Browsing by Author "Sarma, D. K."

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    Comparison Of Grace (Global Registry Of Acute Coronary Events) Score And Serum Nt- Pro BNP Level In Predicting 30 Day Mortality In Patients With Non- St- Segment Elevation
    (Indian Society for Health and Advanced Research, 2023-04) Deka, U; Das, R. P; Sarma, D. K.
    Coronary Artery Disease (CAD) is the single most frequent cause of death worldwide. More than seven million people die from CAD every year, accounting for 12.8% of all deaths. Acute coronary syndrome (ACS) is a potentially life-threatening manifestation of CAD where time is crucial in initial management. Patients with ACS are divided into two groups to facilitate evaluation and management namely acute myocardial infarction (MI) with ST segment elevation (STEMI) on their presenting electrocardiogram(ECG) and those with non ST segment elevation acute coronary syndrome (NSTE-ACS) or non ST segment elevation myocardial infarct ion (NSTEMI).The incidence of NSTEMI is rising due to the increasing burden of obesity , chronic kidney disease and increasing detection of myocardial necrosis by raised hsTrop I (high sensitive Troponin I). We aimed to explore the utility of biomarker like serum NT-pro BNP level with the Global Registry of Acute Coronary Events (GRACE) risk calculationin patients presenting with non-ST-elevation acute coronary syndromes (NSTE-ACS) .A total no 33 patients were included in this study. From the comparison of GRACE SCORE and serum NT-proBNP, the difference in 30 day mortality in patients with NSTE-ACS it had been observed that based on optimal cut off from ROC curve ,the area under the curve(AUC) for GRACE score and serum NT-proBNP were 99 vs 89.7 with a sensitivity and speci?city of 98% vs 92.86%, 94.74% vs 73.68% respectively.