Browsing by Author "Mohamed, R"

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    Alizarin Red-S Protocol for Skeletal Staining during Fetal Period in Rabbit
    (Society for Health Care & Research Development, 2018) Mohamed, R
    Background: The main purpose of this study was to give detailed information on the staining protocol of Alizarin Red-S to detect the normal and abnormal skeleton of rabbit fetus. Methods: Eleven (9 females and 2 males) of adult rabbit weighing 3-3.5 kg were used. The female rabbits were left with buck to become pregnant then were classified into a treatment and a control group. The former group received oral doses of 400mg/kg of sodium valproate for 15 days starting from the 6th day after mating until 20th day of pregnancy, while the second received water in the same period. The pregnant rabbit was slaughtered at the 29th day of pregnancy. The live rabbit fetuses were collected. The staining protocol included fixation, dehydration, clearing, staining and preservation. The fetuses were examined under dissecting microscope and photos were taken for documentation. Results: The staining protocol made the rabbit fetuses to be clear enough to see their skeleton through the surrounding tissue. The axial skeleton including skull with mandible, vertebral column, ribs and sternum and the appendicular skeleton including the bones of the fore-and hindlimbs took the stain and became red in color. The macroscopic skeletal disorders of the fetuses of the treatment group were observed. The ossification centres were assessed. Conclusion: This protocol which depended on fixation by 95% ethanol, clearing by 1% potassium hydroxide and staining by 0.001 % Alizarin Red-S was effective in detecting normal and abnormal fetal skeletal morphology
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    Diagnostic positron emission tomography-computed tomography in clinically elusive giant cell arteritis
    (All India Ophthalmological Society, 2018-05) Mohamed, R; Djama, D; Ayoub, T
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    Gross Anatomical Study onthe Skull and Mandible ofthe Wild Boar (SusScrofa) In the Caribbean
    (Society for Health Care & Research Development, 2019) Mohamed, R
    Introduction:Wild pigs (Susscrofa), which are found throughout the Caribbean island of Trinidad and Tobago, are sometimes used experimentally, in the field of biomedical science, to model the human anatomy. In particular, the skull, which is very important as ithouses vital organs and foramina,has clinical importance in applying regional anesthesia.Subjects and Methods:The present work was conducted on two skulls and mandibles of wild pigsto grossly describe their osteology and foramina. The information garnered can be used for comparative studies of the skulls and mandibles with other similar species. The skulls and mandibles were prepared and cleaned using standard method. All of the characteristic features of various standards views of the skulls bones, including dorsal, lateral, caudal, and the lateral, rostral and caudal views of the mandibles as well as the foramina of the skulls and mandibles were described and discussed.Results:Each skull was divided into long facial and short cranial regions. The tympanic bulla was small. The supraorbital foramina and grooves were present. The zygomatic process of the zygomatic bone and the zygomatic process of the temporal bone formed the large zygomatic arch. The mandible was a paired bone with ossified mandibular symphysis. The dental formula was confirmed and it was 44 teeth.Conclusion:The bones and foramina of the skull and mandible were homologue to that of other mammals
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    Intense pulsed light versus pulsed dye laser in the treatment of nail psoriasis: Intra-patient left to right comparative controlled study
    (Scientific Scholar on behalf of Indian Association of Dermatologists, Venereologists & Leprologists, 2024-12) El Morsy, E; Mohamed, R; Omar, SI.
    Background: Until now, the management of psoriatic nails has not been satisfactory. Pulsed dye laser (PDL) as well as intense pulsed light (IPL) have been evaluated separately for the management of psoriatic nails and proved to be effective. Aim: This study aimed to measure and compare the usefulness as well as the safety of intense pulsed light versus pulsed dye laser for the management of psoriatic nails. Methods: The psoriatic fingernails of 20 patients were managed using intense pulsed light on one hand and pulsed dye laser on the other. Two to three psoriatic nails were left without treatment as controls. The therapeutic sessions were conducted monthly for a period of 6 months. Evaluation of the clinical outcomes was assessed by a blinded dermatologist depending on the total, nail bed, nail matrix, modified and target NAPSI scores. Patient global assessment, in addition to Nail Psoriasis Quality of Life (NPQL10), was performed to assess the response to the therapy. Results: A significant reduction in the total, target and modified NAPSI scores from baseline to the end of the study was detected, but no significant differences were detected between the two treatments. The responses of the nail matrix and bed lesions to both modalities were nearly the same. All patients stated that the two devices were efficient and improved their quality of life. The intense pulsed light treatment was more painful. Complete clearance of nail lesions was not obtained. Limitations: Lack of long-term follow-up of cases and preset laser parameters were the major limitations of this study. Conclusion: Intense pulsed light, like pulsed dye laser, is safe and efficient in treating nail psoriasis; however, the former is more painful. Dermoscopy had an additive function in analysing the response of nail psoriasis to therapy.