Spectrum of malignancy in mixed tumors of salivary gland: a morphological and immunohistochemical review of 23 cases.

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dc.contributor.authorQureshi, Asimen_US
dc.contributor.authorBarakzai, Abraren_US
dc.contributor.authorSahar, Najam Ulen_US
dc.contributor.authorGulzar, Rubinaen_US
dc.contributor.authorAhmad, Zubairen_US
dc.contributor.authorHassan, Sheema Hen_US
dc.date.accessioned2009-04-01en_US
dc.date.accessioned2009-05-29T11:01:58Z
dc.date.available2009-04-01en_US
dc.date.available2009-05-29T11:01:58Z
dc.date.issued2009-04-01en_US
dc.description.abstractMalignancy arising in mixed tumors of the salivary gland is a distinct entity that can occur sporadically or in association with a background of pleomorphic adenoma. Carcinoma arising with a background of pleomorphic adenoma is well documented. However, there are rare occurrences of aggressive de novo carcinosarcomas of the parotid that have been reported. Various cell lineages such as the epithelial glandular cells and the stromal spindle cells are involved. We report 23 cases of tumors of the salivary gland comprising 18 cases of carcinoma ex pleomorphic adenoma, four cases of carcinosarcoma of the parotid and one case of benign metastasizing pleomorphic adenoma. The occurrence of various malignancies suggests that this phenomenon is not very uncommon and should be looked for when reporting a mixed tumor.en_US
dc.description.affiliationSection of Histopathology, Aga Khan University, Karachi, Pakistan. asim.qureshi@aku.eduen_US
dc.identifier.citationQureshi A, Barakzai A, Sahar NU, Gulzar R, Ahmad Z, Hassan SH. Spectrum of malignancy in mixed tumors of salivary gland: a morphological and immunohistochemical review of 23 cases. Indian Journal of Pathology & Microbiology. 2009 Apr-Jun; 52(2): 150-4en_US
dc.identifier.urihttps://imsear.searo.who.int/handle/123456789/73076
dc.language.isoengen_US
dc.source.urihttps://www.ijpmonline.orgen_US
dc.titleSpectrum of malignancy in mixed tumors of salivary gland: a morphological and immunohistochemical review of 23 cases.en_US
dc.typeJournal Articleen_US
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