Effect of prehabilitation on outcomes following upper gastrointestinal surgery: a systematic review and meta-analysis

Simple item page
dc.contributor.authorFindlay, Nen_US
dc.contributor.authorHan, Sen_US
dc.contributor.authorPillinger, N.en_US
dc.date.accessioned2025-05-12T09:33:04Z
dc.date.available2025-05-12T09:33:04Z
dc.date.issued2024-12
dc.description.abstractIt is accepted in several areas of surgery that prehabilitation can improve post-operative outcomes. Prehabilitation describes preoperative interventions aimed at optimizing patient condition prior to surgery to improve postoperative outcomes. It is hypothesized that prehabilitation reduces postoperative complications in the setting of upper gastrointestinal surgery. A systematic search strategy was performed based on a research question formulated with reference to the PICO framework. Eligible studies were those that included a predefined prehabilitation intervention, a comparison to usual care and conducted on patients undergoing upper gastrointestinal surgery. Included studies were evaluated for bias and underwent data extraction. Meta-analysis was also performed for outcomes where possible. Eight studies met criteria for inclusion in this review. The nature and length of prehabilitation programs varied widely, with interventions lasting from two to six weeks. Reported outcomes included post-operative pulmonary complications, mortality and length of hospital stay. A meta-analysis was undertaken for mortality and postoperative pulmonary complications. Meta-analysis showed postoperative pulmonary complications were reduced (RR0.68, 95% CI 0.50-0.93) in the intervention group compared to the control group, as was mortality (RR 0.59, 95% CI 0.35-1.00). Prehabilitation, especially inspiratory muscle training appears to be effective in reducing pulmonary complications in patients scheduled for upper gastrointestinal surgery. With the available data it is uncertain if this translates to reduced length of stay or mortality. There is scope for further research to better define a role for prehabilitation in upper gastrointestinal surgery, specifically the optimal prehabilitation modality and length.en_US
dc.identifier.affiliationsDepartment of Surgery, Wagga Wagga Base Hospital, Wagga Wagga, NSW, Australiaen_US
dc.identifier.affiliationsNepean Hospital, Penrith, NSW Australiaen_US
dc.identifier.affiliationsDepartment of Anaesthetics, Royal Prince Alfred Hospital, Camperdown, NSW, Australiaen_US
dc.identifier.citationFindlay N, Han S, Pillinger N.. Effect of prehabilitation on outcomes following upper gastrointestinal surgery: a systematic review and meta-analysis . International Surgery Journal. 2024 Dec; 11(12): 2055-2062en_US
dc.identifier.issn2349-3305
dc.identifier.issn2349-2902
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/247270
dc.languageenen_US
dc.publisherMedip Academyen_US
dc.relation.issuenumber12en_US
dc.relation.volume11en_US
dc.source.urihttps://doi.org/10.18203/2349-2902.isj20243546en_US
dc.subjectPrehabilitationen_US
dc.subjectUpper GI surgeryen_US
dc.subjectInspiratory muscle trainingen_US
dc.subjectPulmonary complicationsen_US
dc.titleEffect of prehabilitation on outcomes following upper gastrointestinal surgery: a systematic review and meta-analysisen_US
dc.typeJournal Articleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
isj2024v11n12p2055.pdf
Size:
507.12 KB
Format:
Adobe Portable Document Format
Download
Collections
International Surgery Journal