Browsing by Author "Nahta, Pintoo"

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    Assessment of Serum Uric Acid in Patients of Acute MI: Clinical Importance
    (Ibn Sina Academy of Medieval Medicine & Sciences, 2019-01) JaipalBugalia; Gupta, Himanshu; Choudhary, Dinesh; Budhania, Sunil; Nahta, Pintoo; Acharya, Jitendra
    Introduction: MI (Myocardial Infarction) remains an importanthealth problems. Various studies have recently found that uricacid may be a risk factor for cardiovascular diseases and anegative prognostic marker for mortality in subjects with preexisting congestive heart failure. Elevated serum uric acid ishighly predictive of mortality in patients with heart failure orcoronary artery disease and of cardiovascular events inpatients. Many studies including the National Health andNutrition Examination Survey (NHANES) study concluded thaturic acid is an independent risk factor for development ofcardiovascular and cerebrovascular diseases.Objective: To observe uric acid levels in patients with acutemyocardial infarction.Methodology: It was a hospital based observational studyperformed from January 2017 to July 2017 at Department ofCardiology, S. P. Medical College, Bikaner (Rajasthan) inwhich 75 patients was enrolled. Patients more than 18 years ofage diagnosed to have acute MI who presented to hospitalwithin 24 hours of onset of symptoms were included in thestudy, while patients with condition known to elevate UA (UricAcid) levels or patients receiving drugs affecting serum UAlevels & chronic alcoholics’ patients were excluded. Statisticalanalysis was done by software.Results: Patients of higher age with AMI had higher uric acidlevel as well as those who had previous history of MI hadhigher uric acid levels. Patients with AMI who died duringhospitalization had higher uric acid levels compare to alivepatients.Conclusion: SUA (Serum Uric Acid) can be used as a markerfor increased risk of acute MI. Furthermore, SUA can also beused for risk stratification after acute MI.
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    Vitamin D Estimation: A New Biomarker for Cardiovascular Disease
    (Ibn Sina Academy of Medieval Medicine & Sciences, 2018-04) Pandey, Umesh Kumar; Agarwal, Arpit; Mehla, Rakesh; Choudhary, Dinesh; Nahta, Pintoo; Agarwal, Devendra
    Background: Vitamin D deficiency is prevalent in the majority parts of the world. The prevalence of vitamin D deficiency in India in urban area 9-11% and in rural area 3-6%. Coronary artery disease is worldwide health problem and consists of variety of heart illness. Vitamin D deficiency may cause cardiovascular events by a variety of potential biological mechanism. Aims & Objectives: To evaluate the role of vitamin D as a rising risk factor for coronary artery disease.  Materials & Methods: The study was carried out in department of Cardiology, S.P. Medical College included 50 patients of coronary artery disease admitted in H.R.M. Center Bikaner. The control population comprise of age and sex matched 50 healthy persons. Vitamin D was done on ELISA reader and lipid profile assessment was done on fully automated analyzer. The statistical analysis was done by using SPSS software. The results were articulated as Mean ± SD. The Student t-test was carried out for relationship of the data & P value <0.05 was considered statistically significant. Results: The study discovered that vitamin D level was established to be significantly lower in cases as compared to controls. We also noticed significant difference in mean to total cholesterol, HDL cholesterol and LDL cholesterol in between cases and control. Conclusion: This study concluded that continue follow up of vitamin D will be helpful for measurement of increased risk of coronary artery disease episode beyond the traditional risk factors.