Browsing by Author "Raghuveer, C V"

Now showing 1 - 20 of 41
  • No Thumbnail Available
    Item
    Benign cystic teratoma of mesentery.
    (1993-04-01) Naik, R; Raghuveer, C V
    Benign cystic teratomas are the commonest germ cell tumors in gonads but are rare in extragonadal sites and very rare in the mesentery. Herein is reported a case of primary benign cystic teratoma of the mesentery in a 10 year old girl.
  • No Thumbnail Available
    Item
    Clinical study of 100 cases of Kyasanur Forest disease with clinicopathological correlation.
    (1993-05-01) Adhikari Prabha, M R; Prabhu, M G; Raghuveer, C V; Bai, M; Mala, M A
    100 cases of Kyasanur Forest Disease were studied clinically and autopsy or postmortem biopsies of various organs were done in 8 cases. 1. Our study showed that KFD passes through 4 stages each lasting for about a week. i.e. a prodromal stage with fever, hypotension hepatomegaly, a stage of complication characterized by haemorrhage, neurological manifestation or bronchopneumonia, a stage of recovery followed by a li stage of fever in some cases. 2. The exact of cause of haemorrhage could not be identified though Disseminated Intravascular Coagulation was suspected. 3. Hypotension in KFD could be of Myocardial origin. 4. Encephalopathy in KFD could be due to a metabolic cause probably of hepatic origin. 5. Lung signs could be due to intraalveolar haemorrhage and secondary infection.
  • No Thumbnail Available
    Item
    Comparative study of peripheral blood smear, quantitative buffy coat and modified centrifuged blood smear in malaria diagnosis.
    (2008-01-18) Bhandari, P L; Raghuveer, C V; Rajeev, A; Bhandari, P D
    The present study was aimed at modifying the centrifuged blood smear (modified centrifuged blood smear or MCBS), to make it a feasible and standardized procedure. The results obtained were compared with the current diagnostic methods - peripheral blood smear (PBS) and quantitative buffy coat (QBC). Blood samples collected from 100 suspected malaria patients were subjected to all three tests. It was found that PBS had 86.79% sensitivity and was absolutely specific. QBC was 96.22% sensitive and 93.61% specific. The majority of variations occurred in PBS negative cases; cases with parasite count Plasmodium falciparum. It was seen that by the addition of centrifugation to the conventional smear technique (MCBS) improved its sensitivity from 86.79% to near 100%. QBC and MCBS were found superior to PBS. Since MCBS combines principles of both QBC and PBS, it is as sensitive as QBC, as specific as PBS, and above all, easily performed and affordable.
  • No Thumbnail Available
    Item
    Effect of N-2-mercaptopropionylglycine in limiting myocardial reperfusion injury following 90 minutes of ischemia in dogs.
    (2000-07-15) Tripathi, Y; Hegde, B M; Rai, Y S; Raghuveer, C V
    Present study was designed to examine the effectiveness of N-2-mercaptopropionyl glycine (MPG) on oxygen free radical (OFR) mediated reperfusion injury. Twenty dogs underwent 90 min of left anterior descending (LAD) coronary artery occlusion followed by 4 h of reperfusion. In control animals (n = 12), 115 ml of saline was infused through left atrium at the onset of reperfusion whereas treated animals (n = 8) received loading dose of MPG (40 mg/kg) infused through left atrium for 1 h followed by maintenance dose (25 mg/kg) for remaining 3 hours. Percentage area of necrosis vis-a-vis area at risk and percentage necrosis in left ventricular mass in MPG treated animals was significantly lower in comparison to control animals. Reperfusion in control group increased the lipid peroxidation and lowered glutathione (GSH) and superoxide dismutase (SOD) activity. MPG treatment significantly lowered the lipid peroxidation whereas GSH and SOD levels in necrotic zone were higher than in control. The above results suggest that MPG can offer a significant cardioprotection against oxidative stress in canine model.
  • No Thumbnail Available
    Item
    Effect of N-acetylcysteine and sodium nitrite on myocardial reperfusion injury.
    (1999-10-25) Tripathi, Y; Hegde, B M; Rai, Y S; Raghuveer, C V
  • No Thumbnail Available
    Item
    Effect of superoxide dismutase and acidified sodium nitrite on infarct size following ischemia and reperfusion in dogs.
