Browsing by Author "Kumar, M"
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Item Absence of hyperlipidaemia in patients of chronic renal failure in Chandigarh.(1980-09-01) Sharma, B K; Jindal, S K; Rana, D S; Gupta, B; Kumar, MItem Acute idiopathic gastric gangrene with perforation.(2010-10) Tiwari, N; Sharma, A K; Galagali, A; Kumar, M; Chand, KItem Adeno-acanthoma of gall bladder.(1980-02-01) Kumar, M; Prasad, MItem AIDS associated cholangiopathy.(1998-10-06) Kumar, M; Murthy, A; Duggal, L; Sud, RItem Anhidrotic Ectodermal Dysplasia (Christ-Seimens-Touraine syndrome)--case report with a review.(2000-12-17) Ali, G; Kumar, M; Verma, R; Khajuria, V; Wadhwa, M BAnhidrotic ectodermal dysplasia commonly transmitted as an x-linked recessive disorder is very rare. The complete syndrome occurs in males and females are carriers. Our patients comprised two sisters who had the complete syndrome. This is much rarer and is reported to be inherited as autosomal recessive disorder, there are only a few case reports of females presenting with a complete syndrome in the literature.Item Arcane Language of Human Emotions: Envy and Jealousy in Academia(Medsci Publications, 2022-09) Kumar, M; Kumari, A; Sharma, K.Jealousy and Envy are essential part of human emotions and behavior. In today’s fast-moving world where everyone is in rush to cut-throat competition, it is more important to discuss these emotions than ever before. Jealousy and envy somewhere connected. Jealousy is a practice to defend something that is owned and threatened whereas envy is a tendency to obtain something that does not own by one. Jeal-ousy and envy develop naturally and also test their character by the response they give due to emotional burnout. Sometimes these situations broke and turn healthy competition into a rivalry at cost of long-standing personal relationships. Jealousy and envy include compound emotional experiences during the exercises to acquire or not lose something desirable. The impact of envy and jealousy is not assessed in academia and research area moreover it is important to understand that envy is often hidden in the classroom context, but it must still be discussed.Item Arrhythmias in inferior wall infarction.(1983-09-01) Ananthasubramaniam, G; Kumar, M; Chenniappan, M; Surana, G C; Ambika, AItem An Assessment of Skin Diseases in People and Their Quality of Life in Bundelkhand Region of Uttar Pradesh(MRI Publication Pvt. Ltd., 2023-06) Kumar, M; Singh, S; Barman, S; Singh, LD; Kumar, N; Barman, SK.Background: Skin diseases occur in all age groups in developed and developing countries. Various types of skin diseases are found worldwide and depend on factors like environment, surrounding ecology, dietary habits, socioeconomic status, mental health, and literacy. Health-related quality of life (HRQOL) improves after treatment or cure of the diseases. Objectives: To estimate the pattern of skin disease. To find out the quality of life and association of skin disease with sociodemographic factors among patients. Methods: This observational cross-sectional study was done in skin OPD at the tertiary care center, Banda district of Uttar Pradesh, India from May 2022 to July 2022. All patients who attended to skin OPD during study period were included in the study after taking informed verbal consent. Results: Skin diseases had further divided in subcategories which were infectious conditions, pigmentary disorders, inflammatory dermatoses, miscellaneous skin conditions, benign tumor and other lesions with their percentage 44.8, 10.5, 28.6, 7.1, 2.9 and 6.2%, respectively in this study Classes of DQLI where major portion of patients (49.52%) were in ‘Small effect on patient’s life’ category. The relation of age, religion, education and member of household with history of skin disease were found to be highly statistically significant. Conclusion: Infectious skin diseases were found more common in study area. Male populations were more commonly affected. Skin diseases were more common in age group of 18–60 years. Study participants showed no predominant effect on quality of life. But small effect class had major effect on participant’s quality of life.Item Association Of the Methylene Tetrahydrofolate Reductase (MTHFR) Gene Polymorphism with Susceptibility to Recurrence of Cardiovascular Outcomes Among Ischemic Stroke- A Randomized Controlled Trial(Medsci Publications, 2022-10) Kataria, N; Kalyani, VC; Mirza, AA; S, V; Kumar, M; Bharupi, Y; Ranjan, S; Kumar, N; Kumar, NBackground: Hyperhomocystenemia and genetic variants are factors for causing young age stroke glob-ally. This study aims to identify homocysteine related-MTHFR gene polymorphism that associated with recurrent cardiovascular outcomes. Methodology: A randomized controlled trial conducted upon 90 hyperhomocysteinemic ischemic stroke patients were taken from the neurology wards of a tertiary care hospital were randomly selected into vitamin B therapy group and control groups (n=45 in each group). Baseline subject details were col-lected venous blood sample for MTHFR genetic testing via PCR-RFLP technique along with blood homo-cysteine levels, vitamin B12, folic acid levels. Results: The results showed that the frequency of CT genotype polymorphism was 15.5% vs 13.3% for the MTHFR C677T gene without any significant difference between vitamin group and control group re-spectively (p-value >0.05). The reduction in mean homocysteine up to -6.77±4.50 versus -2.08±0.71 μmol/L in the vitamin group as compared to control group respectively, p value 0.001. Conclusion: Considerable amount of MTHFR gene polymorphism found among hyperhomocysteinemic ischemic stroke of sub-Himalayan region. Nutritional deficiencies including vitamin B 12 & folic acid, and some hidden reasons found, which could lead to the primary cause of hyperhomocysteinemia. Vitamin B therapy is an effective for reducing homocysteine.Item Benign recurrent intrahepatic cholestasis.