Browsing by Author "Sharma, P. K."

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    Beyond the pulse: unusual presentations of Takayasu抯 arteritis
    (Medip Academy, 2024-08) Sharma, P. K.; Kumar, C.; Kumar, S.
    Takayasu抯 arteritis (TA) a.k.a pulseless disease is a chronic inflammatory occlusive thrombo-aortopathy. It is a rare inflammatory disease affecting large arteries, often leading to significant diagnostic challenges, especially when presenting with atypical symptoms. This case report explores a patient, whose primary complaints were chest pain and no neurological or constitutional symptoms, diverging from the common presentations of diminished pulses or limb claudication. Advanced imaging, including CT Aortogram and interventions like cardiac angiography, played a crucial role in detecting vascular inflammation and stenosis, facilitating accurate diagnosis and management. The case underscores the importance of considering Takayasu arteritis in differential diagnoses, even with non-classical presentations. This present case demonstrates rare and unique presentation of TA where patient presents with myocardial infarction and cardiogenic shock and also explains the diagnostic dilemma of TA with such unusual presentation.
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    Effect of Herbicides and Nitrogen Levels on Phalaris minor and Its Impact on Nutrient Uptake in Wheat (Triticum aestivum L.)
    (Ms. M. B. Mondal, 2023-04) Jeevan, N.; Singh, J. K.; Singh, M. K.; Sharma, P. K.
    In the agricultural research farm of Banaras Hindu University, Varanasi, a field research study was carried out during the winter (Rabi) season of 2018–19 to examine the impact of levels of nitrogen and herbicides on associated weeds and wheat production. Nine weed species, including Phalaris minor, Anagallis arvensis, Cynodon dactylon, Melilotus indicus, Chenopodium album, Vicia sativa, Medicago denticulata, Solanum nigrum, and Cyperus rotundus, were frequently seen infesting wheat fields. Among these, Phalaris minor was the major weed. Application of Sulfosulfuron (25 g ha-1) + 2, 4-DEE (750 ml ha-1) significantly recorded the lowest weed density and biomass and higher weed control efficiency. HW twice (30&60 DAS) in combination with 180 kg N ha-1 followed by application of Sulfosulfuron (25 g ha-1) + 2, 4-DEE (750 ml ha-1) in combination with 180 kg N ha-1 performed significantly with respect to reduction in density, the biomass of Phalaris minor, as well as increased weed control effectiveness. Nutrient uptake was significantly highest under HW twice plot (30&60 DAS) followed by application of sulfosulfuron (25 g ha-1) + 2, 4-DEE (750 ml ha-1). The overall intake of N, P, and K in wheat grain and straw increased when nitrogen levels were high (180 kg ha-1), but uptake of these nutrients was low when nitrogen levels were low, which was ascribed to reduced plant biomass (grain and straw) and a low proportion of these nutrients in the plant.
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    Effect of Integrated Nutrient Management on Growth and Yield of Barley (Hordeum vulgare L.)
    (Ms. M. B. Mondal, 2023-10) Karol, Anchal; Sharma, P. K.; Raj, Akarsha; Kehokhunu; Rawat, Anjali; Shaji, Ashline
    During the Rabi season of 2018-19, a field experiment was undertaken at Vivekananda Global University's Research Farm in Jaipur to investigate the "Effect of Integrated Nutrient Management on Growth and Yield of Barley (Hordeum vulgare L.)." The experiment followed a randomized block design with three replications. The treatments consisting of nine treatment combinations viz., 100% RDF (T1), 100% RDF + vermicompost 2.5 t ha-1 (T2), 100% RDF + vermicompost 2.5 t ha-1 + Azotobacter (T3), 75% RDF (T4), 75% RDF + vermicompost 2.5 t ha-1 (T5), 75% RDF + vermicompost 2.5 t ha-1 + Azotobacter (T6), 50% RDF (T7), 50% RDF + vermicompost 2.5 t ha-1 (T8) and 50% RDF + vermicompost 2.5 t ha-1 + Azotobacter (T9) were applied to the barley var. RD-2035. The experimental results demonstrated that several integrated nutrient treatments greatly boosted barley growth, yield characteristics and yield, quality, and economics. With the application of 100% RDF + vermicompost 2.5 t ha-1 + Azotobacter (T3), the maximum plant height at 60 DAS and 90 DAS, total number of tillers at 60 DAS and 90 DAS, effective number of tillers, ear length, number of grains ear-1, grain yield, straw yield, biological yield, and nitrogen content in grain and straw of barley were obtained. However, the application of 100% RDF yielded the significantly largest net returns and B: C ratio of barley (T1).
