Browsing by Author "Yadav, B. K."

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    Derangement of liver function tests in dengue patients
    (Medip Academy, 2024-01) Chaudhary, R. D.; Jha, S. D.; Sah, V. K.; Mandal, R. N.; Pandey, M.; Yadav, B. K.; Mahato, T.; Sah, K. K.; Sah, A.; Chaudhary, R. P.
    Background: Changes in the liver function test may serve as an early marker for timely diagnosis and identification of patients who may develop severe dengue. The purpose of this study was to examine the link between dengue fever severity and liver function test. Methods: This prospective observational study was conducted in the Department of General Medicine, Madhesh Institute of health sciences, provincial hospital, Janakpurdham in which we included dengue positive patients (aged 18 years or more) based on NS1 antigen or high titer on IgM/IgG testing from July 2023 till August 2023. We excluded patients with diseases like malaria, cirrhosis of liver, enteric fever, viral hepatitis or any other disease or taking any medication which can derange LFT. Results: We included 96 patients fulfilling the study criteria. Of these, 71% had DF, 22% had DHF and 7% had DSS. Among liver enzymes, mean AST of the patients was significantly higher in DSS group of patients (775.19�.65 U/l), as compared to those in the DF and DHF group of patients, p value <0.01. Similarly, mean ALT of the patients was significantly higher in DSS group of patients (387.8�.6 U/l), as compared to those in the DF and DHF group of patients, p value<0.01. On the contrary, mean alkaline phosphatase levels were similar between the three patient groups. Conclusions: Based on the results our study, we conclude that raised AST and ALT levels were significantly associated with severity of DSS and DHF. Patients with dengue infection should have a baseline liver function test and subsequent LFT monitoring to detect early hepatic impairment.
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    Evaluation of Paramedical Student’s Knowledge on COVID-19: A Comparative Study
    (Janaki Medical College, 2023-04) Yadav, K.; Prakash, S.; Yadav, B. K.; Pokhrel, B.
    Background & Objectives: The COVID-19 pandemic has presented the world community with its greatest challenges so far. Paramedics play a crucial role in providing pre-hospital care to patients who require urgent medical attention in clinical settings. Therefore, the aim of the study was to evaluate the knowledge on COVID-19 among health assistant (HA) students studying in different paramedical colleges in Janakpurdham. Material and Methods: A descriptive cross-sectional study was performed utilizing a structured questionnaire to acquire responses from HA Students studying in different colleges of Janakpurdham in the months of April and May 2022. Descriptive analysis was applied to calculate the frequencies and proportions. A p-value less than 0.05 were considered as significant. Results: Out of total 360 students, 280 were enrolled. The majority of students were under 20 years old. All of the students were aware of the COVID-19 infection at National Human Resource Development Academy (NHRDA) and Mithila Technical Academy (MTA) colleges, with the exception of 3.61% Care Medical Center (CMC) students. A large percentage of students (52.80% boys , 47.19% girls) responded that the respiratory tract is the primary route by which COVID-19 infections are spread, followed by the students from NHRDA and CMC. Most of the students from all colleges received satisfactory scores on the COVID-19 knowledge test. There was negative association of score of knowledge between 1st, 2nd and 3rd year students of CMC and MTA (p=0.96 and p=0.11) respectively. However, there was positive association of score of knowledge between 1st, 2nd and 3rd year NHRDA students (p=0.01). Conclusion: The majority of college students studying at different colleges had satisfactory knowledge, while a moderate number of students had poor and just a few had good knowledge scores on the COVID-19. In order to increase knowledge, various kinds of strategies, regulations, and initiatives should be accomplished and implemented effectively throughout the lower to higher level education.
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    Nondestructive Analysis of Litchi Fruit Quality Using FT-NIR Spectroscopy
    (Science Domain International, 2018-06) Reddy, N. Sreedhar; Yadav, B. K.
    A non-destructive optical method based on near-infrared spectroscopy has been used for the evaluation of litchi fruit quality. Diffuse reflectance measurements (12500–3600 cm-1), physical, and biochemical measurements were performed individually on 100 litchi fruits of cv.Shahi cultivar harvested at different ripening stages. Relationships between spectral wavelengths and quality attributes were evaluated by application of chemometric techniques based on partial least squares (PLS) regression. The fruit set was divided into two groups: 60 fruits for calibration and 39 for validation. Good prediction performance was obtained for pH, soluble solids, and titratable acidity with correlation coefficients of 0.96, 0.91 and 0.94 respectively and root mean square errors of prediction of 0.009, 0.291ºBrix and 0.011% malic acid respectively. For the other quality traits such as vitamin C and color the prediction models were not satisfactorily accurate due to the higherror of calibration and prediction.