Browsing by Author "Raghupathi, A R"

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    Bone marrow changes in elderly.
    (2015-04) Sulakshana, M S; Ahmed, S M; Raghupathi, A R
    Aim: To study the bone marrow changes in elderly patients (above 60 years of age). Material and methods: Bone marrow records from the pathology laboratory in the Department of Pathology, Bangalore Medical College, Bangalore, from March 2012 to june 2013, were searched, and cases from all patients at least 60 years old at the time of bone marrow study were retrospectively reviewed. Results: During the 16 months period, 164 bone marrow examinations were performed, andout of these, 50 patients were at least 60 years old. The age range of the patients was 60 to 82 years , 27 were males and 23 were females. 47 cases (94%) yielded specific diagnosis. 27 cases (54%) had nutritional anemia, 6 cases (12%) were diagnosed as myeloma, 3 cases (6%) had aplastic anemia, 3 cases (6%) had chronic lymphocytic leukemia/ small lymphocytic leukemia infiltrating the bone marrow; 2 cases (4%) had acute myeloid leukemia, 2 myelofibrosis - grade 3, 2 cases were diagnosed to have monoclonal gammopathy of undetermined significance (4%), 1 case (2%) had metastatic deposits from prostatic carcinoma and 1 case (2%) of mylodysplastic syndrome - refractory cytopenia with multi lineage dysplasia and ringed sideroblasts was diagnosed. Conclusions: In this study we found that after nutritional anemia, plasma cell dyscrasias were the most common findings in bone marrow studies in elderly patients. Diagnosis of plasma cell dyscrasias prompt for early institution of treatment resulting in reduced morbidity and mortality in such patients.
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    Carcinoma within a fibroadenoma: a case report.
    (2006-10-23) Hemalatha, A L; Raghupathi, A R; Karthikeyan, T M; Kumar, Deepak B; Shashidhar, H B
    Carcinoma within a fibroadenoma is an extremely rare occurrence with a reported incidence of 0.1% and is most often diagnosed incidentally on post-operative examination of excision biopsy specimens. One such case is reported here for its rarity and also for stressing upon the need for compulsory excision of all breast masses clinically diagnosed as fibroadenoma and for highlighting the importance of histopathological evaluation of all breast masses irrespective of their clinical diagnosis as benign.
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    Giant cell tumor of skin.
    (2006-03-19) Sunil Kumar, Y; Raghupathi, A R; ,
    Giant cell tumor of the skin is a rare entity showing gross and histological features similar to those of giant cell tumor of the bone. We report a case of malignant giant cell tumor of the thigh in a 55-year-old man. Histological features showed a biphasic population of mononuclear cells admixed with osteoclast-like giant cells. The nuclei of the giant cells were similar to those of the mononuclear cells. This tumor should be distinguished from a variety of cutaneous neoplasms that contain multinucleated giant cells.