Complement components (C3, C4) as Inflammatory markers in asthma.

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dc.contributor.authorFattah, Mohammed Abdel
dc.contributor.authorBaz, Mohammed El
dc.contributor.authorSherif, Ashraf
dc.contributor.authorAdel, Alia
dc.date.accessioned2012-10-31T04:11:32Z
dc.date.available2012-10-31T04:11:32Z
dc.date.issued2010-07
dc.description.abstractObjective. To assess the serum levels of complement factors C3 and C4 in Egyptian asthmatic children. Methods. This case-controlled study comprised of 60 Egyptian children with the diagnosis of bronchial asthma (not in acute attack) and 60 age-and sex-matched healthy controls. All candidates were subjected to a thorough clinical study, complete blood counts, absolute eosinophil count and serum complements (C3, C4). Results. Serum C3 was significantly higher in asthmatics when compared to controls (140.60 ± 38.80 mg/dl vs 107.70 ± 45.00 mg/dl respectively, (p = 0.01). However, differences in serum C4 levels were not significant (41.30±48.80 mg/dl vs 44.60 ± 39.70 mg/dl respectively, p = 0.69). There was a significant positive correlation between severity of asthma and serum C3 (p=0.02) but not with serum C4. Conclusions. Serum levels of C3 - but not C4 - are elevated in children with stable asthma, with a positive correlation between serum C3 and severity of asthma.en_US
dc.identifier.citationFattah Mohammed Abdel, Baz Mohammed El, Sherif Ashraf, Adel Alia. Complement components (C3, C4) as Inflammatory markers in asthma. Indian Journal of Pediatrics. 2010 July; 77(7): 771-773.en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/142627
dc.language.isoenen_US
dc.source.urihttps://medind.nic.in/icb/t10/i7/icbt10i7p771.pdfen_US
dc.subjectAsthmaen_US
dc.subjectChildrenen_US
dc.subjectComplementen_US
dc.subject.meshAsthma --blood
dc.subject.meshAsthma --diagnosis
dc.subject.meshBiological Markers --blood
dc.subject.meshCase-Control Studies
dc.subject.meshChild, Preschool
dc.subject.meshComplement C3 --metabolism
dc.subject.meshComplement C4 --metabolism
dc.subject.meshEgypt
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMatched-Pair Analysis
dc.subject.meshSeverity of Illness Index
dc.titleComplement components (C3, C4) as Inflammatory markers in asthma.en_US
dc.typeArticleen_US
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