Browsing by Author "Khan, N"

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    Acute reversible membrano-proliferative glomerulonephritis after cobra snake bite.
    (1985-08-01) Jain, A P; Gupta, K; Gupta, O P; Jajoo, U N; Khan, N
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    Caries prevalence, oral hygiene and orthodontic status of Saudi Bedouin children.
    (2001-10-04) Wyne, A; al-Dlaigan, Y; Khan, N
    The objectives of the study were to determine caries prevalence, oral hygiene and orthodontic status of Bedouin children in a desert around Al-Qasseem Region of Saudi Arabia. One hundred and fifty three children were examined for caries, oral hygiene and orthodontic status with mirror and explorer utilizing natural light. These children were divided into two groups for analyses. The primary dentition group consisted of 77 children, 39 (50.6%) male and 38 (49.4%) female with a mean age of 4.0 (+/- 1.4) years. The mixed dentition group consisted of 76 children, 67 (88.2%) male and 9 (11.8%) female with a mean age of 9.7 (+/- 2.9) years. In Primary dentition group, 16 (20.8%) children were caries positive and mean DMFT was 0.91 (+/- 2.42). There was a highly significant relation (p < .001) between oral hygiene and caries. In the mixed dentition group, 15 (19.7%) children were caries positive. The mean DMFT and DMFT scores for these children were 0.72 (+/- 1.96) and 0.74 (+/- 1.48) respectively. There was a significant relation (P > .01) between oral hygiene and caries. One hundred and fifty one (98.6%) children had class I molar relation and 2 (1.4%) children had class II molar relation. Anterior open bite, anterior crossbite and posterior crossbite were found in one case (0.7%) each. The caries experience of these Bedouin children was low both in terms of prevalence and severity. There was a significant relation between oral hygiene and caries. The orthodontic problems were almost nonexistent in the study population.
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    Clinico-pathological study of nephrotic syndrome in leprosy.
    (1983-07-01) Jain, A P; Khan, N; Gupta, O P; Gupta, G; Moghe, K V
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    Clinicopathological study of non-neoplastic lesions of nasal cavity and paranasal sinuses.
    (2008-01-18) Zafar, U; Khan, N; Afroz, N; Hasan, S A
    An analysis of cases presenting as mass in nasal cavity (NC), paranasal sinuses (PNS), and nasopharynx (NP) was done over a period of 7 years in Jawaharlal Nehru Medical College, Aligarh. A provisional diagnosis was made after clinical assessment and radiological investigations, but final diagnosis was made after histopathological examination. The incidence of masses in NC, PNS, and NP was 34.3 cases per year, non-neoplastic lesions constituted 60% of these cases and their incidence was 20.7 cases per year. All the cases were carefully examined histopathologically and it was found that the region was affected by a variety of non-neoplastic lesions. Among 240 cases, 145 were non-neoplastic and 95 were neoplastic The lesions in the decreasing order of frequency were - nasal polyp, rhinoscleroma, tuberculosis, fungal infection, fibrous dysplasia, ossifying fibroma, cysts, nasal glioma, and cemento-ossifying fibroma. NP was involved by a range of neoplastic lesions; however, no non-neoplastic lesion was seen in this region.
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    Comparative evaluation of breast lesions with the help of impression smears, histopathology and mammography.
    (1997-07-01) Trivedi, N; Khan, N; Sherwani, R; Verma, A K; Ranga, S; Talib, V H
    A total of 148 surgically removed benign and malignant breast lesions were studied to correlate cytomorphologial features in impression smears and histopathological sections. Mammograms were taken prior to surgery. Role of mammography in detection of non-palpable breast lesions was enlightened. Impression smears helped in quick diagnosis (intraoperative) and overall accuracy obtained was 97.4%. Cluster predominant and Grade II nuclear grading on smear pattern was seen in 58.8% and 57.4% cases respectively amongst the 68 malignant cases. 45% cases revealed non-palpable breast lesions on mammography which was later confirmed on histopathology.
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    Conjunctival dysplasia (a case report).
    (1984-03-01) Sane, S S; Khan, N; Ingole, N S
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    A correlative study of alpha-1-antitrypsin and hepatitis B surface antigen in conventional paraffin sections of chronic liver diseases.
    (1985-04-01) Khan, N; Gupta, S G; Ramachandran, A; Gupta, O P; Jajoo, U N; Jain, A P
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    Cranio-fascial tuberculosis.
    (1984-10-01) Bhatia, B D; Aggarwal, N K; Dubey, A P; Garg, A; Khan, N
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    Diagnostic and prognostic significance of serum cholinesterase and lactate dehydrogenase in breast cancer.