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    Hypertrophic pachymeningitis: a rare manifestation of IgG4 related disease
    (Medip Academy, 2023-07) Sandeepan, K.; Jha, M.; Purari, S.; Sharma, P. K.; Shreyash; Kumar, C.
    Hypertrophic pachymeningitis (HP) is a rare form of diffuse inflammatory disease that causes thickening of the dura mater. It can involve the cranial or the spinal dura or both. An increasingly well-known symptom of IgG4-related illness, a fibroinflammatory syndrome that may affect almost any organ, is IgG4-related hypertrophic pachymeningitis (IgG4-RHP). It is estimated that IgG4-RHP may account for a high proportion of cases of hypertrophic pachymeningitis once considered idiopathic. Contrast magnetic resonance imaging (MRI) shows pachymeningeal enhancement. Serum IgG4 levels may be elevated but are normal in most patients. However, most patients have elevated cerebrospinal fluid (CSF) IgG4 index. Hence, CSF IgG4 index could serve as a less invasive diagnostic marker of IgG4-RHP. Confirmation of diagnosis is by meningeal biopsy that shows swirling “storiform” fibrosis with lymphocytic infiltrates, obliterate phlebitis and IgG4 positive plasma cells. This case highlights the diagnostic dilemma of IgG4-RHP as gold standard of diagnosis is meningeal biopsy which has many of its own limitations. CSF IgG4 index could be an alternate option for meningeal biopsy when the procedure is contraindicated or uninformative.
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    The Morphologicalanalysis Of Pterion In North Indian Population
    (Era's Lucknow Medical College and Hospital, 2019-01) Yameen, Mohd.; Haider, Syed Shabeeh; Nagwani, Mumal; Munsif, Tahsin; Sharma, P. K.; Rani, Archana; Manik, Punita
    Pterion is defined as an H-shaped small circular area formed by the junction of four bones: Frontal, Parietal, Temporal and Sphenoid on Norma lateralis of the skull. A 35 dry adult human skulls of unknown sex without any gross pathology or abnormalitywere taken for the study. Sphenoparietal was the commonest type of pterion observed on both the sides. Second most common type of pterion found in our study was stellate type. Stellate type of pterion was present only on right side of skull. The accomplishments of this study contribute to anatomical variations of the pterion, which are of interest to anthropologists, forensic pathologists and surgeons. This topic of study deserves further investigation in other populations from different geographical areas.
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    The Morphologicaland Morphometric Study Of Suprascapular Notch And Its Variations
    (Era's Lucknow Medical College and Hospital, 2018-01) Vaidya, Vibhash Kumar; Srivastava, Geetanjali; Munsif, Tehsin; Tewari, Vineeta; Sharma, P. K.
