Thailand diabetes registry project: prevalence of vascular complications in long-standing type 2 diabetes.

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dc.contributor.authorLeelawattana, Rattanaen_US
dc.contributor.authorPratipanawatr, Thongchaien_US
dc.contributor.authorBunnag, Pongamornen_US
dc.contributor.authorKosachunhanun, Natapongen_US
dc.contributor.authorSuwanwalaikorn, Sompongseen_US
dc.contributor.authorKrittiyawong, Sirinateen_US
dc.contributor.authorChetthakul, Thanyaen_US
dc.contributor.authorPlengvidhya, Nattacheten_US
dc.contributor.authorBenjasuratwong, Yupinen_US
dc.contributor.authorDeerochanawong, Chaicharnen_US
dc.contributor.authorMongkolsomlit, Sirimaen_US
dc.contributor.authorNgarmukos, Chardpraornen_US
dc.contributor.authorRawdaree, Petchen_US
dc.date.accessioned2009-05-27T20:54:24Z
dc.date.available2009-05-27T20:54:24Z
dc.date.issued2006-08-25en_US
dc.descriptionChotmaihet Thangphaet.en_US
dc.description.abstractOBJECTIVE: To explore the nature of diabetic complications in type 2 diabetic patients who had had diabetes for longer than 15 years (long-DM), compared to those with duration of less than 15 years (short-DM). MATERIAL AND METHOD: Patients studied were adult type 2 diabetic patients registered to the Diabetes Registry Project, a nationwide cross-sectional study of diabetes mellitus in Thailand. Information collected included demographic data, age at diagnosis of diabetes, blood pressure, body mass index, fasting plasma glucose, HbA(1c), serum creatinine, and major diabetic vascular complications, including diabetic retinopathy (DR), albuminuria or renal insufficiency (diabetic nephropathy; DN), myocardial infarction (MI), stroke, peripheral arterial disease (PAD), foot ulcer and amputation. RESULTS: There were 9284 patients, consisting of 2244 (24.17%) subjects with long-DM (mean +/- SD, mean duration of DM21.3 +/- 5.8 years), and 7040 subjects with short-DM (mean duration 7.0 +/- 3.9 years). The long-DM group was older than the short-DM group (65.5 +/- 10.3 vs. 58.2 +/- 12.6 year-old, p less than 0.0001), and had higher HbA(1c) (8.5 vs. 8.0%, p = 0.009). The prevalence of diabetic complications in the long-DM group was higher than that in the short-DM group (DN 49.4% vs. 33.9%, DR 54.3% vs. 22.8%; MI 9.4% vs. 3.5%, PAD 17.3% vs. 5.5%, foot ulcer 13.4% vs. 5.3%, stroke 9.4% vs. 7.0% and amputation 5.5% vs 2.0%; allp values less than 0.01). The duration of DM significantly affected the risk of diabetic complications after adjustment for age, hypertension, and levels of glycemic control. CONCLUSION: Diabetic duration was independently associated with increased risk of having diabetes-related complications without threshold. Monitoring of complications in patients having long-standing diabetes is warranted in order to provide appropriate management.en_US
dc.description.affiliationDepartment of Medicine, Faculty of Medicine, Prince of Songkla University, Sonkhla 90110, Thailand. Irattana@medicine.psu.ac.then_US
dc.identifier.citationLeelawattana R, Pratipanawatr T, Bunnag P, Kosachunhanun N, Suwanwalaikorn S, Krittiyawong S, Chetthakul T, Plengvidhya N, Benjasuratwong Y, Deerochanawong C, Mongkolsomlit S, Ngarmukos C, Rawdaree P. Thailand diabetes registry project: prevalence of vascular complications in long-standing type 2 diabetes. Journal of the Medical Association of Thailand. 2006 Aug; 89 Suppl 1(): S54-9en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/43848
dc.language.isoengen_US
dc.source.urihttps://www.mat.or.th/journal/all.phpen_US
dc.subject.meshAgeden_US
dc.subject.meshCardiovascular Diseases --epidemiologyen_US
dc.subject.meshCross-Sectional Studiesen_US
dc.subject.meshDiabetes Complicationsen_US
dc.subject.meshDiabetes Mellitus, Type 2 --physiopathologyen_US
dc.subject.meshDisease Progressionen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle Ageden_US
dc.subject.meshPrevalenceen_US
dc.subject.meshProgram Developmenten_US
dc.subject.meshProgram Evaluationen_US
dc.subject.meshRegistriesen_US
dc.subject.meshRisk Factorsen_US
dc.subject.meshThailand --epidemiologyen_US
dc.subject.meshTime Factorsen_US
dc.titleThailand diabetes registry project: prevalence of vascular complications in long-standing type 2 diabetes.en_US
dc.typeJournal Articleen_US
dc.typeMulticenter Studyen_US
dc.typeResearch Support, Non-U.S. Gov'ten_US
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