    (1991-04-01) Khan, N; Tyagi, S P; Salahuddin, A
    Serum cholinesterase (ChE) and Lactate dehydrogenase (LDH) activities were estimated in 40 cases of carcinoma breast, 25 cases of benign tumours and compared with healthy controls (30 cases). Significant difference in enzyme activities were obtained between benign and malignant neoplasms of the breast when compared with each other as well as when compared with healthy controls. Also, there were significant enzyme changes between non-metastatic cases and those with metastasis and when Stage I and Stage II cancers were compared with those in Stage III and Stage IV. No difference in enzyme levels were recorded between pre and post-operative cases and in different types of breast cancers. While ChE was depressed in 80 per cent cases of malignancy breast, serum LDH was raised in 73.3 per cent cases.
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    Evaluation of breast mass and applicability of histopathology and sonomamography for accurate diagnosis of malignant masses
    (Educational Society for Excellence, 2016) Khan, N; Khan, S.
    Breast or mammary gland is a modified sweat gland. The mammary gland is a superficial organ. Breast carcinoma is the most common cancer in women all over India and accounts for 25% to 31% of all cancers in women in Indian cities. With the increased incidence of breast cancers every breast lump needs to be evaluated so as to assure the patient of its nature. The study was based on 50 patients who were referred to the Department of Radiodiagnosis and Imaging for evaluation of breast lesions. A detailed breast specific history was taken including menstrual history, history of mastalgia, lactational history, past and family history of any breast problem. Results showed that, highest incidence of breast lesions was found in the age group of 20-29 years containing (36%) of all cases. The second peak was seen in the age group of 40-49 years containing (18%) of all cases. Left sided lesions were slightly more common. While it was observed that of the 50 cases referred ultrasound correctly diagnosed 42% cases as malignant as compared to 18 % diagnosed as malignant by histopathology. The findings of the study potray that Ultrasound (US) should be used as the initial examination in patients and shall also be used as adjuvant to mammography in older patients.
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    Hepatic involvement in tropical pulmonary eosinophilia.
    (1984-05-01) Jain, A P; Khan, N; Gupta, O P; Jajoo, U N
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    High resolution ultrasound of ophthalmic patients in a tertiary hospital.
    (2007-01-09) Hossain, G A; Islam, S M; Mahmood, S; Khan, N; Chakraborty, R K; Talukder, A K
    The study was done to find out pathologic processes in ophthalmic patients in different age group to understand the use, role and limitations of ultrasonography in the diagnosis of ocular pathology in this locality. A prospective study was done on total 143 patients from September 2004 to January 2006 who attended Centre for Nuclear Medicine & Ultrasound, Mymensingh for ultrasound evaluation of eye. Total 100 (69.93%, n=100) cases were male and 43 (30.06%, n=43) cases were female. The age ranges were 2 months to 80 years. A variety of ocular pathology was diagnosed with the help of high resolution ultrasound (HRUS) with unique ultrasound appearance. Bulk of the referral patients had history of ocular trauma (38.46 %, n= 38) and most commonly detected pathology in these group are vitreous hemorrhage (34.44%, n=34) and cataract formation (28.28%, n=28). Almost all of the patients did not have conclusive diagnosis clinically and by conventional means available before ultrasonography were performed. High resolution sonography may be used as a valuable tool for evaluation of ophthalmic pathology as a well suited, noninvasive method, and only practical imaging modality for assessing those cases particularly when light conducting media are opaque.
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    Immunopathology of skin lesions.
    (2001-09-01) Khan, N; Maheshwari, V; Trivedi, I; Kalam, A
    A study was conducted on 130 patients suffering from skin lesions which included psoriasis, lichen planus, DLE, pemphigus, vitiligo and alopecia areata. Forty age-and-sex-matched healthy individuals served as control. Serum IgG, IgM, and circulating immune complexes (CIC) were estimated. Significant increase in serum IgG (1937.2 +/- 1030.43 mg%) and IgM (232.12 +/- 136.98 mg%) was observed in all the skin lesions when compared with controls except in lichen planus where they were significantly lowered, values being 580.61+/- 77.35 mg% and 66.88 +/- 6.59 mg% respectively. CIC levels were significantly raised (P< 0.00 1) in various skin lesions (40.49+/-23.29) when compared with controls (17.68+/- 3.21), but no significance was observed in lichen planus( 17.72 +/- 4.28). Serum IgG, IgM and CIC were statistically significantly altered depending on the extent of the lesion and lowered significantly to almost normal values following treatment, thereby confirming the role of immunity in the pathogenesis of these skin disorders.
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    Incidence of bony secondary at presentation of breast carcinoma in our region.
