Bacterial profile from suspected maternal sepsis and colonization cases: A step towards prevention of neonatal sepsis

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dc.contributor.authorSurbhien_US
dc.contributor.authorJain, Manishaen_US
dc.contributor.authorMishra, Neelangien_US
dc.contributor.authorGaind, Rajnien_US
dc.date.accessioned2020-09-24T07:21:10Z
dc.date.available2020-09-24T07:21:10Z
dc.date.issued2019-10
dc.description.abstractBackground: Transmission of pathogens can occur through direct materno-fetal contact during antepartum period or delivery.Presence of maternal reproductive tract colonization or bacterial infections during pregnancy increases the risk of puerperal sepsisand early onset neonatal sepsis (EONS). This study was thus planned to screen the etiological agents and antibiogramfromsuspected maternal sepsis/ colonization cases.Materials and methods:Data was collected over a period of 1 year (September2017- September 2018). Clinical samples-placental membrane, placental tissue, retained product of conception (RPOCs) and highvaginal swabs (HVS) received for screening of maternal sepsis or colonization were processed as per conventionalmicrobiological techniques. Antimicrobial sensitivity was performed as per CLSI guidelines.Result:A total of 2405 maternalsamples were included in the study. Only about 13.18% ( 317 samples) showed the presence of bacterial isolate, Escherichia coli(39%) was the predominant etiological agent isolated followed by Staphylococcus aureus(18%)and Enterococcus species (17%).There was an alarming level of drug resistance seen in both the gram positive and negative organisms.Conclusion:Introduction ofpathogens into the female genital tract is a major risk factor for development of uterine infections and chorioamnionitis which caneventually lead to puerperal sepsis and Early onset neonatal sepsis. EONS. As seen in the present study the organisms such asEscherichia coli and Staphylococcus aureusisolated from maternal sepsis and colonization cases are the same organismsimplicated from EONS.In view of increase in drug-resistant organisms prompt detection and treatment of maternal infectionsbecomes crucial to prevent neonatal infections.en_US
dc.identifier.affiliationsSenior Senior Resident, VardhmanMahavir Medical college and Safdarjung Hospital, Delhien_US
dc.identifier.affiliationsAssociate Professor, VardhmanMahavir Medical college and Safdarjung Hospital, Delhien_US
dc.identifier.affiliationsConsultant and Professor, Department of Microbiology, VardhmanMahavir Medical college and Safdarjung Hospital, Delhien_US
dc.identifier.citationSurbhi, Jain Manisha, Mishra Neelangi, Gaind Rajni. Bacterial profile from suspected maternal sepsis and colonization cases: A step towards prevention of neonatal sepsis. International Journal of Medical and Health Sciences . 2019 Oct; 8(4): 72-76en_US
dc.identifier.issn2277-4492
dc.identifier.placeIndiaen_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/203106
dc.languageenen_US
dc.publisherInternational Journal of Medical and Health Sciencesen_US
dc.relation.issuenumber4en_US
dc.relation.volume8en_US
dc.source.urihttps://www.ijmhs.net/articles/5de7c6bedb409.pdfen_US
dc.subjectMaternal Colonizationen_US
dc.subjectNeonatal sepsisen_US
dc.subjectMulti drug resistanten_US
dc.titleBacterial profile from suspected maternal sepsis and colonization cases: A step towards prevention of neonatal sepsisen_US
dc.typeJournal Articleen_US
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