Browsing by Author "Kumari, K. Swarajya"

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    Histopathological Spectrum Of Enucleation Specimens In A Tertiary Care Hospital - A 3 Year Study
    (Indian Society for Health and Advanced Research, 2024-06) Kakumanu, Richards; Prabu, Varsha; Y., Harsha Vardhan; Kumari, K. Swarajya
    Enucleation, or surgical removal of the entire eye globe is performed for many end stage eye disease. Eyeball lesions comprise a wide spectrum of disease and the pattern and frequency of these lesions differ in various geographical regions. Our aim was to study the spectrum of eyeball lesions and to determine the distribution of patient age, gender, location and histological type. A retrospective study was conducted at the Department of Pathology, Sarojini Devi Eye Hospital, Hyderabad, Telangana for a period of 3 years. All the enucleation cases were selected and reviewed. The data collected were entered into Microsoft Excel worksheet and statistical tabulations were done. A total of 60 enucleation cases were reviewed. Out of them, 20 cases (33.3%) were Retinoblastoma, 15 cases (25%) were Phthisis Bulbi, 6 cases (10%) were of Squamous Cell Carcinoma and Trauma each, 4 cases (6.7%) of Invasive Fungal Infection, 3 cases (5%) were of Choroidal Melanoma and Panophthalmitis each. Most common age group that underwent enucleation in our study was 0-10 years. Overall lesions were more common in males 38 cases (63%) as compared to females 22 (37%) and Right Eye enucleations were 1.3 times more frequent (34 cases). Some rare causes of enucleation included Malignant Melanoma, Sebaceous Carcinoma and Craniosynostosis with herniation of brain into orbital apex. The most common causes of enucleation in our study were intraocular malignancy, painful blind eye and traumatic injury. Increased frequency in the young children was due to Retinoblastoma. Prompt diagnosis of intraocular malignant tumors (retinoblastoma and squamous cell carcinoma) may reduce the need for enucleation.
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    Seroprevalence Of Hepatitis B In Healthy Blood Donors At Blood Bank Of Osmania General Hospital
    (World Wide Journals, 2018-07) Kumari, K. Swarajya; Shaik, Mamula
    Background - With every unit of blood, there is 1% chance of transfusion - associated problems including transfusion - transmitted disease. Hepatitis B infection is one of the transfusion transmissible infections, hence it is mandatory to test all blood donors for HBsAg and other infections like HIV, HCV, syphilis and malaria. Serosurveys are one of the primary methods to determine the prevalence of HBsAg. Objective - The aim of the present study was to know the seroprevalence of hepatitis B among blood donors and to compare the prevalence with other areas in India. Materials and methods - The retrospective study was conducted at the blood bank of Osmania general hospital. In this study blood donation records were reviewed over a period of two years from July 2012 to June 2014. Results - In the present study 6267 donors were reviewed, majority of them were 5948 (95%) males and 319 (5%) females. Majority of the donors belonged to the age group of 18-40 yrs. Seropositivity of HBsAg was higher among other transfusion transmitted diseases. Conclusion - The most complete data providing a picture of hepatitis B disease burden in India come from HBsAg seroprevalence studies. Decreasing trends of seroprevalence of HBsAg can be achieved by Increasing the public awareness about the disease and modes of prevention.