Browsing by Author "Mishra, Pinki"

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    Association of Metformin with Mortality in COVID-19 Patients: A Systematic Review and Meta-Analysis
    (Thieme Medical and Scientific Publishers Pvt. Ltd, 2023-01) Parveen, Rizwana; Mishra, Pinki; Luthra, Reva; Bajpai, Ram; Agarwal, Nidhi
    Studies have demonstrated high prevalence of mortality in coronavirus disease (COVID-19) patients with type 2 diabetes mellitus; however, the effects of antidiabetic pharmacotherapy on COVID-19 complications need further exploration. The aim of the study was to explore the association of metformin use and mortality in COVID-19 patients. A literature search was conducted using the databases Medline (via PubMed) and Cochrane Central Register of Controlled Trials until February 09, 2021. Nine studies were included in the meta-analysis, including 12,684 COVID-19 patients. The meta-analysis suggested 37% lower risk of mortality in patients receiving metformin (risk ratio: 0.63; 95% confidence interval: 0.50–0.78; p?