    The Suprascapular notch is situated in the lateral part of the superior border of the scapula, just adjacent to the base of Coracoid process. The notch is bridged by the superior transverse scapular ligament (STSL) which some time ossifies and is attached laterally to the root of the coracoid process and medially to the limit of the notch. A number of variations occur in the shape of suprascapular notch, from a discrete notch to "J" shaped, "V" shaped, "U" shaped or "O" shaped (i.e. as a complete foramen). To study morphological and morphometric variations of suprascapular notch of Indian population. We studied 140 dried scapula bone and measurements of SSN were done using digital vernier calipers. We used the Rengachary classification for this study. The following measurements were The superior transverse diameter - maximum distance between superior most edges of suprascapular notch (SSN). The inferior transverse diameter - maximum distance between the edges of the curved arch at the base of the SSN. The results of our study were: J-shaped -28%, U-shaped-26%, V-shaped -15%, Partial-ossification-7%, Indentation-10%, Absent-9%, Complete ossification- 2%. Type IV supra scapular notch was found to be the most prevalent type amongst all shapes. We also found that the characteristics of the scapula (dimensions) are related to the characteristics of the supra scapular notch (type and dimensions) and there is a distinct difference between right and left side scapula.
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    PDA (Posterior Descending Artery) & Coronary Dominance-A MDCT Coronary Angiographic Analysis of Anatomic Variations and Clinical Importance
    (Society for Health Care & Research Development, 2018) Tomar, S; Manik, P; Sharma, P. K.; kumar, M.; Assistant Professor, Department of Anatomy, King George’s Medical University UP, Lucknow; Professor, Department of Anatomy, King George’s Medical University UP, Lucknow; Professor & Head, Department of Anatomy, Era Lucknow Medical College, Lucknow; Professor, Department of Radiodiagnosis, King George’s Medical University UP, Lucknow
    Introduction: There is considerable variation in the arterial supply of diaphragmatic surface of the heart. Diaphragmatic myocardial infarction is one of the more common consequences of coronary artery disease. The aim of this study was to assess the incidence of anatomic variants of origin and termination of Posterior Descending Artery (PDA) and to determine the type of coronary dominance in North Indian population. Subjects and Methods: This prospective study was carried out on 50 routine subjects of different age groups who came to the Department of Radiodiagnosis, King George’s Medical University UP, Lucknow in the year 2010- 2011 with known or suspected coronary artery disease. All the cases were investigated on a 64 slice Multidetector Computed Tomographic (MDCT) scanner, using retrospective Electrocardiographic gating. Endeavour was made to determine the incidence of sites of origin and termination of PDA as well as to determine the type of coronary dominance. Results: PDA arose from Right Coronary Artery (RCA) in 39 (78%) cases and from Left Circumflex (LCx) artery in 11(22%) cases. The PDA was found to terminate in the upper 1/4 of Posterior Inter-Ventricular Groove (PIVG) in 18 (36%) cases, in upper 1/2 of PIVG in 19 (38%) cases, in upper 3/4 of PIVG in 10 (20%) cases and at the apex of the heart in 1 (2%) case. None of the female had termination of PDA at the apex. Termination of PDA could not be determined in 2 (4%) cases. Right dominance was seen in 36 (72%) cases, Left dominance in 11 (22%) cases. and Co-dominance in 3 (6%) cases. Conclusion: Posterior descending artery most commonly terminated after traversing the upper half of posterior inter-ventricular groove. The incidence of left coronary dominance was more in females, it was approximately twice the incidence found in males. Co-dominance was observed only in male subjects.
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    The Study Of Nutrient Foramen Of Bones Of Arm And Forearm In Adults
    (Era's Lucknow Medical College and Hospital, 2018-01) Mishra, Anand Kumar; Jaiswal, Sonia; Sharma, P. K.; Tewari, Vineeta
    The variation in presence of number of nutrient foramen is important in long bones as nutrient foramen gives passage for entrance of nutrient arteries in to the bone. The present study was conducted on total 114 dry human long bones in department of anatomy, Era's lucknow medical college, lucknow. . The aim of the study was to determine the number of nutrient foramen in long bones of upper limb. Ethical approval was procured from the institutional ethical committee. In our study 97.40% humerus bones show single nutrient foramen, and 2.60% humerus bones show double NF, and all the radius and ulna show the single NF. The results of our study is similar with previous studies. The importance of knowledge about NF is very use full in orthopedic surgeries and in micro vascular bone grafting.