Browsing by Author "Sharma, U K"
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Item Antenatal detection of conjoined twin.(2008-02-16) Sharma, U K; Dangol, A; Chawla, C D; Shrestha, DConjoined twin is a sporadic event with prevalence of 1 in 50000 to 1000000 birth. Incomplete division of embryonic disc results in conjoined twin. Ultrasound plays a major role for early detection and proper obstetric management. A case of cephalothoracopagus conjoined twin was detected at 20 weeks pregnancy in a primigravida woman by antenatal ultrasound. The pregnancy was terminated after proper counseling, despite the need to save the baby, as multidisciplinary team to separate the twins was not available.Item Aortic aneurysm and dissection: evaluation with spiral CT angiography.(2005-08-06) Sharma, U K; Gulati, M S; Mukhopadhyay, SThe study was undertaken for aortic evaluation and to see its usefulness for assessing aortic aneurysm, aortic dissection and pseudoaneurysm by spiral CT angiography (CTA). A total of 28 patients with aortic aneurysm (n=19), aortic dissection (n=5) and aortic pseudoaneurysm (n=4) were included. CTA findings were compared with ultrasonography in 14, digital subtraction angiography (DSA) in 14, MRI in 9; and surgical findings in 12 patients. CTA was an excellent imaging modality for comprehensive evaluation of aortic aneurysm, dissection and pseudoaneurysm combining the advantage of conventional contrast enhanced CT axial images and those of angiography in the form of 3D reformatted images.Item Breast-feeding and human immunodeficiency virus.(1997-07-01) Sharma, U K; Willingham, F FBreast-feeding provides nutritional, immunological, and psychological benefits. It protects children from mortality and morbidity associated with diarrheal diseases, pneumonia and other infections. Breast feeding has also been shown to prolong the interval between births and thereby improve child survival and maternal health. However, studies suggest that in certain populations, breast feeding may account for nearly 14% of perinatal human immunodeficiency virus type 1 (HIV-1) transmission. It is therefore important that the risk of HIV-1 infection through breast feeding be weighed against the morbidity and mortality associated with bottle feeding. This paper discusses the literature dealing with breast feeding in women with HIV-1 infection. Specifically, the review addresses the issues surrounding infant mortality in areas of different HIV-1 prevalence where breast-feeding or bottle-feeding may be employed. Analysis suggests that the benefits of breast-feeding or bottle-feeding may be employed. Analysis suggests that the benefits of breast-feeding can substantially outweigh the putative risk of HIV-1 transmission unless the prevalence of HIV-1 infection is high or the difference in mortality between breast-fed and bottle-fed infants is very low.Item Cervical spine injuries in a teaching hospital of eastern region of Nepal: a clinico-epidemiological study.(2008-02-16) Shrestha, D; Garg, M; Singh, G K; Singh, M P; Sharma, U KCervical spine injuries with neural deficits carry significant impact economically, socially and psychologically to the individual and to the society. Risk factors involved, mode of injuries, constraints of management and rehabilitation are different in developing countries. Total 149 patients of cervical spine injuries presented in B.P. Koirala Institute of Health Sciences, Dharan, Nepal were evaluated prospectively for three years. Demographic details, etiology of injury, method and time taken for transportation and treatment method and progression of recovery were recorded. Most commonly involved age group was 30-49 years (44%) with male to female ratio of 4:1. Fall related injury especially from trees was the commonest mode of injury (60%). Patients were transported to hospital without neck immobilization (81%) in a vehicle unsuitable for spinal injuries patient with average delay of two days of injury. 79% had neural deficits among which 42% are with quadriparesis, 31% are with quadriplegia. Associated extra spinal injuries were found in 9% patients. Average hospital stay was 31 days. C5 vertebra was the most commonly injured vertebra. Cervical spine injuries, which has major impact over patient and society is still not adequately addressed by medical and public health system of developing countries like Nepal. Incidence of spinal injuries and its devastating consequences can be reduced by appropriate preventive measures and management along with rehabilitation.Item Clinico-radiological profile of stroke in eastern Nepal: a computed tomographic study.