Browsing by Author "Paul, S."

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    Association between neutrophil to lymphocyte ratio with the severity of coronary artery diseases
    (Medip Academy, 2023-09) Das, S.; Das, P. K.; Awal, A.; Bin Latif, S.; M. Ismail, K.; Hossan, M. S.; Siddike, S.; Paul, S.; Bashiruddin, M. A. B. K.; Bhattacharyya, P.
    Background: Coronary artery disease is a type of heart disease where the arteries of the heart cannot deliver enough oxygen-rich blood to the heart. This study aimed to evaluate the association between neutrophil to lymphocyte ratio (NLR) with the severity of coronary artery diseases. Methods: This cross-sectional study was conducted in the Department of Cardiology, Chittagong Medical College Hospital, Chattogram, Bangladesh during the period from 1 July 2020 to 31 June 2021. 160 patients undergoing elective coronary angiography with the symptoms of coronary artery disease were enrolled in this study. A purposive sampling technic was used. The association between NLR and Gensini score was assessed using Pearson’s or Spearman’s correlation analysis as appropriate. All data were processed, analyzed and disseminated by using MS Excel and SPSS version 23.0 program as per necessity. Results: The mean (±SD) Gensini score of our participants was 42.75 (±29.50) and the mean (±SD) NLR (Neutrophil-lymphocyte ratio) was 2.38 (±1.11). In this study, the AUROC for NLR was found as 0.851 with a P-value of <0.001, indicating a statistically significant association of NLR with the severity of CAD. The scatter dot diagram showed the correlation between NLR and Gensini score. Both the variables were positively correlated and the degree of correlation was found statistically significant (r=0.44; p<0.001) by Pearson’s correlation test. The multivariate logistic regression analysis showed that a high level of NLR had an independent association with severe CAD (with OR being 3.308) along with dyslipidemia. Conclusion: High blood NLR is associated with the severity of CAD and it may be useful for predicting angiographically severe disease.
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    Beyond the ‘tic’ king clock: a case report on adult onset tic disorder
    (Medip Academy, 2024-06) Bose, A.; Nandi, S.; Sarkar, A. K.; Paul, S.; Roy, S.; Baidya, S.
    Tic is rapid recurrent non-rhythmic motor movement or vocalization; movement of limbs or other body parts is known as motor tic and involuntary repetitive sound like grunting sniffing throat clearing is known as a vocal tic. Tic is a neurodevelopmental disorder and has its onset in the developmental period. According to diagnostic and statistical manual of mental illnesses (DSM) 5, tic should have its onset before 18 years of age and can resolve with proper treatment. In this case, a 23-year-old female presented with recurrent abnormal throat clearing and excessive loud sounds which started for the last 1 year. Initially, she was diagnosed with psychogenic hiccup in another department and was treated with Baclofen 30 mg for 1 month but as no improvement was observed later she was referred to psychiatry outpatient department (OPD) for further treatment where she was diagnosed with adult onset vocal tic with a premonitory urge for tics scale (PUTS) score of 27 on admission and she was treated with tablet Risperidone 2 mg and after 4 weeks of treatment all symptoms subside and PUTS score came to be 6 at the time of discharge.
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    Coinfection of genital herpes simplex virus with human immunodeficiency virus and hepatitis B virus infection- a case report
    (Medip Academy, 2024-11) Datta, K; Chanda, DD; Paul, S.
    A rare case of coinfection with 3 viral sexually transmitted infections (STIs) namely Human immunodeficiency virus (HIV), Hepatitis B virus (HBV) and Herpes Simplex virus 2 (HSV 2) is presented here. Although this type of simultaneous coinfection is rare but is not impossible, as all of them share similar routes of transmission and they augment each other抯 risk of transmission either by immunosuppression or by increasing viral shedding.
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    Numbness and bleeding from the ear following inferior alveolar nerve block: report of a case
    (Medip Academy, 2023-12) Das, J. R.; Vinod Vichattu, S.; George, A.; James, J. E.; Paul, S.
    The inferior alveolar nerve block is a Mandibular nerve block given to anesthetize the mandibular teeth. Due to its proximity to other nerves and muscles and salivary glands it has many complications if the technique in which it is given is wrong. IANB usually presents with mild or minimal complications following it’s administration. The complications that arise are usually reversible when the action of the local anaesthetic wears off. These complications are usually associated with improper technique and anatomical variations, which can be rectified there itself with slight modifications. This is a very rare complication which has been reported where the patient has experienced numbness of the auricle on the side of inferior alveolar injection which lasted for an hour. This is seen due to the accidental anesthetic injection to the auriculotemporal nerve resulting in numbness. To perform successful inferior alveolar nerve blocks it is mandatory to be familiar with anatomical landmarks. Proper technique can reduce the complications.
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    Prediabetes, dyslipidemia and c-reactive protein levels among stroke patients: a hospital-based study in north-east India
    (Medip Academy, 2023-01) Das, M.; Paul, S.; Roy, S.
    Background: Stroke is defined as an abrupt onset of a neurologic deficit lasting for more than 24 hours that is attributable to a focal vascular cause. Hyperglycemia and dyslipidemia are often documented in stroke patients. Elevated CRP level is independently associated with the excessive risk of ischemic stroke. Aim and Objectives were to evaluate the glycemic status, lipid profile and c-reactive protein level in stroke patients admitted in a teaching institute of north-east India. Methods: A cross-sectional hospital-based study conducted in the department of medicine, Agartala Government Medical College and GBP hospital, within a period of January 2020 to June 2021. Data were analyzed by SPSS software version 15 using appropriate statistical tests. Results: Among 200 patients of stroke, 50% was found to be pre-diabetic, 40% known diabetic and 10% newly diagnosed diabetic. 60% were hypertensives. Among them, 80% had ischaemic stroke and 20% hemorrhagic stroke. 70% of the patients had hypercholesterolemia, 60% had hypertriglyceridemia. 80% had raised serum LDL and 57% decreased serum HDL. Out of 200 patients, 60% was found to have raised serum CRP level. 55% of ischaemic stroke patients and 5% of hemorrhagic stroke patients had raised CRP level. Conclusions: Prediabetes and newly diagnosed diabetes are highly prevalent in patients with stroke or TIA. As the prevalence of prediabetes is growing rapidly, prediabetes might become one of the most important modifiable therapeutic targets in both primary and secondary prevention. Early detection of dyslipidemia and treatment with drugs along with dietary modifications and lifestyle changes can reduce the risk of stroke. Since, it was a cross-sectional study, these results need to be validated by further long-term prospective studies.