Browsing by Author "Songtrus, J"
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Item High prevalence of bancroftian filariasis in Myanmar-migrant workers: a study in Mae Sot district, Tak province, Thailand.(1999-07-08) Triteeraprapab, S; Songtrus, JAlthough the prevalence of lymphatic filariasis in the Thai population is low, migration of Myanmar labor into Thailand may increase the incidence of bancroftian filariasis. Epidemiology of filariasis in Myanmars has not been precisely determined. By using microscopic examination, we found that the microfilarial rate in 654 Myanmar migrants working in Mae Sot, Tak province, was 4.4 per cent. The highest microfilarial rate was found in males aged 21-30 years (6.8%). History of mosquito bites was significantly correlated with microfilaremia. The majority of Myanmar migrants (55.5%) have been staying in Thailand 1-6 years; most (82.0%) have never been back to Myanmar. Seventy-nine per cent of infected Myanmars were from Moulmein (Maulamyine) city. Since these migrants carry the parasite with high infected rate and the mosquito vector Culex quinquefasciatus is also prevalent in Thailand, Thai people are at high risk of acquiring this disease if good control and prevention strategies are not implemented.Item ICT filariasis test: a new screening test for Bancroftian filariasis.(1999-03-01) Phantana, S; Sensathein, S; Songtrus, J; Klagrathoke, S; Phongnin, KBancroftian filariasis can be detected by using the ICT Filariasis test kit which is composed of specific polyclonal and monoclonal antibodies to Wuchereria bancrofti antigen. Chromatographic reaction with serum or plasma shows a result within 5 minutes. When compared with 454 thick blood films (standard smear method) within the same study, the ICT Filariasis test had sensitivity = 100%, specificity = 96.37%, efficiency = 96.70%, predictive value positive (PVP) = 70.70%, predictive value negative (PVN) = 100%. Compared with 454 membrane filtration technic (MFT), the MFT had sensitivity = 95.10%, specificity = 99.50%, efficiency = 99.12%, PVP = 95.10%, PVN = 99.50%. When we compared capillary tube technic (CAP) with TBF, CAP showed sensitivity = 85.40%, specificity = 100%, efficiency = 98.68%, PVP = 100%, PVN = 98.60%. With the convenience, high sensitivity-efficiency, lack of cross-reactions, no night blood collection, single reagent and rapidity of the test, the ICT Filariasis test can be recommended for screening of Bancroftian filariasis, and is suitable for the confirmation of suspected cases in the field where microscopic diagnosis is not available.