Browsing by Author "Ubale, Milind"

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    A Hospital Based Study On Neonatal Outcome In Monochorionic And Dichorionic Twin Pregnancies
    (World Wide Journals, 2019-05) Ramteke, Mamta; Sable, Pavan; Gaikwad, Sunita; Ubale, Milind
    Background: Twin pregnancies account for 2 to 4% of the total number of births. Twin pregnancies are associated with signicantly higher morbidity and mortality than are singleton pregnancies. Among the twin pregnancies, Dichorionic pregnancies occur in 70% of the total twin pregnancies. Monochorionic twins are at higher risk twins for perinatal complications. The objective of the present study is to analyze neonatal outcomes associated with Monochorionic and Dichorionic twin pregnancies. Material and Methods: The study was Retrospective and Hospital based study conducted in Tertiary Care Hospital in Mumbai in 2018. The sample size was 50 (N=50). The patients with maternal co-morbidities like DM or other systemic illness were excluded from the study. The patients were divided into two groups, viz. Monochorionic or Dichorionic twins. The maternal age and its association with Monochorionic and Dichorionic twin pregnancy are studied. The neonatal outcome in Monochorionic and Dichorionic twins were then analyzed in terms of Birth weight, NICU stay, Neonatal deaths, etc. Statistical analysis: The maternal age and the various neonatal outcomes in Monochorionic and Dichorionic twin pregnancy were recorded. The student t test was used to compare the difference in both groups. Results: The maternal age was almost similar in both Monochorionic and Dichorionic twin pregnancies. The mean Birth Weight was more in Dichorionic group (p < 0.05). The Neonatal Outcomes like IUFD, TTTS and Discordant growth were more common in Monochorionic group as compared to Dichorionic group. Conclusion and Recommendations: Twin pregnancy rates have increased in the past 25-30 years, particularly in developing countries. The reasons may be more advanced maternal age and increased use of assisted reproductive techniques. The neonatal mortality and morbidity in twin deliveries is high in Monochorionic pregnancy as compared to Dichorionic pregnancy. The early identication of chorionicity in early pregnancy is necessary to prevent neonatal complications.
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    Paecilomyces keratitis: a case report
    (Wolters Kluwer – Medknow, 2024-12) Choudhury, Debapriya Das; Ubale, Milind; Baranwal, Rimjhim; Nanoty, Vaibhavi; Patel, Mayuri
    Ocular trauma involving vegetative matter is the most common cause of keratitis in ophthalmic practice in India, with many cases resulting in fungal keratitis or corneal ulceration. Here, we present a case of fungal keratitis due to Paecilomyces lilacinus that was successfully managed with oral and topical antifungal therapy, avoiding surgical intervention. The patient, a female, presented with a corneal abscess, conjunctival congestion, and persistent pain in her right eye after sustaining an ocular injury from vegetative matter. Based on the clinical signs, a provisional diagnosis of fungal keratitis was made, and treatment with 5% natamycin eye drops was initiated. Potassium hydroxide mount findings indicated fungal hyphae, leading to the addition of oral voriconazole due to suspected deuteromycosis. Fungal culture confirmed the presence of P. lilacinus. Gradually, the patient improved with antifungal therapy over a month without surgical intervention.