Acinetobacter sepsis in newborns.

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dc.contributor.authorMishra, Aen_US
dc.contributor.authorMishra, Sen_US
dc.contributor.authorJaganath, Gen_US
dc.contributor.authorMittal, R Ken_US
dc.contributor.authorGupta, P Ken_US
dc.contributor.authorPatra, D Pen_US
dc.date.accessioned1998-01-26en_US
dc.date.accessioned2009-05-27T05:18:37Z
dc.date.available1998-01-26en_US
dc.date.available2009-05-27T05:18:37Z
dc.date.issued1998-01-26en_US
dc.description.abstractOBJECTIVE: To evaluate the clinico-epidemiological profile of Acinetobacter sepsis in neonates. DESIGN: Retrospective study. SETTING: Level II Neonatal Care Unit. SUBJECTS: 79 neonates with blood culture positive for Acinetobacter. METHODS: Relevant information was collected on a predesigned proforma from the case records and analyzed for clinical and epidemiological characteristics. RESULTS: The incidence of Acinetobacter septicemia was 11.1/1000 live births. Fifty-five babies were hospital born, 24 were outborn. Out of these, 64.6% babies were born at term and 40.5% had a birth weight of 2500 g or more. A cluster of 53 cases was seen between May and September 1995. In cases with early onset sepsis (onset < 7 days of postnatal age), difficulty in breathing (n = 54), chest retraction (n = 35) and refusal to feed (n = 46) were seen more commonly as compared to late onset sepsis (p < 0.05). Complications observed included meningitis, bleeding manifestations and necrotising enterocolitis in three, six and five babies, respectively. The organism was sensitive to ciprofloxacin (96.2%), amikacin (92.4%) and gentamicin (87.3%). A response rate of 52.4% was observed with Ciprofloxacin in babies not responding to cefotaxime and amikacin combination. The overall mortality was 13.9%. CONCLUSION: Nosocomial Acinetobacter sepsis may affect fullterm, appropriate for gestational age babies. Clinical presentation is indistinguishable from Gram negative septicemia. Life threatening complications can also occur. Ciprofloxacin may prove to be useful drug in resistant cases.en_US
dc.description.affiliationDepartment of Pediatrics, Tata Main Hospital, Jamshedpur.en_US
dc.identifier.citationMishra A, Mishra S, Jaganath G, Mittal RK, Gupta PK, Patra DP. Acinetobacter sepsis in newborns. Indian Pediatrics. 1998 Jan; 35(1): 27-32en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/9917
dc.language.isoengen_US
dc.source.urihttps://indianpediatrics.neten_US
dc.subject.meshAcinetobacter Infections --diagnosisen_US
dc.subject.meshHumansen_US
dc.subject.meshInfant, Newbornen_US
dc.subject.meshRetrospective Studiesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshSepsis --diagnosisen_US
dc.titleAcinetobacter sepsis in newborns.en_US
dc.typeJournal Articleen_US
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