Browsing by Author "Oza, Y K"
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Item Depression--an adverse event with nifedipine.(2002-11-14) Patalia, A H; Rathod, N R; Gandhi, R R; Gohel, D R; Oza, Y KTwo cases are reported in which depression was associated with the use of calcium channel blocker, nifedipine. In one instance, a patient became unresponsive to treatment with nortriptyline when nifedipine was introduced. In both cases, the depression resolved following discontinuation of nifedipine.Item Infections via respiratory equipment: a potential hazard.(1993-04-01) Oza, Y KItem An open clinical trial of benazepril--a new ACE inhibitor in mild-moderate hypertension.(1998-03-29) Karnik, N D; Oza, Y K; Sane, S P; Kaushik, R; Bhatt, A D; Chawla, K P; Vaidya, A B; Yajnik, V H; Khokhani, R CBenazepril hydrochloride, a new non-sulfhydryl ACE inhibitor (ACEI) was studied in a titrated dose of 10 mg-20 mg once a day for 6 weeks in 42 mild to moderate adult hypertensive patients with sitting diastolic blood pressure (SDBP) 95-114 mm Hg. The pre-drug SDBP(mean +/- SE) of 102.5 +/- 0.8 mm Hg showed a significant reduction to 87.5 +/- 0.93 mm Hg at the end of treatment. BP was controlled (SDBP < or = 90 mm Hg) in 34 (81%) patients and a drop of at least 10 mm Hg from the pre-treatment SDBP value was noted in 34 (81%) patients. Common adverse reaction was cough in 8(19%) patients. Clinically significant changes in laboratory evaluations were not seen in any patient. Study showed that benazepril in a dose range of 10 to 20 mg per day is an effective agent for treatment of mild to moderate hypertension.