Browsing by Author "Shah, M. S."
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Item Prevalence of Risk Factors of Hypertension in Village Mirzapur, Aligarh.(2016) Ahmad, v; Faizi, N.; Shah, M. S.; Khalique, N.; Arthanari, S.; Khan, M. T.Background: The risk factors of many non-communicable diseases including hypertension are similar and include increasing age, a high salt intake, sedentary lifestyle, obesity and tobacco addiction. Due to the epidemiological transition in countries like India, many of these risk factors are on the rise. For the control and treatment of hypertension, these factors must be managed and prevented. Aim: The aim of this study is to determine the prevalence of risk factors of hypertension, and to evaluate the association between these factors and prevalence of hypertension. Materials and Methods: This was a cross sectional study, conducted in the month of December, 2015 at Mirzapur, a village in Aligarh District, Uttar Pradesh. The study population comprised of all the residents of the village ≥ 40 years of age, on the day of survey after prior consent. The data entry and other statistical calculations were done through SPSS version 20 and MS- Excel. Results: The study included 160 people above 40 years of age. The prevalence of sedentary lifestyle was 36.3%, obesity- 23.1% and average salt intake- 7.23 (2.60) grams. The tobacco addiction level, including both smoked and smokeless forms were found to be very high-45.6% in this study. Increasing age and obesity were significantly associated with hypertension. Conclusion: There is a substantial prevalence of risk factors of hypertension in India that may be the reason behind the increase in non-communicable diseases.Item Risk stratification of newly diagnosed multiple myeloma patients(Medip Academy, 2024-05) Ara Islam, I.; Samarat, M. H.; Mahzabin, N.; Jahan, N.; Akhlak-Ul-Islam, M.; Shah, M. S.; Poddar, S. C.; Reza Kabir, M. M.; Nasrin, P.; Rahman, M. A.; Akhter, N.; Afroz Chowdhury, N.; Khan, M. R.Background: Multiple Myeloma is a neoplastic proliferation of plasma cells, associated with an M (monoclonal) protein in serum and/or urine and evidence of organ damage. Despite advances in treatment, the disease remains heterogeneous, necessitating a comprehensive understanding of its risk stratification. Risk-adapted initial therapy, maintenance therapy, refractory disease management and prognosis varies according to risk group. The aim of our study is to categorize the newly diagnosed MM patients according to their risk groups. Methods: This cross-sectional observational study was conducted at the Department of Haematology of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, from August 2019 to July 2020. A total of 31 newly diagnosed MM patients were enrolled based on specific inclusion and exclusion criteria. Risk stratification was performed using ISS, R-ISS, mSMART criteria and Avets risk group categorization. Result: The majority of the patients were male (64.52%) and aged between 55-64 years (45.16%). Clinical features predominantly included low back pain (74.19%) and general weakness (38.71%). Cytogenetic abnormalities were noted in 38.7% of the patients, with del (13q) being the most common (32.30%). Most patients were in ISS Stage III (70.97%) and R-ISS Stage II (48.39%). According to mSMART criteria, 80.65% were at standard risk while Avet's risk stratification identifies 58.06% were at intermediate risk. Conclusion: The study reveals a high prevalence of patients in advanced ISS stages and intermediate to high-risk categories, emphasizing the need for early and personalized intervention strategies.