Browsing by Author "R. Ravindran"

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    The Role of Sympathetic Skin Response in Assessing Autonomic Function in Normal Adults
    (Sumathi Publications, 2023-03) R. Ravindran; Iyer Saraswati; Deshpande Mangala
    Background:Sympathetic Skin Response (SSR) is a simple, non-invasive and reproducibletest to assess the impairment of the sympathetic fibers of the peripheral nerves. It measuresthe change in electrical skin potential to a variety of stimuli. The objective of this study was toassess SSR in a sample of normal healthy adults.Method:25 normal healthy adults whovolunteered to participate were assessed for SSR in their foot and hand. SSR was assessedusing Neurowerk EMG/NCV equipment capable of assessing SSR. Electrical current was usedon the median nerve at the wrist to elicit SSR.Results:SSR was elicited in all 25participants. The mean SSR latency and SSR Amplitude for the hand were 1.2 (+/- 0.42) secsand 2503 (+/- 1424) micro Volt respectively. The mean SSR Latency and SSR Amplitude forthe foot were 1.8 (+/- 0.44) secs and 1749 (+/- 1252) micro Volts respectively. It was observedthat there was no significant difference in the SSR values when compared between male andfemale participants, so gender had no effect on SSR values. There was no association of SSRvalues with the BMI of the participants. Characteristics of the SSR curves were discussed.Conclusion:Mean values of SSR latency measured at hand and foot are 1.2 (+/- 0.42) secsand 1.8 (+/- 0.44) secs respectively. Mean values of SSR amplitude measured at hand and footare 2503 (+/- 1424) micro Volts and 1749 (+/- 1252) micro Volts respectively. Gender had noeffect on SSR values in this study.
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    A Study of Sympathetic Skin Response inpersons with Type-2 Diabetes Mellitus
    (Sumathi Publications, 2024-03) R. Ravindran; Iyer Saraswati; Deshpande Mangala
    Background: Impairment in Autonomic nervous system constitutes to one of the most serious and important complications in persons with Diabetes. Noninvasive Sympathetic Skin Response (SSR) test assesses the impairment of the sympathetic fibers of the peripheral nerves is widely used and valid markers of autonomic neuropathy. Considering the cost effectiveness of these tests, SSR testing would help us in understanding the prevalence of autonomic dysfunction in patients with Type 2 Diabetes Mellitus (T2DM). Method: 30 adults diagnosed with T2DM and 25 normal healthy adults who volunteered to participate were assessed for SSR in their foot and hand. SSR was assessed using Neurowerk EMG/NCV equipment capable of assessing SSR. Electrical current was used on the median nerve at the wrist to elicit SSR. Results: SSR was elicited in all participants. In persons with T2DM, mean SSR latency and SSR Amplitude for the hand were 1.587 ± 0.759 secs and 1499 ± 1411 microVolt respectively. The mean SSR Latency and SSR Amplitude for the foot were 2.478 ± 1.247 secs and 39.2 ± 901.07 micro Volts respectively. Characteristics of the SSR curves were discussed. Conclusion: In persons with T2DM, mean SSR latency of hand and foot were 1.587 ± 0.759 and 2.478 ± 1.247 seconds respectively. Mean SSR amplitude of hand and foot were 1499 ± 1411 and 939.2 ± 901.07 microVolts respectively. Mean values SSR Latency & Amplitude of persons with T2DM were significantly different from that of normal healthy adult.