    (2003-01-29) Islam, S M; Mahmood, S; Hossain, G A; Khan, N; Chakraborty, R K; Uddin, K; Islam, A; Rahman, M
    Study is conducted to evaluate the incidence of bony secondary and to evaluate the need for routine bone scintigraphy at the time of presentation of breast carcinoma in this region. Of the total 130 patients evaluated by bone scan, sixty (n = 60, 46.15%) had secondary lesion in bone. Among the 54 preoperative patients, all with positive FNAC, twenty (n = 20, 37.03%) had bony metastases. Of the 76 post-operative patients, forty (n = 40, 52.63%) had secondary bone lesions. Single lesion was seen in only five (n = 5, 8.53%) cases. Rest fifty five (n = 55, 91.67%) had multiple bony secondaries. Most of the postoperative cases (n = 40, 52.63%) were invasive/infiltrative duct cell carcinoma. The very high incidence of bony secondary appears to be due to delayed presentation associated with poor socioeconomic condition, ignorance and also shyness. Bony metastases at the time of presentation suggests poor prognosis. As it can affect therapeutic management of these patients, routine bone scintigraphy at the time of presentation of breast carcinoma patients to a tertiary label hospital is proposed, against conflicting conclusion by papers in the developed countries.
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    Mathematical Analysis of Side effects of HIV/AIDS Medication.
    (2014-04) Tirmizi, S R H; Khan, N
    Acquired Immune deficiency syndrome (AIDS) is caused by Human immunodeficiency virus (HIV); More than 40 Million people live with HIV world wide. Various antiretroviral classes of drugs are used to treat HIV infection and the prolonged treatment has to be taken for the rest of life. It is very difficult to continue prolonged treatment because of problem of adherence and side effects. The basic purpose of antiretroviral treatment is to maintain the quality of life of a patient. However, these side effects vary from drug to drug and patient to patient. The objective of this research is to be modeled some major drug induced side effects by using fuzzy matrix theory which is one of the best tools to analyze unsupervised data involving imprecision. This study is of interest for HIV Specialist and physician who care for HIV/AIDS patients with an aim to concentrate more on safety profile of HIV/AIDS drugs
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    Performance of Integrated Nutrient Management and Foliar Spray of Micronutrients on Growth, Yield Attribute and Yield of Wheat (Triticum aestivum L.)
    (Ms. M. B. Mondal, 2023-11) Kumar, R; Siddiqui, MZ; Teotia, V; Dhanker, A; Naresh, R; Khan, N; Suryabhan
    A field experiment was conducted during two rabi seasons of 2021-2022 and 2022-23 at Students’ Instructional Farm of Chandra Shekhar Azad University of Agriculture and Technology Kanpur, (U.P.) The experiment was caried out in SPD (Split Plot Design) with fifteen treatment combination were replication thrice. fifteen treatment treatments combination consisted of three organic manure + RDF nutrient source (Control (100% RDF), 100 % RDF + Vermicompost @ 2.5t/ha, and 100 % RDF + FYM @ 5t/ha) put under main plot and five foliar spray of micronutrient control (No spray),Foliar spray of ZnSO4 @ 0.25% at tillering and booting stages, Foliar spray of Nano Zinc @ 0.5% at tillering and booting stages, Foliar spray of FeSO4 @ 0.25% at tillering and booting stages and M5- Foliar spray of ZnSO4 @ 0.25% + FeSO4 @ 0.25% at tillering and booting stages) allotted under sub plot. The study on yield attribute and yield of wheat. The result showed that the maximum increase growth parameters, yield attribute and yield of wheat viz plant height (cm), number of tillers/m2, and leaf area index and number of grain/spike, number spike/m2, total grain weight spike (g) and test weight (1000 grain weight) (g) and grain yield (t/ha) and straw yield (t/ha) recorded significantly higher with F2- 100 % RDF + Vermicompost @ 2.5t/ha treatments. Among the sub plot, M5- foliar spray of ZnSO4 @ 0.25% + FeSO4 @ 0.25% at tillering and booting stages produced significantly maximum highest grain yield (5.95 t/ha) and straw yield (7.94 t/ha)
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    Platelet auto-antibodies in septicaemic patients.
    (1999-01-27) Ghosh, T K; Khan, N; Malik, A
    Thrombocytopenia associated with acute Septicaemia has been reported which may be due to Disseminated Intravasscular Coagulation (DIC), but has also been reported even without any evidence of it. An immunological cause has been suggested to explain this observation. The present study involved the investigation of 50 patients with clinical and bacteriological evidence of Septicaemia. By Direct Platelet Suspension Immunofluorescence Test (PSIFT) antiplatelet antibodies were detected in 54% patients with septicaemia and 67.5% with those having thrombocytopenia. The septicaemic patients were treated with antibiotics (mean 14 days). After successful treatment, i.e., when there was no bacteriological evidence of septicaemia, there was in increase in the platelet count (> 150 x 10(9)/L) with a corresponding fall in "PSIFT" positivity in 17 cases (P < 0.001). Hence an immunological process is considered to play a significant role in the pathogenesis of thrombocytopenia in these patients with septicaemia.