Hypofractionated radiotherapy in carcinoma cervix IIIB: Tata Memorial Hospital experience.

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dc.contributor.authorMuckaden, M Aen_US
dc.contributor.authorBudrukkar, A Nen_US
dc.contributor.authorTongaonkar, H Ben_US
dc.contributor.authorDinshaw, K Aen_US
dc.date.accessioned2009-05-28T06:27:22Z
dc.date.available2009-05-28T06:27:22Z
dc.date.issued2002-10-21en_US
dc.description.abstractPURPOSE OF THE STUDY: To analyze the role of hypofractionated radiotherapy in advanced carcinoma of cervix. BASIC PROCEDURE: Medical records of 62 women with advanced carcinoma cervix III3 treated during 1994-1996 were reviewed. Patients were treated with standard pelvic portals to a total dose of 39Gy in 13 fractions over 17 days followed by intracavitary brachytherapy. Forty-eight patients completed the planned treatment and were considered suitable for analysis of late reactions and survival. MAIN FINDINGS: The 5-year disease free survival was 59% and the overall survival was 50% at the mean follow up of 40 months. Twenty-one (44%) patients developed acute gastrointestinal toxicity of which 5 patients had grade III and one patient had grade IV reaction. Ten patients (21%) developed acute genitourinary complications, 13 patients (27%) had late rectal reactions and 10 patients (20%) had late bladder complications. Three patients had grade I, five had grade II and five had grade III late rectal toxicity. CONCLUSION: Survival in patients treated hypofractionated radiotherapy appears comparable to that of standard fractionation. The acute gastrointestinal and skin reactions were mainly grade I or grade II. Hypofractionated radiotherapy can certainly be considered in a select group of patients where the local disease is extensive and is unsuitable for conventional treatment.en_US
dc.description.affiliationDept. of Radiation Oncology, Tata Memorial Hospital, Mumbai 400 012, Maharashtra, India.en_US
dc.identifier.citationMuckaden MA, Budrukkar AN, Tongaonkar HB, Dinshaw KA. Hypofractionated radiotherapy in carcinoma cervix IIIB: Tata Memorial Hospital experience. Indian Journal of Cancer. 2002 Oct-Dec; 39(4): 127-34en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/49866
dc.language.isoengen_US
dc.source.urihttps://www.indianjcancer.comen_US
dc.subject.meshAdenocarcinoma --pathologyen_US
dc.subject.meshAdulten_US
dc.subject.meshDose Fractionationen_US
dc.subject.meshFemaleen_US
dc.subject.meshHospitalsen_US
dc.subject.meshHumansen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshNeoplasm Stagingen_US
dc.subject.meshRadiotherapy Dosageen_US
dc.subject.meshSurvival Rateen_US
dc.subject.meshUterine Cervical Neoplasms --pathologyen_US
dc.titleHypofractionated radiotherapy in carcinoma cervix IIIB: Tata Memorial Hospital experience.en_US
dc.typeJournal Articleen_US
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