    (1997-07-01) Tripathi, Y; Hegde, B M; Raghuveer, C V
    The effects of superoxide dismutase (SOD) alone or in combination with acidified sodium nitrite (NaNO2), a liberator of nitric oxide were examined in dogs after ischemia and reperfusion. Animals were divided into five groups. Left anterior descending coronary artery was occluded for 90 min followed by 4 hours of reperfusion with or without therapeutic interventions given preceding reperfusion. Left ventricular end diastolic pressure (LVEDP), left ventricular systolic pressure (LVSP) and ECG changes were monitored throughout the study. Area at risk was defined by Evans blue and area of infarction by incubation in triphenyltetrazolium. Myocardial tissue lipid peroxidation was measured in ischemic and non-ischemic zones. There was no evidence of infarction until ninety minutes of ischemia. Percentage area of necrosis vis-a-vis area at risk percentage necrosis in left vertricular mass was significantly low in animals treated with combination of SOD and NaNO2 in comparison with isolated treatment with saline, SOD or NaNO2. LVEDP increased significantly following ischemia and remained unchanged during saline reperfusion. Treatment with SOD, NaNO2 in isolation or its combination significantly lowered LVEDP. Maximum increase in tissue lipid peroxidation was observed in saline and NaNO2 treated animals. SOD alone or in combination with NaNO2 significantly lowered the lipid peroxidation. The results clearly demonstrate that reperfusion can cause necrosis in ischemic myocardium. Combined treatment with SOD and NaNO2 offers significant cardioprotection against oxidative stress.
  • No Thumbnail Available
    Item
    Endometrial aspiration cytology in dysfunctional uterine bleeding.
    (2006-04-29) Hemalatha, A N; Pai, Muktha R; Raghuveer, C V
    Aspiration cytology is a safe simple and reliable technique without any complication This can be used as a safe and reliable out patient procedure with minimum discomfort to the patient. The use of a cannula as a device for endometrial aspiration provides adequate material for cytological examination. So the present study was undertaken, to assess the ease of collection of endometrial material and to assess the relative compatibility of aspiration cytology and histopathology.
  • No Thumbnail Available
    Item
    Endomyometriosis.
    (1995-08-01) Pai, R R; Sharma, L; Pinto, P J; Raghuveer, C V
  • No Thumbnail Available
    Item
    Eruptive collagenoma.
    (2002-03-28) Mukhi, Sanjay V; Kumar, Pramod; Yuvarajkumar, D; Raghuveer, C V
    A case of eruptive collagenoma in a male is being reported. He presented with asymptomatic nodules and plaques over the trunk, upper extremity and face of 15 years duration. Family history was negative. Histopathology with H & E stain followed by Verhoeff van Gieson's staining revealed increased collagen in dermis confirming the diagnosis of eruptive collagenoma. Patient also had Beckers naevus.
  • No Thumbnail Available
    Item
    Fallopian tube prolapse following abdominal hysterectomy.
    (1995-10-01) Pai, R R; Flora,; Lobo, D; Chadaga, R P; Furtado, H J; Raghuveer, C V
  • No Thumbnail Available
    Item
    Fibrosarcomatous Bednar tumor with distant metastases--a case report.
    (2004-01-09) Kini, Hema; Raghuveer, C V; Pai, Muktha R; S, Kalpana
    In July 1994, a 27 year-old man presented with a twice recurrent, pigmented tumor on his left wrist. Wide excision and histological examination showed a pigmented dermatofibrosarcoma protuberans (PDFSP) or Bednar tumor with foci of fibrosarcomatous (FS) change. Immunohistochemistry helped to distinguish it from cellular blue nevus and malignant melanoma. In January 1997, he presented with 3 swellings on his thighs which showed features of fibrosarcoma. In March 1998, he developed multiple tumors on his thighs, chest wall, supraclavicular region, parapharyngeal region and two lung nodules. To the best of our knowledge, there are only 3 previously published reports of metastases in patients with Bednar tumor. We present the fourth such case.
  • No Thumbnail Available
    Item
    Fine Needle Aspiration cytology versus Fine Needle Sampling without aspiration. A prospective study of 200 cases.
    (2002-09-25) Raghuveer, C V; Leekha, I; Pai, M R; Adhikari, P
    In the present prospective study of 200 patients with superficial swelling of various sites, FNS followed by FNA were performed. Fifteen cases were excluded due to inadequate material. In the 80 lymph node cases, FNS was diagnostic in 85% cases as compared to FNA in 87.5%. The diagnostic accuracy was higher for FNA (87.5%) than for FNS (81.25%). However FNS smears were much superior qualitatively than FNA smears and for the diagnosis of malignant conditions FNS was found to be much better. Regarding the 68 thyroid swellings, FNS obtained a diagnosis in 82.4% cases while FNA got it in 77.9%. The diagnostic accuracy with FNS (89%) was much better compared to FNA (75%). Of the 27 breast cases FNS yielded diagnostic material in 70.38% cases while FNA was diagnostic in 85.19%, thus establishing definite superiority. However FNS seemed to be better for diagnosing malignant lesions while FNA appeared better for diagnosing benign ones. In the 5 salivary gland lesions and 5 miscellaneous lesions both FNS and FNA fared equally well. On the whole FNS technique was much more patient friendly and gave high class "text book" quality smears while FNA smears gave quantitatively more adequate material. Both the techniques therefore would be complementary to each other.
