Browsing by Author "Lakshminarayana, P"

Now showing 1 - 13 of 13
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    Anthropometry for syndromology.
    (1991-03-01) Lakshminarayana, P; Janardhan, K; David, H S
    In diagnosing certain syndromes, abnormal facial features such as hypertelorism, low set ears or wide nasolabial distance are taken into consideration. Most often the description is from a visual impression, which may prove wrong as it is only relative. Detailed studies have, so far been only from the west, except for two, from northern India. These values may not suit us as facial features and measurements vary in different populations. This study was undertaken to set up a standard for the south Indian population, to detect deviations and to compare our figures with those from other studies. Measurements were taken in 850 children, from birth to 11 years of age (horizontal study). The parameters studied were the inner and outer canthal distances, from which interpupillary distance was calculated; nasolabial distance, ear length, ear set, hand length and AF/AT ratio. The average measurements for various features (50th percentile) 3rd and 97th centile are presented in tables. Besides providing standards, this paper will aquaint the pediatricians on the need to actually measure the features rather than rely on ones impression on physical features in diagnosing syndromes.
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    Body stalk anomaly.
    (1993-05-01) Lakshminarayana, P; Lakshmi, P S; Radhika, J
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    Ethmocephaly, encephalocele and proboscis.
    (1995-12-01) Lakshminarayana, P; Radhika, J; Srilakshmi,
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    Foetal growth as assessed by anthropometric measurements.
    (1974-12-01) Lakshminarayana, P; Nagasamy, S; Raju, V B
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    Genetic disorders: practitioner's approach.
    (1994-07-01) Lakshminarayana, P; Vidyashankar, C
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    Influence of nutrition on delayed skin hypersensitivity.
    (1979-01-01) Narain, R; Lakshminarayana, P; Vallishayee, R S; Narmada, R; Diwakara, A M
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    Inherited 11q partial trisomy.
    (1995-03-01) Lakshminarayana, P; Suresh, S; Suresh, I; Sriram, U; Jabeen, G
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    KAP study on mothers of children with Down syndrome.
    (1991-09-01) Lakshminarayana, P; Ibrahim, S; Venkataraman, P; Jagatheesan, T; Kamala, K G
    We evaluated 50 mothers of children with Down syndrome attending Genetic Clinic of the Institute of Child Health and Hospital for Children, Madras, with special reference to their knowledge, belief and attitudes in the care of these children. After evaluation, they were educated individually and in groups with demonstration, picture cards and pamphlets, on the causation, expected health problems, developmental potential of Down syndrome and the ways and means to help the child to attain the maximum developmental potential. They were taught on preventive aspects of Down syndrome as well. Re-evaluation was done after three months, and considerable improvement was noted in the mother's knowledge, and attitude towards bringing up such a child. The mothers also showed an improvement in the skills in providing developmental enrichment to these children. Thus this study has formulated a programme in the management of such children, which can be practised on any population, anywhere, especially, in rural areas, and by less affluent folk, with poor educational background.
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    Lateralised sympodia.
    (1993-09-01) Prakash, S; Radhika, J; Paul, S; Lakshminarayana, P
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    Lethal multiple pterygium syndrome.
    (1992-10-01) Lakshminarayana, P; Jegatheesan, T; Venkataraman, P
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    Partial trisomy of chromosome 10 inherited from a carrier father.
    (1995-09-01) Suresh, S; Suresh, I; Lakshminarayana, P; Jabeen, G; Rajesh, K
    Partial trisomy of chromosome 10q is a very rare condition with only four cases having been reported int he literature. This report describes a neonate with symmetric growth retardation and multiple dysmorphic features, in whom G-banded chromosomal analysis revealed a partial trisomy of chromosome 10q (q2.4-q ter). The father was diagnosed as a carrier of a balanced translocation with a karyotype of 46, XY t(10.3) (q2.4L : pter). In patients with a bad obstetric history, genetic counselling prior to a new conception cna aid in early prenatal diagnosis of fetuses with recurrent chromosomal abnormalities by means of fetal tissue sampling.
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    Spondylocostal dysplasia.
    (1992-07-01) Lakshminarayana, P; Janardhan, K; Jegatheesan, T; Prakash, S
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    Translocation Down's syndrome.
    (1990-03-01) Lakshminarayana, P
    Among the 500 Down syndrome children karyotyped, 15 (3%) were due to translocation; 10 were 21;21 translocation and five 14;21. There were 9 cases of de novo translocations, while 6 were inherited from father or mother. Family history was characteristic in all the translocation cases, with younger parental age, fetal wastage in the family, recurrence and with the affected child often being either the first or the only liveborn in the family. The pattern of translocation in Madras and the significance of family history in genetic counselling are discussed.