Aggressive behaviour of solid arrangement pattern in differentiated papillary carcinoma of thyroid.

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dc.contributor.authorBasu, Sen_US
dc.contributor.authorNair, Nen_US
dc.contributor.authorBorges, Anita Men_US
dc.date.accessioned2003-04-02en_US
dc.date.accessioned2009-05-31T02:15:05Z
dc.date.available2003-04-02en_US
dc.date.available2009-05-31T02:15:05Z
dc.date.issued2003-04-02en_US
dc.description.abstractThe prognosis and overall outcome of solid growth pattern in differentiated papillary carcinoma of thyroid is controversial. While general consensus suggest outcomes similar to typical papillary carcinomas others demonstrate a more aggressive biology. We present a case of differentiated papillary carcinoma of thyroid with solid growth pattern presenting with neck swelling and widespread skeletal metastases. The areas of bone lesions showed avid 131I concentration on a postoperative large dose 131I whole body scan and was treated with 131I subsequently. The present case suggest that the solid architecture in a papillary thyroid carcinoma may be indicative of an aggressive clinical course, contrary to the common opinion that it does not adversely influence its biologic behaviour and thus emphasize the need to reexplore the prognostic significance of histopathologic subclassification along with an assessment of histologic grade and expression of molecular risk factors in this particular tumour subtype.en_US
dc.description.affiliationRadiation Medicine Centre, Tata Memorial Hospital, Jerbai Wadia Road, Parel, Mumbai 400 012.en_US
dc.identifier.citationBasu S, Nair N, Borges AM. Aggressive behaviour of solid arrangement pattern in differentiated papillary carcinoma of thyroid. Journal of the Association of Physicians of India. 2003 Apr; 51(): 408-11en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/92880
dc.language.isoengen_US
dc.source.urihttps://www.japi.orgen_US
dc.subject.meshAdenocarcinoma --diagnosisen_US
dc.subject.meshAdulten_US
dc.subject.meshCarcinoma, Papillary --diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshIndiaen_US
dc.subject.meshMaleen_US
dc.subject.meshPrognosisen_US
dc.subject.meshThyroid Neoplasms --diagnosisen_US
dc.titleAggressive behaviour of solid arrangement pattern in differentiated papillary carcinoma of thyroid.en_US
dc.typeCase Reportsen_US
dc.typeJournal Articleen_US
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