Browsing by Author "M, S."
Now showing 1 - 6 of 6
Results Per Page
Sort Options
Item Aging effect on cardiac sympathovagal activity in healthy males over seven decades using short-term heart rate variability analysis(Mrs Dipika Charan of MedScience (India) Publications, 2022-02) S, SJ; M, S.Background: The autonomic nervous system (ANS), which governs practically all bodily processes, alters structurally and functionally as we age. Heart rate variability (HRV) studies are non-invasive, quantitative approaches to investigate the effects of ANS activity on the heart and also a marker to predict mortality. Aim and Objectives: This study was undertaken to assess the effect of aging on cardiac sympathovagal activity in healthy males over seven decades using short-term HRV analysis. Materials and Methods: This cross-sectional study was conducted on healthy in the age group of 10–69 years. Participants were divided into many age groups based on their decade of birth. Short-term HRV recording was done. In frequency domain analysis, spectral estimates of RR intervals was done by integrating the power as total power, low-frequency power (LF), high-frequency power (HF). In time-domain analysis, SDNN, RMSSD, and pNN50% were studied. Data were subjected to statistical analysis using ANOVA. Results: In the frequency domain analysis of HRV, all the components such as total power, HF in nu and msec2, LF in nu and msec2, LF/HF ratio decreased as the age advances. In the time domain analysis of HRV, all the components decrease as age advances. When the values were compared with other age ranges, a significant decrease with aging only with respect to the comparisons between the youngest (10–29 years) and oldest (50–69 years) groups. Conclusion: Our study found a global decrease in all the HRV indices. The decline in time domain indices was rapid in the early ages, stabilized out at the age of 40, and then declined gradually.Item Assessment of physical activity and physical fitness among undergraduate medical students(Mrs Dipika Charan of MedScience (India) Publications, 2023-01) Polina, SV; K, JA; Priyadharshini, KU; S, S; B, P; M, S.Background: In a nationwide survey conducted in the Indian Council of Medical Research- INdia DIABetes study (Phase-1) 2014 on physical activity and inactivity patterns, overall, 392 million individuals in India are physically inactive. Physically active medical students tend to recommend physical activity for patients or at-risk individuals in their future practice. Exercise is a subset of physical activity that is planned, structured, and repetitive which helps in achieving physical fitness. Aim and Objectives: The aim of the study was to assess the prevalence of physical activity (PA) and physical fitness among medical students and to correlate both. Materials and Methods: This is a cross-sectional study, in which physical activity level was assessed using Global Physical Activity Questionnaire. Physical fitness using Harvard step test, hand grip dynamometer, sit-up and push-up test, shoulder – flexibility test, body mass index, and body adiposity index was assessed among 150 medical students in a tertiary care hospital. Results: Physical activity level when analyzed, 16% of students performed low PA, 74% belonged to moderate PA Group, and 10% in high PA group. When mean metabolic equivalent of task min/week attained by study population in three domains of physical activity (work/travel/recreation) was analyzed, results showed no significant difference between males and females in different domains of physical activity. Conclusion: Although the students met the recommended physical activity as per the World Health Organization, physical fitness was not achieved up to the desired level. No correlation was noted between physical activity and physical fitness among medical students.Item Assessment of the quality of randomized controlled trials published in Indian Medical Journals from 2020 to 2021: A cross-sectional study(Mrs Dipika Charan of MedScience (India) Publications, 2022-12) D, A; M, S.Background: A randomized controlled trial (RCT) is the most valued method for evaluating the drug safety and its efficacy. However, due to incomplete reporting, RCTs may not be a reliable source of information and can lead to false interpretation of outcome. Aim and Objective: The aim of this study was to analyze the completeness in reporting of RCTs published in the Indian medical journals (IMJs) according to the Consolidated Standards of Reporting Trials (CONSORT) 2010 checklist items and to analyze, if there was a variation in the completeness between registered and unregistered trials. Materials and Methods: This was a cross-sectional study conducted in the Department of Pharmacology, Bangalore Medical College and Research Institute. The clinical trials published by the IMJs between January 2020 and August 2021 were accessed online, and its full text versions published were downloaded. Completeness in reporting of the RCTs with respect to different CONSORT checklist domains was recorded. The impact of trial registration and CONSORT endorsement on the completeness of reporting RCTs according to CONSORT checklist was determined. Descriptive statistics was used to assess and summarize the data. Results: The overall completeness of reporting was 82.4%, better than the previous years. Major areas of reporting deficiencies were in the title and abstract, result, and registration domains. Registered trials reported better than unregistered. Conclusions: Endorsement of CONSORT in the journal had no difference in reporting. Although the quality of reporting RCTs in the IMJs has improved, it remains unsatisfactory. Completeness of trial reporting could be improvised by strict implementation of CONSORT