Browsing by Author "Sunday, Ezekwe Ahamefula"
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Item Serum Electrolytes and Red Blood Cell Membrane Potential of Hypertensive Patients(International Blood Research & Reviews, 2019) Constance, Nwadike; Ijeoma, Nosiri Chidi; Adindu, Eze; Chimaraoke, Onyeabo; Sunday, Ezekwe Ahamefula; Catherine, OnyejiekweSerum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis were investigated. A total of 50 volunteer subjects were used for the study. Thirty (30) of the volunteer subjects were hypertensive subjects and were used as test subjects; while the remaining 20 subjects were healthy subjects with normal blood pressure used as normentensive subjects (control). Results observed showed increased red blood cell (RBC) K+ and Cl- in hypertension subjects against normentensive subjects. Apart from K+ which reduced significantly (p<0.05), other electrolyte ions of the serum increased significantly (p<0.05) in hypertensive subjects against normentensive subjects. However, Na+ and Cl- membrane potential was not significantly (p>0.05) altered in hypertensive subjects against normotensive subjects while K+ was significantly (p<0.05) altered. The observed alterations in the parameters investigated in hypertensive subjects in the present study could be as a result of a host of derangements involving electrolyte metabolism, altered membrane transport and a possible increase in membrane fragility. This study has shown the serum electrolyte and red blood cell membrane potential of hypertensive patients in Owerri metropolis.