Browsing by Author "Shah, Avani"
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Item Influence of work, home and lifestyle related factors during COVID-19 lockdown on presentation of pain and functional status among school teachers with chroni non specific low back pain – An Online Survey(Portico, 2023-02) Gulati, Anisha; Sardeshmukh, Sharvari; Sawant, Suruchi; Ibrahim, Seeba Mohamed; Shah, Avani; Salunkhe, ShreeyaIntroduction: Large numbers of teachers are affected by Low Back Pain (LBP) and often report limitations in performing daily activities. The prevalence of LBP was high in the population that was confined to their houses due to COVID-19 lockdown.Objective: To study the Influence of Work, Home and Lifestyle related factors during COVID-19 lockdown on presentation of pain and functional status among school teachers with chronic nonspecific LBP.Methods: A total of 229 school teachers residing in India participated in the study. A self-administered, structured questionnaire, composed of 18 questions including various domains of life was administered; along with 13 activities of daily living and a scale to rate the difficulty level while performing.Results: Among work related activities: Prolonged sitting (p = 0.022), Gadget use (p=0.058), Twisting and turning (p = 0.035) and walking (0.036); whereas, among Home related activities: Lifting and carrying (p = 0.060) and House chores (p = 0.036) had an influence on pain. Body mass index (p=0.005) and emotional status (p=0.01) had significant correlation with intensity of pain. The most difficulty was reported in performing prolonged sitting activity.Conclusion: Covid-19 lockdown had a significant influence on work and home-related activities and lifestyle of Indian school teachers which ultimately had an effect on LBP and functional status.Item Study of parents of β-thalassemia major children to determine cutoff values of hematological parameters for diagnosis of β-thalassemia trait and assessment of anemia in them.(2013-05) Bhukhanvala, Dipal; Seliya, Vijeta; Shah, Avani; Gupte, SnehalataBackground: Because of the overlapping MCV, MCH and HbA 2 values in BTT and non-BTT subjects our laboratory determined own cutoffs. Aims: To establish cutoff values by investigating the parents of thalassemia major children and to assess the degree of anemia in BTT subjects. Materials and Methods: Study includes 179 parents of thalassemia major children (BTT cases) and 287 non-BTT controls. Samples were analyzed on an electronic hematology analyzer. The samples having MCV ≤ 76 fl and MCH ≤ 27 pg were quantified for HbA 2 by cellulose acetate electrophoresis and grey zone samples were confirmed on HPLC. Statistical Analysis Mean ± SD, sensitivity, specificity, PPV, NPV and accuracy were calculated. The histograms were plotted for MCV, MCH and HbA 2 . Results: Cases having MCV ≤ 76 fl and MCH ≤ 27 pg if considered as suspected cases of BTT then we could have missed five known BTT samples. Sensitivity increased to 100% in all three diagnostic parameters when the cutoff values were raised and specificity for MCV and MCH was decreased. But specificity was 100% with raised cutoff for HbA 2 . Hb and HCT mean values were significantly reduced in BTT cases compared to controls (P < 0.001). In 100% females and 84.9% males having BTT, mild to moderate anemia was observed. Conclusion: In our setup, the cutoff values are MCV (≤78.0 fl), MCH (≤28 pg) and HbA 2 (>3.8%) for BTT diagnosis and there is a mild to moderate anemia in BTT cases.