Browsing by Author "Singh, Lalit"

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    Comparative Study of Effects of Dexmedetomidine as Adjuvant to Bupivacaine and Bupivacaine Alone in Epidural Anesthesia.
    (2016-03) Singh, Vishwadeep; Singh, Geeta; Srivastava, Priyank; Singh, Lalit
    Background: Epidural anesthesia is one of the most used anesthetic technique for a lower abdominal and lower limb surgeries. Aim: The aim of the present study was to compare dexmedetomidine as an adjuvant with bupivacaine with plain bupivacaine in epidural anesthesia with respect to onset and duration of sensory and motor block, duration of analgesia, hemodynamic changes, adverse effects and sedation. Materials and Methods: A total of 60 patients of either sex with age ranging from 18 to 65 years and belonging to ASA Grades I and II physical status, scheduled for surgery under epidural anesthesia. The patients were divided into two groups with 30 patients each. Group 1 was given 20 ml 0.5% plain bupivacaine + 0.5 ml saline and Group 2 was given 20 ml 0.5% plain bupivacaine + 1 μg/kg dexmedetomidine. Results: The time of sensory onset up to T10 was shorter in Group 2 (7.10 ± 2.10 min) as compared to Group 1 (15.02 ± 2.6 min). The time of motor block onset to bromage 3 was shorter in Group 2 (14.50 ± 5.18 min) as compared to Group 1 (20.36 ± 3.4 min). The time of motor block regression to bromage 0 was longer in Group 2 (248.70 ± 28.40 min) as compared to Group 1 (152 ± 12.2 min). The time of sensory block regression and the duration of analgesia were also longer in Group 2. Conclusion: Dexmedetomidine seems to be a good choice as an adjuvant with bupivacaine in epidural anesthesia.
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    Study of Pulmonary Manifestations among Dengue Patients in Tertiary Care Hospital of North India
    (International Society for Contemporary Medical Research, 2020-05) Gupta, Samarth; Singh, Lalit; Tandon, Rajeev
    Introduction: Thoracic manifestations such as pleuraleffusion, pneumonia, and haemoptysis have been reportedin dengue infection. Dengue haemorrhagic fever (DHF) canresult in acute respiratory distress syndrome. Dengue shocksyndrome (DSS) is reported to be the third leading cause ofARDs in dengue endemic area. Current research aimed tostudy pulmonary manifestations among dengue hospitalizedpatients.Material and Methods: This study was conducted in 50patients of dengue confirmed by dengue serology. Respiratorymanifestations were recorded and all clinical examinationfindings were recovered. Baseline investigations includingcomplete blood count, liver profile, renal profile, arterial bloodgas analysis, dengue virus IgM and IgG and ns1 antigen, chestx-ray, ultrasound thorax and abdomen ultrasonography weredone.Results: Young age patients and patients with co-morbidityare risky to severe form of dengue fever and have a high riskof death. As regards co-morbidities, chronic chest disease andcardiac disease are mostly vulnerable to Dengue HaemorrhagicFever and Dengue Shock Syndrome. The most presentingrespiratory manifestations were Acute Respiratory DistressSyndrome followed by pneumonitis and pleural effusion.Conclusion: Incidence of pulmonary complications amongcases of Dengue is quite high and therefore can be used asan indicator of serious presentation of dengue in the patients.