Browsing by Author "Puri, R"
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Item Bartter抯 syndrome type II due to a novel mutation in KCNJ1 gene presenting in adulthood as recurrent hypokalaemic periodic paralysis(Medip Academy, 2024-10) Kandari, S; Puri, R; Cheluvaiah, C; Biswal, A; Singh, A; Ahlawat, P.Bartter抯 syndrome affects salt reabsorption transporters in Henle's loop's thick ascending limb (TAL). Bartter抯 syndrome type II begins in antenatal/neonatal period with an autosomal recessive pattern of inheritance due to mutation in the KCNJ1 gene. Renal disorder begins early. It is a disorder which usually presents in infancy but not in adulthood. We report a case of late onset Bartter抯 syndrome type II due to a novel mutation in the KCNJ1 gene manifesting with bilateral medullary nephrocalcinosis and recurrent hypokalaemic periodic paralysis.Item A case report of thrombotic microangiopathy in a patient with advanced pancreatic carcinoma: an emerging, rare, and serious complication(Medip Academy, 2025-06) Kandari, S; Singh, A; Puri, R; Cheriyan, A; Kaur, SThrombotic microangiopathies are characterized by microangiopathic hemolytic anemia and end-organ damage following endothelial injury. The chemotherapeutic agents used in malignancy are one of the important causes of secondary TMA. Both malignancy and TMA are associated with significant morbidity and mortality. Timely recognition of both can result in early target-specific treatment initiation and better outcomes for both diseases. Here, we present a case of TMA in a patient with stage 4 pancreatic carcinoma being treated with Gemcitabine presented with acute kidney disease with new-onset hypertension, edematous illness, and anemia. The patient was Hemodialysis dependent and was treated with steroids, plasma exchange, and rituximab. The patient remained HD dependent 6 months post-treatment and was declared ESRD. Highlighting the importance of early recognition and timely treatment initiation.Item Efficacy of nimesulide alone and in combination with cetirizine in acute allergic rhinitis.(2001-05-22) Kotwani, A; Puri, R; Gupta, UOBJECTIVE: To study the effect of cetirizine and nimesulide given alone and in combination in allergic rhinitis. METHOD: A double blind, double dummy, randomised, parallel controlled clinical study in three groups consisting of 18 patients each suffering from allergic rhinitis was conducted. Group A was given nimesulide alone (100 mg BD), Group B received combination (nimesulide 100 mg + cetirizine 10 mg) and Group C was given cetirizine alone (10 mg) for one week. The efficacy of each treatment in reducing nasal stuffiness, nasal discharge, itching nose and watery eyes was assessed at base line (day 0), on days four and eight of treatment. Patients used diary cards twice daily to rate symptom severity on a four point scale. RESULTS: Nimesulide and cetirizine alone could decrease nasal discharge, nasal stuffiness and sneezing significantly in allergic rhinitis patients by day four. Cetirizine was more effective in relieving nasal discharge and sneezing compared to nimesulide. By combining cetirizine and nimesulide four symptoms of allergic rhinitis, i.e., nasal discharge, nasal stuffiness, sneezing and watery eyes decreased significantly. CONCLUSION: Present study has shown that nimesulide alone could decrease three symptoms of allergic rhinitis like certirizine and combination of cetirizine (anti-histaminic) and nimesulide (anti-inflammatory) exerts synergistic action in reducing symptoms in patients of allergic rhinitis.Item Efficacy of nutrition and health component of the Bal-Sevika (pre-school teachers) training programme.(1988-10-01) Puri, R; Mehta, SItem An evaluation of the pre-school supplementary feeding programme in Chandigarh.(1983-05-01) Chawla, P; Puri, RItem Feeding practices among children of different castes in rural Ludhiana.(1983-07-01) Kaur, S; Puri, R; Bajaj, SItem Impact of an on-going supplementary feeding programme on the mental abilities of children.(1984-11-01) Puri, R; Chawla, P; Sharma, M; Pershad, DItem Impact of nutrition and health education on rural pre-school children.