Browsing by Author "Singh, V S"
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Item Chlamydial and gonococcal serology in women with tubal infertility.(1998-06-16) Tyagi, P; Singh, V SSera from 81 infertile women with tubal pathology and 40 controls were tested for the presence of antibodies against Chlamydia trachomatis & Neisserria gonorrhoeae. Indirect immunoperoxidase test (Ipazyme kit) & Enzyme linked immuno sorbent assay (ELISA kit) were used for detection of chlamydial & gonococcal antibodies respectively. Antibodies to Ch. trachomatis were found in 74.07% of the infertile women and 5% in control group. Only a very low prevalence (4.93%) of antibodies to N. gonorrhoeae was found is infertile women as compared to nil in control group. Antibodies detection is a sensitive, specific and noninvasive test for diagnosing infertility.Item A comparative evaluation of plasma glycerol and free fatty acids in patients with ischaemic heart disease.(1979-01-01) Singh, V S; Sharma, A; Yeshowardhana,; Mehrotra, T N; Elhence, G PItem A comparative of the effect of tamoxifen on serum lipid and lipoprotein profile in premenopausal & postmenopausal women with breast carcinoma & associated risk of vascular complication.(2001-01-02) Sharma, D; Sharma, U; Bhatnagar, V B; Singh, V STo examine the effect of tamoxifen on serum lipid and lipoprotein profile of premenopausal and postmenopausal patients of breast carcinoma (with and without vascular disease) we performed a short term evaluation of serum lipid and lipoprotein profile of 38 pre and 42 post menopausal subjects of breast carcinoma (with and without vascular disease) at baseline and during 3 and 6 months of tamoxifen therapy. The lipid & Lp profile of premenopausal patients of Breast carcinoma without vascular disease showed no significant variation after 3 and 6 months of tamoxifen treatment than the corresponding baseline values, but in premenopausal subjects of breast cancer with vascular disease and post menopausal subjects of breast carcinoma (both with and without vascular disease), Serum TC, Apo-B and Lp (a) were significantly decreased and serum HDL and Apo A-I were elevated significantly, However serum TG remain unaltered in premenopausal patients of breast carcinoma with vascular disease but found to be elevated significantly in postmenopausal subjects of breast cancer, both, with and without vascular disease, after 3 and 6 months of tamoxifen treatment, than the corresponding baseline values. Also, the comparison of the results of the present study for pre and postmenopausal patients of breast cancer revealed that the administration of tamoxifen, as adjuvant therapy for breast cancer, is beneficial for postmenopausal patients of breast carcinoma with vascular disease as the drug minimises the risk of vascular disease by bringing significant improvement in serum lipid and Lp profiles of the patients but does not have any significant beneficial effect on familial hyperlipidemic patients of breast cancer.Item A comparative study of serum histaminase and serum glutamic oxaloacetic transaminase in acute myocardial infarction.(1979-07-01) Gupta, S K; Mehrotra, T N; Singh, V S; Elhence, G P; Mittal, H S; Mitra, AItem Comparison of sodium valproate and phenytoin as single drug treatment in generalised and partial epilepsy.(1991-08-01) Rastogi, P; Mehrotra, T N; Agarwala, R K; Singh, V SNinety four patients of generalised and partial epilepsy were randomly assigned to treatment with sodium valproate (49 cases) or phenytoin (45 cases). Serum levels were monitored. Cases were evaluated after 4, 12, 24 weeks of treatment. Both drugs were found to be equally effective in controlling generalised seizures. However, valproate is better in partial seizures. No correlation could be established. Side effects were minor with both the drugs.Item A comparison of the prevalence of hepatitis-B surface antigen (HBsAg) positivity among hospital and non-hospital personnel.