Browsing by Author "Shipstone, A C"
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Item Asymptomatic proteinuria in children: a functional and subcellular study.(1977-08-01) Rathi, A K; Bajpai, V K; Agarwal, S K; Shipstone, A C; Bajpai, P CItem Degradation of rat liver microsomes with phospholipase 'D'.(1974-03-01) Kapoor, C L; Prasad, R; Shipstone, A C; Garg, N KItem Effect of oestrogen on the cellular structure of albino rat prostate ventral lobe.(1974-10-01) Das, A C; Saxena, R C; Beg, M A; Shipstone, A CItem Effect of phospholipase-D on rat kidney mitochondria.(1979-03) Zaidi, S N A; Shipstone, A C; Garg, N KIncubation of purified rat kidney mitochondrial fraction with phospholipase- D resulted in the accumulation of phosphatidic acid in the membrane due to the degradation of membrane-bound phosphatidylcholine, -serine and -ethanolamine Simultaneously with the hydrolysis of the phospholipids, cholesterol and protein were released from the mitochondrial membrane into the medium, and binding of Ca2+ by mitochondrial membranes increased. Phospholipase Dtreated mitochondrial fraction exhibited increased swelling in vitro in the early stages of incubation (15 min) after which the mitochondria were ruptured. Membrane- bound adenosine triphosphatase was partially inactivated and the enzyme activity was not significantly restored by incubation with sonicated dispersions of phosphatidylcholine, -serine and cholesterol. These results indicate that removal of choline, serine and ethanolamine from membrane-bound phospholipids disrupt phospholipid-cholesterol and phospholipid-protein association and affect functions of the membrane.Item Electron microscopic & biochemical study of atheromatous lesion & their prevention by reserpine.(1974-03-01) Nityanand, S; Shipstone, A C; Kapoor, N KItem Experimental evaluation of potential neurotoxicity of 4-N-butylamino 1,2,3,4-tetrahydroacridine hydrochloride (Centbucridine)--a new local anaesthetic agent.(1982-04-01) Gupta, P P; Nityanand, S; Shipstone, A C; Dhawan, B NItem Observation on the mucosa of the fallopian tube of immature rhesus monkey Macaca mulatta.(1978-12-01) Pathak, R K; Bajapi, V K; Shipstone, A C; Chandra, H; Karkun, J NItem Physiochemical alteration of surface membrane of axenic Entamoeba histolytica during repeated cholesterol passage.(1987-02-01) Gaur, A K; Bajpai, V K; Rastogi, A K; Shipstone, A C; Garg, N KItem Studies on the ultrastructure of the Fallopian tube: Part I. Changes in the ciliated cells of the rabbit Fallopian tube during ovum transport.(1974-03-01) Shipstone, A C; Bajpai, V K; Gupta, D N; Karkun, J NItem Studies on the ultrastructure of the Fallopian tube: Part II. Changes in the secretory cells of the rabbit Fallopian tube during ovum transport.(1974-03-01) Bajpai, V K; Shipstone, A C; Gupta, D N; Karkun, J NItem Ultrastructural study of epidermal Langherhans cells in leprosy.(1984-10-01) Mathur, N K; Agarwal, U S; Mukul,; Mangal, H N; Bedwal, R S; Mathur, R S; Bajpai, V K; Shipstone, A CATPase staining and ultrastructural study of skin biopsies from six patients of leprosy (2TT, 4LL) and three normal subjects was carried out to study Langherhans Cells (LC). ATPase staining showed normal counts of LCs in tuberculoid patients, while significant reduction was observed in lepromatous cases. Electron microscopy revealed morphological changes in LL cases in the form of dense matrix and indistinct cristae of mitochondria; decreased number of lysosomes and rough endoplasmic reticulum; and numerous vacuoles in cytoplasm. TT cases showed normal morphology. Possible role of Langerhans Cells in pathogenesis of leprosy is discussed.