Browsing by Author "Saxena, K C"
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Item Action of antiamoebic drugs on hepatic microsomal drug-metabolizing enzymes of hamster infected with virulent Entamoeba histolytica.(1983-09-01) Kumar, V S; Saxena, P N; Tripathi, L M; Saxena, K C; Mohan Rao, V KItem Adaptogenic activity of Indian Panax pseudoginseng.(1989-07-01) Dua, P R; Shanker, G; Srimal, R C; Saxena, K C; Saxena, R P; Puri, A; Dhawan, B N; Shukla, Y N; Thakur, R S; Husain, AThe crude extract and saponins of Indian pseudoginseng and saponins of Korean ginseng have been studied using a battery of biological tests in rats and mice. Indian pseudoginseng saponins were found to exhibit better activity than the Korean ginseng saponins in several tests employed. The results indicate a need for in-depth study of Indian pseudoginseng as an adaptogenic agent, after cultivation of the plant under controlled conditions.Item Adjuvant activity of some nonpyrogenic hydrophobic analogues of muramyl dipeptide in enhancing the primary humoral and cell mediated immune responses in guinea pig model.(1991-02-01) Saxena, R P; Puri, A; Saxena, K C; Shukla, R; Haq, W; Rizvi, S Y; Kundu, B; Mathur, K BFive muramyl dipeptide analogues synthesized by derivatization of gamma-carboxyl of D-isoglutamine residue of MDP into alkyl amides or incorporation of lysine residue at the site via epsilon-NH2 function were evaluated for immuno-adjuvant activity. Derivatization of gamma-carboxyl of D-isoglutamine into butyl, octyl and dibutyl residues stimulated delayed type of hypersensitivity (DTH) response, the maximum stimulation being observed with octyl amide. Introduction of lauryl amide residue abolished DTH response. The antibody response was impaired with all the alkyl amide analogues except for the lysyl amide derivative with which the response was higher than MDP. Correlation was observed between DTH response and macrophage migration.Item Allergenicity of certain air-borne fungal spores of Lucknow urban area.(1978-06-01) Pathak, S K; Shukla, O P; Saxena, K C; Jamil, ZItem Animal model for testing human Ascaris allergens.(1981-03) Mukerji, Krishana; Saxena, R P; Ghatak, S N; Saxena, K CGuinea pigs immunized through the nasal route by an antigenic preparation of human Ascaris lumbricoides produced predominantly homocytotropic antibodies. The sensitization of the homologous skin required a latency period. Hypersensitivity reaction was triggered within 30 min. of the antigen challenge. The antibodies were sensitive to heat and β–mercaptoethanol treatments and appeared to be similar to the IgE type of immunoglobulins of man and rabbit. The antigenic preparation elicited an immediate type of skin hypersensitivity reaction also in human subjects harbouring the Ascaris parasite. The guinea pig model appears suitable for testing the activity of Ascaris allergens.Item Antibodies to purified protein derivative in tuberculosis patients and its relationship with pulmonary lesion.(1984-04-01) Tandon, A; Saxena, K C; Gupta, A K; Jamil, Z; Srivastava, V KItem Antibodies to purified tuberculin (PPD) in pulmonary tuberculosis & their correlation with PPD skin sensitivity.(1983-10-01) Gupta, A K; Jamil, Z; Srivastava, V K; Tandon, A; Saxena, K CItem Antibody response to TAB vaccine in human filariasis--a preliminary communication.(1981-10-01) Srivastava, V K; Saxena, R P; Bhatia, B; Tandon, A; Srivastava, B C; Saxena, K CItem Antigenic studies with Chandlerella hawkingi, the filarial parasite of Indian jungle crow, Corvus macrorhynchos.(1978-01-01) Chatterjee, R K; Tandon, A; Saxena, K C; Ghatak, S; Sen, A BItem Antigenic studies with Litomosoides carinii the filarial parasite of rodents.(1980-07-01) Tandon, A; Saxena, R P; Saxena, K C; Chatterjee, R K; Sen, A BItem Cellular immunity in Indian childhood cirrhosis.(1979-03-01) Kapoor, R K; Saksena, P N; Saxena, K C; Saxena, R P; Tolani, M KItem Cellular immunity in low birth weight infants: a preliminary study.(1981-02-01) Misra, P K; Sethi, R S; Saxena, K C; Tolani, M K; Das, KItem Dot-ELISA for diagnosis of lymphatic filariasis.(1988-05-01) Tandon, A; Murthy, P K; Saxena, R P; Sen, A B; Saxena, K CItem Effect of diethylcarbamazine on skin test & antibody response.(1983-08-01) Saxena, R P; Bhatia, B; Tandon, A; Saxena, K C; Srivastava, V KItem Galactosemia--a clinical and enzymological study in a family.(1971-12-01) Bajpai, P C; Tripathi, T K; Teotia, M; Saxena, K CItem Histopathological & enzymatic changes in guinea pig following experimental burn.(1977-01-01) Bhatia, B; Saxena, K C; Sethi, N; Sharma, R NItem Human ascaris--purification of chymotrypsin inhibitor and properties of partially purified chymotrypsin and trypsin inhibitors.(1977-11-01) Mukerji, K; Saxena, K C; Misra, P K; Ghatak, SItem Humoral immunity in Indian childhood cirrhosis.(1979-03-01) Kapoor, R K; Saxena, P N; Saxena, K CItem Immune reactivity in patients of bronchial asthma.(1981-07-01) Arshad, N; Saxena, K C; Khanna, B KItem Immune status in malnutrition.(1980-02-01) Puri, V; Misra, P K; Saxena, K C; Saxsena, P N; Saxena, R P; Agarwal, C G