International Journal of Medical Science and Public Health

Permanent URI for this collection

https://imsear.searo.who.int/handle/123456789/149614

Editor: Dr. Jay Charan

ISSN: 2320–4664 (Print)

Frequency: 3 issues a year

Language: English

Open Access Peer-reviewed journal

Web site: https://www.ijmsph.com/

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Browsing International Journal of Medical Science and Public Health by Subject "Abnormal Uterine Bleeding"

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    Histopathological interpretation of endometrium in abnormal uterine bleeding.
    (2014-07) Shah, Rupal; Dayal, Anupama; Kothari, Sadhana; Patel, Shanti; Dalal, Bharati
    Background: Abnormal uterine bleeding is one of the most frequent problems in life of an adult female. Accurate analysis of endometrium & localization of intrauterine lesion is the goal to effective management & better outcome of problem. Aims & Objective: To evaluate various histopathological features in D & C and/or hysterectomy in patients presenting with abnormal uterine bleeding and to find the efficacy of D & C as a better, cost effective and minimally invasive tool for screening in patients with AUB. Materials and Methods: The present study was conducted in Department of Pathology, tertiary care hospital, Ahmedabad, Gujarat, India over a period of one and half years. A total 320 patients aged 20 years & above, presenting with AUB were included. Endometrial samples were analysed, histopathological changes identified and classified. Results: Age of patients ranged from 21 to 70 years mean age being 42.6 ± 6.9 years, maximum patients (53.4%) belonged to 41-50 years of age group. Most common histopathological pattern was normal cyclical endometrium (47.3%) followed by endometrial hyperplasia (42.9%). Endometrial hyperplasia was most common (57.1%) in perimenopausal age group (41-50 years). The diagnostic accuracy of D &C was found to be 93.4%; amongst all histopathological patterns it was maximum for complex hyperplasia (typical and atypical) and simple atypical hyperplasia. Conclusion: Endometrial causes of AUB are age related therefore it is specially recommended in women of perimenopausal age group to rule out preneoplastic and neoplastic etiology. D & C is an accurate, minimally invasive outdoor procedure for detecting endometrial pathology especially hyperplasia.