(1994-01-01) Puri, R; Mehta, SPre-school children (n = 155) belonging to low socio-economic group from eight creches in villages around Chandigarh, were imparted nutrition and health education (NHE) for one year. Appropriate teaching material in the form of songs, rhymes and roleplays were scientifically developed for the purpose. For impact evaluation, objective tools in the form of checklists were formulated and used. NHE on three aspects, i.e., personal hygiene (PH), food hygiene (FH) and recognition of foods (RF) was imparted by Balsevikas (BSs) incharge of the creches, daily in a non-formal manner, for one year and evaluated periodically. On PH only, children of the lowest income group improved significantly. On FH and RF, all children registered significant improvement as these two aspects, were under the direct control of BSs who enthused and involved the children by providing an interacting and stimulating environment. The results are encouraging and indicate the pre-school children are educable in NHE provided participatory and appropriate material and methods are used.Item Impact of nutritional supplements on hematological profile of pregnant women.(1995-08-01) Chawla, P K; Puri, REighty one pregnant women (20 +/- 2 weeks of gestation) were assessed for their nutritional status. They were divided into three groups; Group I women (n = 30) were given 200 mg ferrous sulphate (FeSO4) tablet per day for 15 weeks, Group II women (n = 25) were given FeSO4 tablets along with 2,000,000 IU of vitamin A as single dose in beginning of study; and Group III women (n = 26) were not given any supplements and served as controls. To study impact of supplements on hematological profile of pregnant women, Hb, PCV, RBC, TS%, TIBC and serum levels of iron, zinc, copper, manganese and vitamin A were assessed at 20 +/- 2 weeks and 36 +/- 2 weeks of gestation by standard techniques. Pregnant women in Group I (Fe suppl) and group II (Fe + vitamin A suppl) had significantly (p < 0.01) higher Hb, PCV, RBC, TS% and serum iron levels than the controls. Group II had significantly (p < 0.05) higher values of these indices as compared to Group I. Levels of serum zinc, copper, manganese were not affected by supplements. Iron supplements improved the hematological profile of pregnant mothers but Fe + vitamin A supplements were more beneficial.Item Impact of pre-school supplementary feeding on clinical picture.(1983-07-01) Chawla, P; Puri, RItem Impact of pre-school supplementary feeding on mental abilities.(1983-07-01) Chawla, P; Puri, R; Pershad, DItem Impact of pre-school supplementary feeding programme on anthropometry.(1983-05-01) Chawla, P; Puri, RItem The incidence of allergic diseases and feeding patterns in children upto 2 years of age.(1984-01-01) Parihar, H; Kumar, L; Puri, R; Kumar, VItem Pancreatic tuberculosis.(1997-04-01) Bhargava, N; Shah, P K; Lakhotia, M; Puri, RItem Paroxysmal nocturnal hemoglobinuria presenting as acute renal injury(Medip Academy, 2024-09) Saini, S; Koley, H; Dhoot, DK; Cheluvaiah, C; Puri, R; Karunanidhi, DS; Jatteppanavar, B; Biswal, A; Ahlawat, P.Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired chronic hemolytic anemia characterized by persistent intravascular hemolysiswith occasional or frequent recurrent exacerbations. In addition to hemolysis, there may be, pancytopenia and a distinct tendency to venous thrombosis. This triad makes PNH a truly unique clinical condition; however, not all of these three features manifest on presentation. Not many reports of renal involvement in PNH are available in the literature. We report a case of acute kidney injury (AKI) due to PNH. This case shows AKI as one of the complications of PNH.Item Pre-school teachers (Balsevikas) in-service orientation in nutrition and health education--an impact study.(1988-07-01) Puri, R; Mehta, SItem A randomised double blind cross over trial of atenolol and propranolol in mild to moderate hypertension.(1987-06-01) Mahajan, V; Puri, R; Gattani, R K; Chatterji, TItem Serum cortisol [correction of control] following replacement therapy in Triple A syndrome.(1999-04-16) Puri, R; Goraya, J SItem Taste sensitivity in pregnancy.(1991-04-01) Bhatia, S; Puri, RTaste sensitivity to Phenyl-thio-Carbamide (PTC) and glucose were studied in 150 females during the 3 trimesters of their pregnancy periods. The taste sensitivity to PTC was determined by Harris and Kalmus method. For taste intensity and hedonic evaluation, 7 concentrations of glucose solutions were used. Taste sensitivity to both PTC and glucose increases during the 1st trimester of pregnancy. In comparison to non-pregnant females (from previous study) taste thresholds and hedonics decreases in pregnancy.Item Top-of-the-basilar-artery stroke.(2001-01-15) Mitra, S; Ghosh, D; Puri, R; Parmar, V R