Evaluation of iron status: zinc protoporphyrin vis-a-vis bone marrow iron stores.
dc.contributor.author | Das, Sheila | en_US |
dc.contributor.author | Philip, Kandathil Joseph | en_US |
dc.date.accessioned | 2008-01-18 | en_US |
dc.date.accessioned | 2009-05-29T12:34:06Z | |
dc.date.available | 2008-01-18 | en_US |
dc.date.available | 2009-05-29T12:34:06Z | |
dc.date.issued | 2008-01-18 | en_US |
dc.description.abstract | Zinc protoporphyrin (ZPP) in the red cells is an indicator of iron status in the bone marrow (BM) and can be easily measured by Protofluor-Z Hematofluorometer from Helena Laboratories. It is well known that bone marrow iron is a gold standard for the diagnosis of iron deficiency anemia (IDA) even in the pre-latent phase. Hence, it was considered pertinent to evaluate the diagnostic utility of ZPP in comparison with bone marrow iron stores. 107 random BM were selected over a period of 2(1/2) years; in each case, RBC indices where recorded along with ZPP and Perls' Prussian blue reaction for BM iron stores. The specificity and sensitivity were found to be 77.8% and sensitivity 69.8%, respectively. However, the sensitivity increased up to 96.2% when Hb, RBC indices and ZPP were considered for the diagnosis of IDA. | en_US |
dc.description.affiliation | Department Pathology, Christian Medical College, Ludhiana, India. dasskus@yahoo.com. | en_US |
dc.identifier.citation | Das S, Philip KJ. Evaluation of iron status: zinc protoporphyrin vis-a-vis bone marrow iron stores. Indian Journal of Pathology & Microbiology. 2008 Jan-Mar; 51(1): 105-7 | en_US |
dc.identifier.uri | https://imsear.searo.who.int/handle/123456789/74728 | |
dc.language.iso | eng | en_US |
dc.source.uri | https://www.ijpmonline.org | en_US |
dc.subject.mesh | Anemia, Iron-Deficiency --diagnosis | en_US |
dc.subject.mesh | Bone Marrow --chemistry | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Iron --analysis | en_US |
dc.subject.mesh | Protoporphyrins --blood | en_US |
dc.subject.mesh | Sensitivity and Specificity | en_US |
dc.title | Evaluation of iron status: zinc protoporphyrin vis-a-vis bone marrow iron stores. | en_US |
dc.type | Evaluation Studies | en_US |
dc.type | Journal Article | en_US |
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