(2005-09-28) Gupta, V; Kumar, M; Bhatia, Baldev DBenign recurrent intrahepatic cholestasis (BRIC) is a rare cause of cholestasis in children. The disease may start in infancy or early childhood. Jaundice persists or recurs throughout life but does not lead to chronic liver disease or cirrhosis. Treatment is mostly symptomatic. The condition has not been reported in Indian children. We report an interesting case of BRIC in a 9-year-old boy who had recurrent episodes of jaundice since when he was 1 yr old.Item Blood sugar studies during thiopentone anaesthesia.(1964-07-01) Kumar, M; Saraf, K LItem Brachytherapy in modern oncology practice: A survey based assessment of knowledge levels among oncology professionals and need for comprehensive oncology education.(2015-10) Sujith, K M; Chakraborty, S; Geetha, M; Kumar, M; Balasubramanian, SItem Carcinoma gall bladder presenting as metastatic lung disease.(1999-01-04) Puneet,; Khanna, R; Kumar, M; Khanna, A KItem Castlemans disease: retroperitoneal tumor, lichen planus and erythema multiforme.(1998-07-08) Waghela, J; Murlidhar, V; Nandgaonkar, S; Kumar, M; Iyer, L; Jerajani, H; Dhurat, R S; Randive, N UItem Chandelier-assisted scleral buckling in an eye with longstanding inert foreign body with fresh rhegmatogenous retinal detachment(All India Ophthalmological Society, 2019-03) Kumar, M; Konana, VK; Kanakamedla, A; Kumar, D; Gudimetla, JIntraocular foreign bodies (IOFBs) present in varied manners which in turn necessitate their removal in majority of the cases. A stone foreign body can remain inert inside the eye for years. Retinal detachment in eyes following penetrating trauma with an IOFB is common, but a combination of fresh rhegmatogenous retinal detachment in an eye with a longstanding inert stone foreign body is extremely rare. We report a case of a 50-year-old male with rhegmatogenous retinal detachment with a longstanding stone foreign body, where we managed such a scenario with a chandelier-assisted, sutureless, scleral buckle without removing the stone foreign body.Item Changing patterns and trends of multidrug-resistant tuberculosis at referral centre in Northern India: A 4-year experience.(2013-01) Maurya, A K; Singh, A K; Kumar, M; Umrao, J; Kant, S; Nag, V L; Kushwaha, R A S; Dhole, T NPurpose: India has a high burden of drug-resistant tuberculosis (TB), although there is little data on multidrug-resistant tuberculosis (MDR-TB). Although MDR-TB has existed for long time in India, very few diagnostic laboratories are well-equipped to test drug sensitivity. The objectives of this study were to determine the prevalence of MDR-TB, first-line drug resistance patterns and its changing trends in northern India in the 4 years. Materials and Methods: This was a prospective study from July 2007 to December 2010. Microscopy, culture by Bactec460 and p-nitro-α-acetylamino-β-hydroxypropiophenone (NAP) test was performed to isolate and identify Mycobacterium tuberculosis (M. tb) complex (MTBC). Drug sensitivity testing (DST) was performed by 1% proportional method (Bactec460) for four drugs: Rifampicin, isoniazid, ethambutol and streptomycin. Various clinical and demographical profiles were evaluated to analyse risk factors for development of drug resistance. Results: We found the overall prevalence rate of MDR-TB to be 38.8%, increasing from 36.4% in 2007 to 40.8% in 2010. we found that the prevalence of MDR-TB in new and previously treated cases was 29.1% and 43.3% ( P < 0.05; CI 95%). The increasing trend of MDR-TB was more likely in pulmonary TB when compared with extra-pulmonary TB ( P < 0.05; CI 95%). Conclusions: we found a high prevalence (38.8%) of MDR-TB both in new cases (29.1%) and previously treated cases (43.3%).This study strongly highlights the need to make strategies for testing, surveillance, monitoring and management of such drug-resistant cases.Item Class I histiocytosis: response to combination of etoposide and prednisolone.(1999-01-10) Datta, V; Mishra, O P; Das, B K; Kumar, M; Bhargava, V; Singla, P NItem Clinical study of the role of collagen sheet cover in the management of burn wounds.(1983-04-01) Yadava, V N; Srivastava, M; Garg, R K; Kumar, MItem Clinico-epidemiological profiles of post-kala-azar dermal leishmaniasis in Varanasi.(1989-09-01) Rai, R N; Kumar, M; Srivastava, A; Joshi, R D; Asthana, A K; Tripathi, V C; Dutta, K KTwenty-seven cases of Post Kala-Azar Dermal Leishmaniasis (P. K. D. L.) were detected in an endemic focus of Kala-azar in Sujabad village in Varanasi Distt. Male-Female ratio of cases was 4.4:1. Majority (66.6 per cent) of cases had macular lesions. Histopathology of one case showed Leishmania donovani (L. D.) bodies. Densities of sand fly were more in pockets where P. K. D. L. cases were detected. All the 13 cases, which were treated with sodium antimony gluconate, responded well to therapy.Item Collagen sheet and its usefulness in healing of ulcers in leprosy patients.(1987-10-01) Rao, K S; Kumar, M; Oommen, P K; Swamy, M K; Selvaganapathy, SCollagen is a natural tissue present in the body. For healing of any part collagen is essential. Collagen has been made available in the form of sheets for clinical use, by the Central Leather Research Institute, Adyar, Madras 20. It has been tried in burns and ulcers. Plantar ulcers are common in leprosy and pose a problem in healing. Therefore, collagen was tried in our Institute on 75 patients having plantar ulcers, other type of ulcers like stasis ulcers and post operative wounds. It has been found from our study that Collagen Sheet hastens the healing of wounds.