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  1. Home
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Browsing by Author "Nandhini, M"

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    Chiari 1.5 malformation: a case report and review of literature
    (Medip Academy, 2025-06) Selvan, R; Pandey, N; Nandhini, M; Hrishikaanthan, SS.
    Chiari 1.5 malformation, a rare neurological disorder, involves cerebellar tonsil herniation and slight brainstem descent through the foramen magnum. A 25-year-old woman presented with recurrent headaches exacerbated by coughing, straining, and difficulty in maintaining head posture despite normal motor functions and reflexes. MRI revealed a Chiari 1.5 malformation with a 13.5 mm cerebellar tonsil herniation, minor brainstem descent, and C2-C3 vertebrae fusion. Suboccipital craniectomy with foramen magnum decompression significantly alleviated her symptoms. This case emphasizes the importance of recognizing Chiari 1.5 malformation as a cause of headaches in young adults and supports surgical intervention to prevent neurological decline. Although the aetiology is unknown, theories suggest a pressure differential between the cranial and spinal subarachnoid spaces during fetal development. Early diagnosis and posterior fossa decompression are crucial for symptom management and outcome improvement in CHIARI 1.5.

IMSEAR is the collaborative product of Health Literature, Library and Information Services (HELLIS) Network Member Libraries in the WHO South-East Asia Region.
HELLIS is coordinated by WHO Regional Office for South-East Asia.

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