Browsing by Author "Menezes, S"
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Item Auto immune haemolytic anaemia.(1981-08-01) Parashar, S; Bhandary, S; Menezes, S; Kamat, L; Hede, S S; Fernandes, H; Bangotra, A KItem Bernard Soulier's syndrome.(1980-11-01) Menezes, S; Parashar, S KItem Cell surface alterations induced by methylene blue and direct electric current in Escherichia coli.(1998-10-20) Holandino, C; Capella, M A; Angluster, J; Silva-Filho, F C; Menezes, S; Alviano, C SCell surface properties, including hydrophobicity, zeta potential, carbohydrate and fatty acid components, were altered on treatment of E. coli K12 with methylene blue (MB) and direct electric current (DC). The treatment of fimbriated E. coli cells with MB greatly increased the agglutination of yeast cells when compared to untreated bacteria. However, this increased agglutination was markedly reduced when the bacteria were treated with MB plus DC. These results suggest that MB modifies cell surface components in the absence of light and these alterations are more pronounced when cells are treated simultaneously with MB and DC.Item Damage induction by direct electric current in tumoural target cells.(2000-06-16) Holandino, C; Veiga, V F; Capella, M M; Menezes, S; Alviano, C SDamage induction to tumour target cells (P815) by direct electric current (DC) was investigated. A 6 min treatment of P815 cells with DC generated decreased levels of cell viability and proliferation. The ultrastructural analysis of DC-treated cells revealed the presence of blebs, loss of cell surface filopodia, and ruptures in cell membrane. Mitochondrial alterations, swelling of cells, cytoplasmic matrix rarefaction, and cellular debri formation were also observed. The study shows that tumoural target cells can be damaged by direct electric current and this approach may provide means to understand the mechanism of tumour regression induced by electrochemical therapy.Item Sister Mary Joseph's nodule--diagnosis of umbilical metastases by fine needle aspiration.(1995-01-01) Mallya, M V; Mandrekar, S; Nadkarni, N S; Menezes, SA 40 year old male patient presented with jaundice. The patient had a small periumbilical nodule. He was referred to the department of Pathology for FNAC of the nodule. A diagnosis of metastases from adenocarcinoma was made. Further investigations revealed carcinoma of stomach with metastatic deposits in liver. The present report highlights the utility of F N A C in diagnosis and to decide on further investigations to arrive at a final diagnosis in a given case. A brief review of historical aspect is also given.Item A study of leukaemia in Goa.(1977-04-01) Menezes, S; Malik, G B