(2006-04-08) Naik, M; Rauniyar, R K; Sharma, U K; Dwivedi, S; Karki, D B; Samuel, J RAIM: Stroke is a frequent cause of death and disability in elderly patients. This study was carried out to establish the pattern of various types of cerebrovascular accident (CVA) in eastern Nepal and to correlate the clinical data and radiological findings in cases of stroke. MATERIALS AND METHODS: All the patients clinically diagnosed as stroke and referred to the radiology department for Computed tomography (CT) of the brain over a period of 1 year were included. RESULTS: There were 150 patients with stroke (104 males and 46 females), aged 7 to 91 years in which infarction (58%) was more common than haemorrhage (42%) in both group of age (< or = 40 years and > 40 years). Smoking was the commonest risk factor noted in 40.66% cases followed by hypertension (40%). Excessive meat consumption (more than 4 times a week) was seen in 69.1% cases. In early Middle Cerebral Artery (MCA) territory infarction presenting within six hours of onset, positive CT findings were seen in 40% cases among which, obscuration of the lentiform nuclei was diagnostic. CONCLUSION: In this part of Nepal, infarction is more common than haemorrhage as the cause of stroke and in contrary to western population; hemorrhagic stroke constitutes a significantly higher proportion of stroke. Smoking is the commonest risk factor followed by hypertension and it is also seen in combination with alcohol in many cases. Excessive meat consumption could be an additional risk factor for stroke in this part of Nepal. In younger age group (< or = 40 years), haemorrhage is more common than infarction and alcohol consumption is the commonest risk factor.Item Effect of different levels of iron supplementation on the iron status and physical work capacity of anaemic Indian women.(1992-02-01) Dodd, N S; Sheela, T S; Sharma, U KItem Effective medical education.(2007-10-08) Sharma, U KItem Enterotoxigenicity & antibiotic resistance in salmonella strains isolated from patients of gastroenteritis.(1987-06-01) Sharma, U K; Jayasheela, M; Saxena, S NItem Entry of drugs into target tissues: antimicrobials.(1992-04-01) Sharma, U KItem Hypotensive response to repreated doses of amphetamine and mephentermine in experimental animals.(1977-01-01) Sharma, U K; Sheth, U KItem Imaging education: a radiologist's view.(2006-07-08) Sharma, U KItem Intrathyroid metastasis presenting as a solitary thyroid nodule: an unusual case of clinically silent lung cancer.(2008-01-08) Sharma, U K; Rauniyar, R K; Adhikary, S; Sinha, AMetastases in the thyroid gland are very rare. Carcinoma lung is one of the tumours, which may metastasize to the thyroid. We report a 60-year-old lady with intrathyroid metastasis presenting as a solitary thyroid nodule. Fine needle aspiration cytology from the nodule showed features of metastatic adenocarcinoma. Further detail evaluation revealed primary lung adenocarcinoma with secondaries to adrenals, retroperitoneal and bilateral axillary nodes. This report emphasizes this unusual clinical presentation of carcinoma lung with wide spread secondaries; and a solitary thyroid nodule can be a presenting complain of a metastatic disease.Item Intravesical foreign body: case report.(2006-07-08) Sharma, U K; Rauniyar, D; Shah, W FForeign bodies of the urinary bladder may occur by self insertion or migration from the neighbouring organs. All the foreign bodies when left for long act as a nidus for calculus formation. The patient usually presents with dysuria, intermittent urinary tract infection or suprapubic pain. Here we report two cases of vesical foreign body which was removed by the cystoscopy.Item Musculoskeletal ultrasound: is it underutilised?(2007-10-08) Sharma, U K; Shrestha, DItem Plasmid mediated enterotoxigenicity in Salmonella strains isolated from patients of gastroenteritis.(1987-05-01) Jayasheela, M; Sharma, U K; Mondal, A K; Saxena, S NItem Recovery of human immunodeficiency virus from asymptomatic prostitutes from Tamil Nadu.(1991-09-01) Seth, P; Sharma, U KPeripheral blood mononuclear cells (PBMC) from 13 asymptomatic healthy human immunodeficiency virus type-1 (HIV-1) antibody positive prostitutes from Tamil Nadu, southern India, were cocultivated with phytohemagglutinin stimulated PBMC from HIV antibody negative donors for HIV isolation. In addition, plasma samples from two antibody positive prostitutes with HIV antigenemia were processed for virus isolation. The presence of virus in the cultures was monitored by (i) assay for virus particle associated reverse transcriptase (RT) activity, (ii) HIV-antigen enzyme immunoassay, and (iii) indirect immunofluorescence test to detect expression of HIV specific core antigens p-24 and p-17 in infected cells using monoclonal antibodies to these antigens. The virus was isolated from PBMC from 2 prostitutes (86-4 and 86-5) and from plasma of one prostitute (86-20). These isolates have been characterised as HIV type-1 by dot blot hybridization using HIV-1 and HIV-2 proviral DNA probes.Item Roundworm infestation presenting as acute abdomen in four cases--sonographic diagnosis.(2005-01-13) Sharma, U K; Rauniyar, R K; Bhatta, NInfestation with Ascaris lumbricoides (roundworm) is very common in the tropics and subtropics. Patients with ascariasis can be asymptomatic or may present with different clinical features in the form of simple nausea, decreased appetite, abdominal pain or more severe bowel obstruction, perforation, intussusception, biliary colic etc. Ultrasonography (USG) can be quick, safe, noninvasive and relatively inexpensive tool in diagnosing the presence of worms and also evaluating response to treatment (1, 2, and 3). Here we present four cases of roundworm infestation presenting with acute abdomen in the emergency department, which were diagnosed by USG and further imaging features of ascariasis on USG is described.