The B-cell non-Hodgkin’s lymphoma: An enigma to diagnose

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Date
2023-07
Journal Title
Journal ISSN
Volume Title
Publisher
Mansa STM Publishers
Abstract
Non-Hodgkin’s lymphoma is a heterogeneous group of malignancies characterized by an abnormal clonal proliferation of T-cells, B-cells, or both. Sometimes, tuberculosis and lymphoma presentation can share common symptoms and features. In this case report, we present the case of a 28-year-old female patient who came with a chief complaint of swelling on the right side of the face for the past 6 months. Initially, it was not associated with pain but gradually developed severe pain over the region and reduced salivary flow. The patient was planned for surgery with a differential diagnosis of salivary gland pathology. Post-operatively, the histopathological report showed atypical cells which were diffusely positive for cluster of differentiation (CD)20. Focally positive for CD45 and CD3 which was positive in reactive T lymphocytes. Immunohistochemistry pattern favors the diagnosis of B-cell type NHL. Through this case report, we want to share our experience in treating an aggressive tumor that mimics salivary gland pathology.
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Keywords
B-cell variant, Cluster of differentiation 20, Fine needle aspiration cytology, Non-Hodgkin’s lymphoma
Citation
Iyer Shruti Suryanarayan, Narayanan Vivek, Ramakrishnan Karthik, Gurram Prashanthi, Subramanian Abinaya. The B-cell non-Hodgkin’s lymphoma: An enigma to diagnose. Indian Journal of Case Reports. 2023 July; 9(7): 198-200