(1985-09-01) Singhal, R K; Mital, H S; Mitra, A; Mehrotra, T N; Sharma, V; Singh, V S; Bindra, V KItem Creatine phospho kinase (C.P.K.) in diagnosis of cerebro vascular accidents.(1979-04-01) Charan, S; Mehrotra, T N; Singh, V S; Yesovardhan,; Sondhi, S P; Mital, H SItem Diabetes and rheumatoid factor.(1976-06-01) Mehrotra, T N; Singh, V SItem Effect of phenformin on serum cholesterol and triglyceride levels in diabetes mellitus.(1978-05-01) Singh, V S; Mehrotra, T N; Aggarwal, K; Sharma, A; Nath, KItem Effects of long-term therapy of propranolol and practolol on plasma-lipids after acute myocardial infarction.(1977-04-01) Singh, V S; Mehrotra, T N; Kirti, S; Aran, R K; Elhance, G PItem Fibrin degradation products in acute myocardial infarction.(1983-11-01) Arya, T V; Goel, V K; Mehrotra, T N; Singh, V S; Rajvanshi, S; Raka, M SItem Fibrinolytic activity in diabetics before and after chlorpropamide therapy.(1978-05-01) Mehrotra, T N; Mital, H S; Mishra, S D; Singh, V S; Kumar, MItem Hyperlipidaemia and pancreatitis associated with oral contraceptive therapy.(1975-02-01) Mehrotra, T N; Dwivedi, K K; Singh, M M; Mittal, H S; Singh, V SItem Lactose malabsorption in healthy adults.(1979-02-01) Mittal, S K; Mittal, H S; Dwivvedi, K K; Mehrotra, T N; Singh, V S; Pratap, V K; Elhence, G P; Nath, K; Shukla, S NItem Lactose malabsorption in irritable colon syndrome.(1981-09-01) Mittal, S K; Mital, H S; Dwivedi, K K; Mehrotra, T N; Kumar, M; Elhence, G P; Singh, V S; Pratap, V KItem Leucine aminopeptidase in gastrointestinal cancers.(1984-07-01) Mehrotra, T N; Singh, V S; Mital, H S; Bahadur, V; Singh, RItem Lipid profile in smokers.(1989-12-01) Rastogi, R; Shrivastava, S S; Mehrotra, T N; Singh, V S; Gupta, M KIn this study we observed that all the lipids except HDL cholesterol were higher in heavy smokers and those making for longer duration. HDL cholesterol was lower in smokers than nonsmokers. The changes in lipid profile were similar in cigarette and bidi smokers.Item Metabolic studies in subarachnoid haemorrhage.(1974-11-01) Meherotra, T N; Singh, V SItem Myoglobinuria in relation to LDH isoenzymes in acute myocardial infarction.(1984-01-01) Sehra, S; Mehrotra, T N; Goel, V K; Dwivedi, K K; Singh, V SItem Observation of lipid profile and lipoproteins in viral hepatitis and hepatic coma.(1993-10-01) Goel, V K; Mehrotra, T N; Srivastava, S S; Singh, V S; Gupta, VLipid profile and lipoprotein levels were estimated in 35 patients of viral hepatitis, 15 patients of viral hepatitis with coma and in age and sex match 35 healthy controls. The values were compared in different groups. Levels of triglycerides were significantly raised (145.00 +/- 30.70 mg/dl) in viral hepatitis as compared to viral hepatitis with coma (111.40 +/- 16.80 mg/dl) which were similar to controls (110.8 +/- 20.6 mg/dl). Patients who recovered had higher levels of triglycerides (136.0 +/- 30.8 mg/dl) as compared to those who expired (110 +/- 15.72 mg/dl). Total serum cholesterol remained statistically unaltered in both groups. HDLc was significantly decreased in both groups, viral hepatitis (2.23 +/- 6.7 mg/dl) and viral hepatitis with coma (16.52 +/- 2.27 mg/dl) in comparison to controls (62.21 +/- 18.04 mg/dl). The levels were much lower in patients with coma than without coma. Furthermore the values were still lower in patients who expired (15.82 +/- 2.27 mg/dl) than in patients who recovered (24.13 +/- 7 mg/dl). The levels of LDLc were significantly raised in both groups, as compared with each other and in relation to mortality. VLDLc levels were significantly decreased in patients of viral hepatitis (22.13 +/- 5.8 mg/dl) as well as on viral hepatitis with coma (21.89 +/- 4.3 mg/dl). However, no significant difference was observed when compared with each other and in relation to mortality. Thus it may be concluded that isolated low value of HDLc in viral hepatitis may be used as a prognostic indicator.
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