Browsing by Author "Murthy, R"
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Item Botulinum toxin in ophthalmic plastic surgery.(2005-12-08) Naik, Milind N; Soparkar, Charles Ns; Murthy, R; Honavar, S GBotulinum toxin chemodenervation has evolved greatly over the past 30 years since its introduction in the 1970s for the management of strabismus. Among ophthalmic plastic surgeons, botulinum toxins are often used as the first line treatment for facial dystonias. These toxins are also efficacious for the temporary management of various other conditions including keratopathies (through so called chemo-tarsorraphy), upper eyelid retraction, orbicularis overaction-induced lower eyelid entropion, gustatory epiphora, Frey's syndrome, and dynamic facial rhytids such as lateral canthal wrinkles (crow's feet), glabellar creases and horizontal forehead lines. This article describes the pharmacology, reconstitution techniques and common current applications of botulinum toxins in ophthalmic plastic surgery.Item Carcinoma of the oesophagus: correlation of radiological appearance with response to radiotherapy.(1993-07-01) Vyas, R K; Baboo, H A; Neema, J P; Singhal, S; Dixit, S; Murthy, RIn order to predict possibility of local control in carcinoma of the oesophagus by radiotherapy, the relationship between the x-ray findings before and after radiotherapy were analyzed in 55 irradiated cases. In the superficial or proliferative type on x-ray before treatment, local control was observed in 87% cases with dose of 40 Gy, whereas in the ulcerative or infiltrative type it was observed in 20% cases. Radiation response is remarkably good in proliferative and superficial lesions seen in oesophagogram.Item Concurrent mycetoma and chromomycosis.(2011-10) Murthy, R; Swain, J PChromoblastomycosis and Madura foot are chronic localised mycotic infection of the skin and subcutaneous tissue that follows the implantation of the fungi through minor trauma, mainly found in persons working outdoors on bare foot. In cases where both Madura and chromoblastomycosis are present, the treatment becomes difficult with low cure rates and frequent relapses. Here, we present such a very rare case of a 38-year-old cattle farmer who presented with verrucose nodules, tumefaction and multiple discharging nodules on the left lower 1/3 rd leg and foot since last 9 years. Direct KOH mount of the verrucose tissue showed Fonsecaea pedrosoi sclerotic muriform bodies and a biopsy of one granule discharging nodule demonstrated fungal mycetoma. He was put on tab. Itraconazole 200 mg o.d. and cotrimoxazole bid for 6 months with very little improvement. The rarity of this combination is most probably due to different geographical distribution.Item Energy expenditure and requirement in agricultural labourers.(1966-10-01) Murthy, R; Belavady, BItem Incidence of meningitis in Manipal.(1999-04-13) Seetha, K S; Murthy, R; Shivananda, P GOne thousand one hundred and seventy cerebro spinal fluid (CSF) samples from clinically diagnosed meningitis patients were subjected to macroscopic and microscopic examination. CSF samples were also cultured. Five percent CSF samples were positive for bacterial (4.3%) and fungal (0.7%) organisms. Gram positivity was observed in 6.4% samples. The percentage of bacterial isolates was highest in newborn and infants (6.1%) and (4.3%) in patients of 1-12 years age group. Cryptococcus species were isolated from 8 adult patients. Among Gram positive bacterial isolates, coagulase negative Staphylococci was highest (8%), followed by Pneumococci (6%) and B-haemolytic Streptococci (2%). Among Gram negative bacilli, Pseudomonas aeruginosa was predominant (42%) followed by Klebsiella species (20%) though Klebsiella was predominant in newborns and infants.Item Incidence of post operative wound infection and their antibiogram in a teaching and referral hospital.(1998-12-18) Murthy, R; Sengupta, S; Maya, N; Shivananda, P GA total of 406 post-operative clean wounds were studied for the presence of sepsis and antibiogram of organisms were established. The over all post-operative sepsis rate was 13% (clinical) and 12% (bacteriological). Staphylococcus aureus (32%) and Pseudomonas species (21%) were the commonest organisms recovered and Netilmycin, Cephaloridine and Norfloxacin were the most effective antibiotics against both Gram positive and negative infections. This study reflects the change in pattern of infecting bacterial flora in case of post operative wound infections and its antibiogram.Item Leiomyosarcoma of the ovary.(1993-07-01) Dixit, S; Singhal, S; Baboo, H A; Vyas, R K; Neema, J P; Murthy, R; Sooryanaraya, UA diagnosis of leiomyosarcoma of ovary was made in a 60 year old female presenting with generalised weakness and abdominal lump. On clinical examination, a hard, big mass with some cystic areas was found occupying the pelvic cavity. Chest X-ray revealed presence of metastases. Deranged renal function and structure due to extrinsic pressure were evident on pyelography and USG. USG also suggested the ovarian origin of the mass. Fine needle aspiration biopsy was suggestive of leiomyosarcoma. Laparotomy was carried out for excision of tumor along with bilateral salpingo-oophorectomy and hysterectomy. Post-operatively renal functions normalized. A course of radiotherapy was given. At 6 months' follow-up, abdomino-pelvic sonography was normal but lung metastases were found to be enlarged. The patient was asked to follow up for chemotherapy but did not come. She died 18 months after treatment, as revealed through correspondence.Item Magnetic ocular prosthesis for shallow contracted socket(All India Ophthalmological Society, 2018-09) Murthy, R; Umesh, MContracted sockets with poor retention of ocular prosthesis are difficult to manage especially when it is a dry socket. A 50-year-old lady with history of irradiation to the socket following enucleation for retinoblastoma reported to us with severe socket contracture, dry socket, and inadequate lid closure with a poorly retained ocular prosthesis. She was using a stone in the socket for support with a cracked stock ocular prosthesis placed over it. A two-piece ocular prosthesis was created with a base and shell with neodymium-boron-ferrous magnets in each part, with good retention and positioning, and this was cosmetically acceptable to the patient. To the best of our knowledge, this is the first report of such a two-piece magnetic ocular prosthesis.