philip KJ. Evaluation of iron status: zinc protoporphyrin vis-a-vis bone marrow iron stores. Indian Journal of Pathology & Microbiology. 2008 Jan-Mar; 51(1): 105-7en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/74728
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.subject.meshAnemia, Iron-Deficiency --diagnosisen_US
dc.subject.meshBone Marrow --chemistryen_US
dc.subject.meshHumansen_US
dc.subject.meshIron --analysisen_US
dc.subject.meshProtoporphyrins --blooden_US
dc.subject.meshSensitivity and Specificityen_US
dc.titleEvaluation of iron status: zinc protoporphyrin vis-a-vis bone marrow iron stores.en_US
dc.typeEvaluation Studiesen_US
dc.typeJournal Articleen_US
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