  • No Thumbnail Available
    Item
    FNAC and transabdominal ultrasonography in the diagnosis of prostatomegaly.
    (1997-10-28) Singh, N; Shenoi, U D; Raghuveer, C V
    Transrectal fine needle aspiration cytology (FNAC) was performed in 100 cases of prostatomegaly detected by digital rectal examination (DRE). The cytologic findings were compared with histolgic findings of material obtained by transurethral resection of prostate (TURP) in 84 of the cases. In addition, pre-prostatectomy transabdominal ultrasonography was done in 55 of the cases and the findings were compared with cytologic and histologic diagnoses. The accuracy of diagnosis by FNAC for benign lesions and carcinoma of prostate was 98.33% and 81.81% respectively. The accuracy of transabdominal ultrasonography for benign lesions was 91.66% but that for carcinoma was only 38.46%. The technique of transrectal FNAC was found to be simple quick, economical and easy to repeat with high accuracy and was suitable for outpatients.
  • No Thumbnail Available
    Item
    FNAC diagnosis of mucinous carcinoma of male breast--a case report.
    (2001-07-25) Nayak, S K; Naik, R; Upadhyaya, K; Raghuveer, C V; Pai, M R
    Mucinous carcinoma of the male breast is a very rare tumour. So far only about 8 cases have been reported in the literature most of which were diagnosed after surgical resection. Fine-needles aspiration biopsy even though a well established procedure for the evaluation of breast masses in female there are only occasional reports of aspirates form male breast masses. We herein-present one case of mucinous carcinoma of breast in a 65 year old male diagnosed by fine needle and confirmed by histopathology.
  • No Thumbnail Available
    Item
    FNAC diagnosis of tuberculosis--an eight years study at Mangalore.
    (1998-11-28) Bhattacharya, S; Raghuveer, C V; Adhikari, P
    1. FNAC is a very useful adjunct in the diagnosis of tuberculosis: 2. Diagnosis of tuberculosis can be made by the demonstration of epithelioid granulomas with or without caseation even in the absence of AFB. 3. Necrotic features whether acellular or accompanied by neutrophilic infiltrate are usually misdiagnosed as suppurative abscesses. Such smears however show high AFB positivity and thus the diagnosis of tuberculosis is still possible even in the absence of epithelioid granulomas. 4. Therefore all smears obtained by FNAC of suspected tuberculous lesions should be subjected to ZN staining for AFB.
  • No Thumbnail Available
    Item
    Giant adrenal cysts.
    (1994-12-01) Sahu, K K; Pai, R R; Raghuveer, C V
  • No Thumbnail Available
    Item
    Hyperreactio luteinalis.
    (1996-04-01) Raghuveer, C V; Pai, R R
  • No Thumbnail Available
    Item
    Isolated right atrial infarction in a patient with corpulmonale. A clinicopathological report.
    (1997-03-01) Adhikari, M R; Raghuveer, C V; Shenoi, U D; Pratibha, P
  • No Thumbnail Available
    Item
    Mast cell profile in prostatic lesions.
    (1998-11-28) Amir, T; Pai, R R; Raghuveer, C V
    Mast cell profile in common prostatic lesions was analysed in this study. 17B consecutive prostatic biopsy specimens specimens were categorised broadly into nodular hyperplasia without prostatitis (101), nodular heperplasia with prostatitis (50, prostatic intraepithelial neoplasia (2) and adenocarcinoma (25). Toluidine blue stain (0.1%) was used to demonstrate the mast cells and their count was expressed per square millimeter. Mast cell count was significantly higher in the fibromuscular stroma when compared to the glandular areas in nodular hyperplasia (p < .05). The mast cell counts were very significantly lower in inflammatory lesions (p < 0.0001) probably due to degranulation. Absence or a low count was the most significant finding in adenocarcinoma irrespective of the grade of the tumour with concentration of mast cells around the tumour. This study shows the variations in mast cell distribution in commonly encountered prostatic lesions. There is paucity of such studies in the literature and the possible utility of mast cell count to differentiate malignant from benign and atypical conditions needs further evaluation.
  • No Thumbnail Available
    Item
    Multiple meningiomas--a case report.
    (1996-12-01) Bansal, R; Raghuveer, C V; Pai, R