Browsing by Author "Pawar, Sunil"
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Item Bilateral Dupuytren’s Contracture.(2014-02) Redkar, Neelam; Pawar, Sunil; Patil, Meenakshi; Mahajan, Sameer; Keur, AjayDupuytren’s contracture (DC) is painless flexion contracture of ulnar side of palm where fingers bend towards palm and cannot be straightened. It is a fibrosing disorder that results in slowly progressive thickening and shortening of the palmar fascia, leading to the debilitating digital contractures. The prevalence of DC is found to be higher in patients with cirrhotic or noncirrhotic alcoholic liver disease. We report the case of a 56-year-old male chronic alcoholic who presented with distention of abdomen, yellow discoloration of sclera since 1 month and altered sensorium since 1 day. He had bilateral contractures on ulnar side of hands, suggestive of DC.Item Different methods of formulation and evaluation of mucoadhesive microsphere.(2010-11) Parmar, Harshad; Bakliwal, Sunil; Gujarathi, Nayan; Rane, Bhushan; Pawar, SunilMucoadhesion is topic of current interest in the design of drug delivery system. Mucoadhesive microsphere exhibit a prolonged residence time at the site of application and facilitate an intimate contact with the underlying absorption surface and thus contribute to improved or better therapeutic performance of drug. Mucoadhesive drug delivery systems promises several advantages that arise from localization at a given target site, prolonged residence time at the site of drug absorption and an intensified contact with the mucosa increasing the drug concentration gradient. Hence, uptake and consequently bioavailability of the drug is increased and frequency of dosing reduced with the result that patient compliance is improved. In recent years such Mucoadhesive microspheres have been developed for oral, buccal, nasal, ocular, rectal and vaginal for either systemic or local effects. The principles underlying the development of Mucoadhesive microsphere and research work carried out on these systems are reviewed here.Item A rare case of paediatric trichotillomania complicating into Rapunzel syndrome: a case report(Indian Psychiatric Society, 2014-07) Bollapalli, Preethi Swaroop; Bommakanti, Janardhan; Vangala, Sravan Reddy; Pawar, Sunil; Reddy, MadhumohanBackground: Trichotillomania is a psychological condition that involves strong urge to pull one’s hair. Trichophagia is disorder of eating of hair. Bezoar is collection of undigested material such as hair, drugs and plastic or combinations. Rapunzel syndrome is a rare type of trichobezoar, which has mass of hair lodged in stomach extending up to ileum. In majority, diagnosis is made very late, at a stage where surgery is the only option. Case description: A 9 year old girl was brought with complaints of loss of hair on scalp since 8 months, decreased appetite, and constipation, weight loss since 5 months and vomiting since 2 weeks. Patient had paediatric consultations without much benefit; patient was referred to dermatologist and paediatric surgeon. Ultrasound showed mass in abdomen. Patient was operated to find a mass extending from stomach to terminal ileum. Patient was referred to a Psychiatrist and diagnosis of Trichotillomania was made. Discussion: Trichobezoar is common in young females, often with an underlying psychiatric disorder, they present late due to the low index of suspicion. As this condition is a rarity in paediatric age group and very little progress to Rapunzel syndrome, this paper discusses about the systemic team management of the above individual. Conclusion: High index of suspicion is needed to diagnose this condition in paediatric age group.Item Wiser to prevent childhood obesity.(2016-03) Rathi, Pravin; Pawar, Sunil; Contractor, Qais