Hodgkins Lymphoma in a Child with Sickle Cell Anaemia: A Case Report

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dc.contributor.authorK. Sree, Laxmien_US
dc.contributor.authorTriveni, Bhopalen_US
dc.contributor.authorSai Mallik, Arjunen_US
dc.contributor.authorV.S. Aparna, Akellaen_US
dc.date.accessioned2019-12-02T09:49:13Z
dc.date.available2019-12-02T09:49:13Z
dc.date.issued2018-11
dc.description.abstractTo study the co existence of Hodgkins lymphoma in sickle cell disease in a 10-year-old boy who is also a known case of sickle cell anaemia presented to out centre with symptoms of fever, weight loss. History of previous blood transfusions was given. On clinical examination, he was found to have pallor, generalised lymphadenopathy, splenomegaly. Complete blood picture revealed haemoglobin of 9 g/dl, white blood cell count of 12,000/cu mm, platelet count of 2 lakhs. Biopsy from the cervical lymph node revealed effacement of lymph nodal architecture with replacement by scattered atypical mononuclear and binucleate Reed–Sternberg cells with moderate cytoplasm, large vesicular nucleus and prominent eosinophilic nucleoli against a background of, mixed population of small lymphocytes, plasma cells and few eosinophils. Immuno histochemistry revealed positive expression of CD15, CD30, Pax-5 in the atypical cells and thus proved to be Hodgkins lymphoma.en_US
dc.identifier.affiliationsAssistant Professor, M.N.J Institute of Oncology & Regional Cancer Centre, Osmania Medical College and General Hospital, Hyderabad, Telangana, Indiaen_US
dc.identifier.affiliationsProfessor, M.N.J Institute of Oncology & Regional Cancer Centre, Osmania Medical College and General Hospital, Hyderabad, Telangana, Indiaen_US
dc.identifier.affiliationsSenior Lecturer, Department of General pathology, M.N.J Institute of Oncology & Regional Cancer Centre, Osmania Medical College and General Hospital, Hyderabad, Telangana, Indiaen_US
dc.identifier.citationK. Sree Laxmi, Triveni Bhopal, Sai Mallik Arjun, V.S. Aparna Akella. Hodgkins Lymphoma in a Child with Sickle Cell Anaemia: A Case Report. Indian Journal of Mednodent and Allied Sciences. 2018 Nov; 6(3): 100-103en_US
dc.identifier.issn2347-6192
dc.identifier.issn2347-6206
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/186104
dc.languageenen_US
dc.publisherAssociation of Medical Dental and Allied Sciencesen_US
dc.relation.issuenumber3en_US
dc.relation.volume6en_US
dc.source.urihttps://dx.doi.org/10.5958/2347-6206.2018.00013.4en_US
dc.subjectSickle cell diseaseen_US
dc.subjectHodgkins lymphomaen_US
dc.subjectHodgkins lymphoma in sickle cell diseaseen_US
dc.subjectNodular sclerosisen_US
dc.subjectEpstein–Barr virusen_US
dc.subjectReed–Sternberg (HRS) cellsen_US
dc.titleHodgkins Lymphoma in a Child with Sickle Cell Anaemia: A Case Reporten_US
dc.typeJournal Articleen_US
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