guidelines.Item Bilateral electrodermal activity and asymmetric responses in normal healthy individuals(Mrs Dipika Charan of MedScience (India) Publications, 2023-01) LK, S; M, S.Background: Electrodermal activity (EDA) or galvanic skin response (GSR) is the change in the electrical properties of the skin which is used to measure the sympathetic activity and response. When a painful stimulus is applied, it elicits a sympathetic response by increasing sweat gland activity that, in turn, increases the skin conductance. Central nervous system plays important role in regulating sympathetic activity. Aims and Objectives: The objectives of this study were as follows: (1) To evaluate the electrodermal responses (EDR) in dominant and non-dominant hand; (2) to compare the EDRs in dominant and non-dominant hand. Materials and Methods: The study was done among MBBS students of age 18–23 years in physiology research laboratory and EDA values were analyzed using BIOCHART software (version1.0) through physiograph. EDA was recorded using skin surface electrodes. Pulse and blood pressure were monitored before and after immersion in cold water. Baseline recording, recording after immersion of hand in cold water, and recovery recording of GSR were noted in dominant and non-dominant hands. Results: The mean GSR, baseline value, and the GSR after cold stimulation were significantly more in non-dominant hand compared to dominant hand. Conclusion: Our findings show an increased sympathetic activity in non-dominant hand in response to cold stimulation compared to dominant hand.Item A drug utilization study in post-operative patients of obstetrics and gynecology of a tertiary care teaching hospital(Mrs Dipika Charan of MedScience (India) Publications, 2022-10) S, A; M, S.Background: After any kind of surgery, many drugs are prescribed for prevention of infection, analgesic purpose, nausea, vomiting, gastritis and to maintain the hemodynamic status. Drug utilization studies are conducted for a variety of reasons, including consumption, off-label use, medication errors, misuse, and treatment dynamics. It is done to identify the problems associated and help the prescribers to optimize resource allocation and utilization. Aim and Objectives: This study was conducted with the objective to reconnoiter the utilization pattern of various medications in obstetrics and gynecological post-operative cases for assessment of various medications prescribed, their route of administration, their duration of use, and the World Health Organization (WHO) core drug indicators. Materials and Methods: This was a Prospective Observational study conducted after obtaining approval from the Institutional Ethics Committee. Data were collected from patients case sheets during the period of April 2019 to June 2019, in the post-operative wards of obstetrics and gynecology department using a structured pro forma. Results: A total of 100 patients were prescribed with different medications such as antimicrobials, analgesics antacids, with an average of 7.48 drugs per encounter. Injectable drug encounters was up to 92 %. Antimicrobials were prescribed upto 88 %) and the most common being metronidazole which was prescribed to 80% of patients. The most common analgesic prescribed was diclofenac for 73% of patients. Out of 41 different types of drugs prescribed, 45 (45%) were prescribed by their generic name and 91 (91%) were from the Essential Medicines WHO Model List (2021). Conclusions: The present study provides a valuable insight about the overall pattern of drugs prescribed in postoperative patients in the obstetrics and gynecology unit of a tertiary care hospital. Though only one half of the medications prescribed were by the generic name, a very good proportion of medications were prescribed from the Essential Medicine List. This report is mainly intended to be a step in the wider assessment of safety and efficacy of drugs prescribed in post-operative wards.Item Knowledge, intention, and practice of wearing face mask by common people to ensure protection against COVID-19 during pandemic(Mrs Dipika Charan of MedScience (India) Publications, 2023-05) Meher, SK; Meher, P; Nanda, RK; M, S.Background: Since the outbreak of global pandemic, wearing face mask not only protects the individual but also limits the spread of corona virus infection in the community. However, certain sociocultural and personal factors have created hinderance in wearing face mask by general people against COVID-19 virus. Aims and Objectives: The aim and objective of this study is to assess the knowledge, intension, and practice of wearing face mask among common people. Materials and Methods: It was a cross-sectional study conducted among general people in a part of Western Odisha after ethical approval. A total of 1050 adults above 18 years participated in this study. The data were collected from different locality of the town using a pretested self-administered questionnaire by all authors and research assistants of this project. The period of study was from July 2021 to December 2021. The results were tabulated, processed, and analyzed using SPSS-20. Results: Regarding knowledge score, we observed that 57% had average, 18% had poor, and 25% had good knowledge. Furthermore, we found 42% participants had positive intention and 58% had negative intention. Again we assessed that 35% of participants were practicing face mask appropriately and 65% practicing inappropriately. Conclusion: In this study, the score of knowledge, intention, and also the practice of wearing face mask against COVID-19 was lower than the average as compared to previous researches. Hence, health authorities should promote the people to wear mask and encourage awareness programs for the benefit of the society.