Browsing by Author "Verma, R K"
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Item Aluminium Phosphide Poisoning: Late Presentation as Oesophageal Stricture(2006-10) Verma, R K; Gupta, S N; Bahl, D V; Gupta, AmitItem Application of enzyme amplified mycobacterial DNA detection in the diagnosis of pulmonary & extra-pulmonary tuberculosis.(2003-12-12) Tiwari, Vandana; Jain, Amita; Verma, R KBACKGROUND & OBJECTIVES: As isolation of Mycobacterium tuberculosis in culture requires a long time, there is a need for simple rapid method for direct detection of M. tuberculosis from clinical specimens. Amplified nucleic acid hybridization assays such as polymerase chain reaction (PCR) have shown promising results. In the present study, the sensitivity of PCR assay was assessed over smear microscopy for rapid diagnosis of tuberculosis in pulmonary and extra-pulmonary samples from patients suspected to have tuberculosis. METHODS: A total of 37 clinical samples from patients with pulmonary tuberculosis and 133 from patients with extra-pulmonary tuberculosis were subjected to Ziehl-Neelsen staining for smear preparation and PCR for detection of mycobacterial DNA. RESULTS: It was observed that 100 per cent of acid fast bacilli (AFB) positive and 35.7 per cent of AFB negative pulmonary samples and 82.76 per cent of AFB positive and 56.73 per cent of AFB negative extra-pulmonary samples were positive for mycobacterial DNA detection. Total positivity rates of DNA amplification method in pulmonary and extra-pulmonary samples were 75.67 per cent and 61.7 per cent respectively which were significantly higher in comparison with AFB positivity, which was 62.16 per cent in pulmonary and 21.8 per cent in extra-pulmonary samples (P < 0.05 and P < 0.001 respectively). INTERPRETATION & CONCLUSION: Routine application of DNA amplification method in diagnosis of AFB negative patients with pulmonary or extra-pulmonary tuberculosis may be a useful tool for detection of M. tuberculosis.Item Bio-social determinants of birth weight.(1977-02-01) Ghosh, S; Hooja, V; Mitta, S K; Verma, R KItem Comparative value of glutamic oxaloacetic transaminase and lactic dehydrogenase enzyme pattern in serum and cerebrospinal fluid in acute cerebrovascular accidents.(1989-10-01) Shukla, R P; Chadda, S; Chadda, V S; Gupta, R P; Verma, R KA study of glutamic oxaloacetic transaminase (GOT) and lactic dehydrogenase (LDH) enzymes in serum and cerebrospinal fluid (CSF) was carried out on 30 cases of acute cerebrovascular accident (CVA) to determine their role in precise diagnosis and prognosis of the cases. The CSF GOT and LDH activities were well correlated with the severity, mortality and peak and proper timing in relation to infarct, same is about serum GOT. A characteristic rise of GOT and LDH was observed in cerebral haemorrhage especially in fatal cases. However, in cerebral thrombosis and embolism specially in non-fatal cases, the enzyme change was not so marked. GOT and LDH enzyme pattern in CSF and serum may, therefore, serve as an early, relatively easy and widely available tool for differential diagnosis and prognosis of cases of acute CVA.Item Correlation Between Tsh And Body Mass Index In Male And Female Patients With Subclinical Hypothyroidism(Era's Lucknow Medical College and Hospital, 2019-01) Garg, Om prakash; Abdussalam; Singh, Seema; Verma, R KHypothyroidism is a syndrome resulting from thyroid hormone deficiency or rarely inefficacy. It is a common endocrinological problem affecting especially women and the elderly. Thyroid hormones play an important role in synthesis, metabolism and mobilization of lipids. One of the most important symptoms of hypothyroidism is weight gain or inability to lose weight. The rapid increase in the prevalence of obesity in the past 20 to 30 years emphasizes the important role of lifestyle and environmental factors, because genetic changes could not have occurred so rapidly. Obesity is a complicated process that depends on signals of satiety and hunger, genetics, endocrine abnormalities, and other factors. Our study purposes to investigate the relationship between BMI and thyroid function in patients of subclinical hypothyroidism. Objective of this study is to correlate thyroid stimulating hormones (TSH) and body mass index (BMI) in male and female patients with subclinical hypothyroidism. This cross sectional study included 42 Subclinical hypothyroid patients, both males and females between 20-45 years of age and without a history of alcohol or tobacco consumption, history of any cardiovascular disorders or diabetes mellitus and any drug history like corticosteroids, beta blockers. and TSH test estimated by VITROS 5600 integrated analyzer and correlated with body mass index. The results showed a positive Correlation analysis in subclinical Hypothyroid males between BMI and TSH, (r= 0.47), which was found to be statistically significant (p=0.02*) in case of subclinical Hypothyroid females the results indicated positive correlation between BMI and TSH (r= 0.58) which was found to be statistically significant (p=0.005*). A strong positive correlation between Body Mass Index (BMI) and Thyroid stimulating hormones (TSH).Item Immunisation status in an urban community.(1976-10-01) Hooja, V; Ghosh, S; Mittal, S K; Verma, R KItem Meige's syndrome.(1993-03-01) Verma, R K; Gupta, B K; Kochar, S K; Poonia, A; Kochar, D KA case of Meige's syndrome is reported who presented with blepharospasm and oromandibular dystonia along with dislocation of jaw, due to severe dystonia. Such severe form of dystonia are very rare.Item Perianal tuberculous ulcer in an immuno-competent patient.(2009-10) Rawat, Jagdish; Verma, R K; Sindhwani, Girish; Dua, Ruchi; Negi, GeetaPerianal tuberculosis, without the presence of any previous or active pulmonary infection, is extremely rare. A wide range of differential diagnosis for perianal ulcers might be one reason for a possible delay in establishing this diagnosis.Item Psychosocial antecedents of myocardial infarction.(1983-05-01) Gupta, L N; Verma, R KItem Socio-cultural factors affecting breast feeding and other infant feeding practices in an urban community.(1976-11-01) Ghosh, S; Gidwani, S; Mittal, S K; Verma, R KItem Wolff-Parkinson-White syndrome with paroxysmal atrial fibrillation in pseudohypertrophic muscular dystrophy (Duchenne type).(1973-10-01) Agarwal, R K; Misra, D N; Verma, R K