Browsing by Author "Singh, V. K."
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Item Cervical cancer: perception of peripheral health workers in Lucknow: a cross-sectional study(Medip Academy, 2019-04) Ansari, Arshi; Agarwal, Monika; Singh, V. K.; Kumari, Nutan; Deo, SujataBackground: Cervical cancer is one of the most prevalent cancers among Indian women. Cervical cancer incidence reduces dramatically when effective screening programs linked with access to treatment are in place and are readily accessible. Peripheral health workers (PHWs) being frontline workers have a major influence on raising awareness among community about acceptability of available screening programmes. This study was thus conducted to assess the awareness of PHWs regarding risk factors, signs and symptoms, early detection and prevention for cervical cancer.Methods: A questionnaire-based study was conducted among 450 PHWs (ASHAs and BHWs). Information was collected regarding their bio-social characteristics, awareness about female cancers, risk factors, signs/symptoms, early detection methods and services available for screening and prevention of cervical cancer.Results: Awareness of different aspects of cervical cancer was found to be very low. Only eight per cent of the PHWs had good awareness score. BHWs obtained statistically significant better mean scores as compared to ASHAs. Few (7.6%) PHWs had received training for any type of female cancers. Only 17 per cent of the PHWs were aware of HPV vaccine availability and only 29 per cent from them could name the vaccine.Conclusions: Majority of the PHWs had poor awareness about cervical cancer and available screening facility in our health system. They had almost no idea of availability of free HPV vaccination at the Sampoorna clinics. This low level of awareness calls for regular training of PHWs on cervical cancer which would ultimately trickle down to the community.Item Comparison of metabolic effects of glimepride and sitagliptin with metformin in patients suffering from type 2 diabetes mellitus in a tertiary care hospital(Medip Academy, 2019-07) Singh, Preeti; Choudhary, Ruchi; Singh, V. K.; Matreja, Prithpal S.Background: Diabetes mellitus (DM) is one of the major causes of mortality & morbidity, and patient’s with better control of glycaemic parameters have lesser chronic complications associated with it. Though monotherapy with metformin is first choice for T2DM but is effective in less than 50% of patient and they should be managed with two drug therapy. Both Glimepiride and Sitagliptin are effective with metformin but there has been no study done in this region hence, we planned to study comparison of effects of glimepiride and sitagliptin with metformin in patient of T2DM.Methods: This prospective, open-label, randomized study was done in all patient diagnosed with T2DM, not adequately managed by metformin alone. The patient was divided into two group G (Glimepiride with Metformin) and Group S (Sitagliptin with Metformin) and had a follow up at 3 and 6 months. The biochemical parameters were assessed at 12 weeks and 24 weeks.Results: The result of this study show that both glimepiride and sitagliptin with metformin significantly (p<0.05) lowered both the fasting blood sugar as well as postprandial blood glucose at 3 and 6 months. Glimepiride was more effective in lowering (p<0.05) the plasma glucose at 3 months but both the drugs had comparable result at 6 months. This study also showed that glycosylated haemoglobin was lowered in both groups at three and six months as compared to Day 0 (p<0.05), with glimepiride having better control of glycosylated haemoglobin at 3 months with both groups having comparable result at 6 months.Conclusions: To conclude, this study compared effects of sitagliptin and glimepiride on glycaemic parameters in patients of T2DM and found that both drugs had comparable results.