Browsing by Author "Lakshmi, Vijaya"

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    Effect of thyroxine therapy on autonomic status in hypothyroid patients.
    (2009-07) Lakshmi, Vijaya; Vaney, N; Madhu, S V
    The aim of the present study was to evaluate the impact of hypothyroidism on the autonomic regulation of the cardiovascular system by analyzing sympathetic and parasympathetic influences on the heart and the effect of thyroxine replacement. Thirty newly diagnosed female hypothyroid patients with mean age 32.73±9.98 years were recruited from the Thyroid Clinic, GTB Hospital, Delhi. Various Autonomic function tests to assess Basal heart rate variability, parasympathetic activity (E:I Ratio, 30:15 Ratio, Valsalva Ratio) and sympathetic activity (Postural Challenge test, Sustained handgrip test) were done before and after attainment of euthyroidism. There was significant increase in parasympathetic activity on achieving euthyroid state. The sympathetic activity too significantly improved after L-thyroxine supplementation. Lipid profile parameters significantly decreased after achieving euthyroid state. Our findings are consistent with previous reports that thyroxine therapy appears to restore the efferent vagal activity and alters the relative contribution of systems that maintain resting blood pressure and heart rate.
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    Microperforated hymen with pregnancy presenting at term: an accidental diagnosis
    (Medip Academy, 2023-12) Bulusu, Ratna; Reddy, Swati A.; Lakshmi, Vijaya
    Anatomic variations of the patent hymen exist, the most common configuration having a central orifice. Difficulty in inserting a tampon or the inability to achieve vaginal intercourse in an adolescent is the typical presenting symptom of incomplete hymenal obstruction. Here, a case is reported wherein the patient presented with normal pregnancy at term with an apparently intact hymen. Later in labour, a microperforate hymen (MH) was noted. An emergency lower segment caesarean section along with hymenectomy was performed.