IMSEAR Repository :: Browsing by Author "Kanga, A"

Browsing by Author "Kanga, A"

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Antimicrobial resistance pattern and in vivo activity of azithromycin in Salmonella isolates.
(2013-07) Garg, A; Verma, S; Kanga, A; Singh, D; Singh, B
We evaluated antimicrobial susceptibility pattern of 42 Salmonella isolates from February 2012 through January 2013. We also determined the minimum inhibitory concentrations (MICs) of azithromycin against Salmonella isolates and compared them with corresponding disc diffusion sizes. Entire 42 isolates were sensitive to chloramphenicol, 41 (97.6%) were sensitive to cotrimoxazole and amoxicillin each. MICs for azithromycin ranged from 2 μg/ml to 24 μg/ml, corresponding zone diameters ranged from 15 mm to 33 mm and the two were significantly correlated (P = 0.001). Our results indicate that whereas, azithromycin is a potential therapeutic option, the sensitivity to the first line drugs and absence of multidrug resistance reinforce the concept of antimicrobial recycling.
Blood stream infection by Chryseobacterium species in an immunocompetent individual.
(2016-01) Sharma, P; Gupta, S; Verma, S; Singh, D V; Kanga, A
A case of human thelaziasis from Himachal Pradesh.
(2006-01-01) Sharma, A; Pandey, M; Sharma, V; Kanga, A; Gupta, M L
Small, chalky-white, threadlike, motile worms were isolated from the conjunctival sac of a 32 year-old woman residing in the Himalaya mountains. They were identified as both male and female worms of Thelazia callipaeda. To the best of our knowledge, this is the second case report of human thelaziasis from India.
Current spectrum of oculomycosis in North India: A 5‑year retrospective evaluation of clinical and microbiological profile.
(2016-01) Verma, S; Sharma, V; Kanga, A; Sharma, R; Angrup, A; Mokta, K; Garg, A
Oculomycosis is a major cause of visual impairment. Eye pain, redness, discharge, diminution and photophobia are presenting features. We collected corneal scraping, vitreous, aqueous fluids and conjunctival swabs after the slit‑lamp examination. Ophthalmological findings were hypopyon, stromal congestion, conjunctival congestion and epithelial defect. Direct microscopy of 10% potassium hydroxide (KOH) wet mounts, gram staining, fungal and bacterial cultures were performed. Fungal isolates were obtained in 24% patients with equal number of both sexes and average age 49 years. KOH revealed fungi in 73% samples and 43.33% were positive on Gram staining. Fusarium spp. (36.66%), Aspergillus spp. (23.33%) and melanised fungi (20%) were common etiological agents. Fusarium spp. was more often associated with complications. Trauma was a predisposing factor in 65% cases and occurred mainly with vegetable matter. The majority responded to the conservative management with 5% natamycin and four patients required surgery.
Emerging Salmonella Paratyphi A enteric fever and changing trends in antimicrobial resistance pattern of salmonella in Shimla.
(2010-01) Verma, S; Thakur, S; Kanga, A; Singh, G; Gupta, P
This retrospective study incorporates a six years, six months (January 2000-June 2006) laboratory data comprising 258 isolates of Salmonella. Cultures were identified by standard methods. Salmonella enterica serotype Typhi (S.Typhi) was the more frequent serotype isolated i.e., 61.62% with the remaining 38.37% being Salmonella enterica serotype Paratyphi A (S. Paratyphi A). There was emergence of S. Paratyphi A as the predominant serotype in 2003-2004 with resurgence of serotype Typhi thereon. A total of 66.27% isolates were resistant to one or more antibiotics. MDR S. Typhi was 10.69% and while 13.13% were MDR S. Paratyphi A. There was decrease in resistance to ampicillin, cotrimoxazole in 2004 and nalidixic acid beyond 2005 and increase in resistance to cefuroxime. We also documented a decrease in resistance to ciprofloxacin after 2005.
Incidence of cryptosporidiosis in children with acute and persistent diarrhoea in and around Shimla.
(1997-03-01) Goyal, A; Thakur, R; Singh, T; Kanga, A; Sharma, V
Invasive aspergillosis involving multiple paranasal sinuses--a case report.
(2005-07-16) Agarwal, S; Kanga, A; Sharma, V; Sharma, D R; Sharma, M L
A case of invasive multiple paranasal sinus aspergillosis with bony involvement is reported. A young immunocompetent lady presented with bilateral nasal obstruction due to polyps. Radiologically and histopathologically a fungal cause was kept a possibility, and the diagnosis of Aspegillus fumigatus was established by demonstration of acute angle branching septate hyphae on direct wet mount and repeated isolation in culture. Patient responded favourably to surgical excision of polyps and oral itraconazole post operatively.
Keratitis by Paecilomyces lilacinus: A case report from Sub‑Himalayan region.
(2015-10) Sharma, V; Angrup, A; Panwar, P; Verma, S; Singh, D; Kanga, A
Paecilomyces lilacinus is a filamentous fungus found in soil and air, which is a rare cause of ocular infection. The majority of case reports involving P. lilacinus among healthy hosts are of endophthalmitis and keratitis. We report a rare case of keratomycosis by P. lilacinus, in an immunocompetent, which responded well to treatment with ketoconazole. Some species belonging to the genus Paecilomyces such as P. lilacinus generally shows a poor response to conventional antifungal drugs. Therefore, correct identification of clinical isolates to the species level is mandatory for the appropriate treatment of the disease.
Outbreak of enteric fever due to Salmonella Paratyphi A variety durazzo (2,12:a:‑) in a hilly region of North India: A report of 43 cases.
(2016-07) Verma, S; Sharma, V; Mokta, K; Thakur, C; Angrup, A; Singh, D; Kanga, A
Enteric fever due to Salmonella Paratyphi A (SPA) is a global problem occurring as outbreaks at times. An unusual SPA (2,12:a:‑) variety durazzo has been reported rarely. We report an outbreak of enteric fever due to this variety affecting 43 individuals. The blood samples grew unusual mucoid, lactose non‑fermenting colonies with atypical biochemical reactions in sugar fermentation and amino acid decarboxylation. Isolates had sensitivity to ceftriaxone, chloramphenical, cotrimoxazole, intermediate susceptibility to ciprofloxacin and resistance to ampicillin and nalidixic acid. Identification was confirmed as SPA (2,12:a:‑) at the National Salmonella Centre.
Primary thoracic wall tuberculosis: A rare case.
(2015-02) Sharma, P; Mehta, V K; Guleria, R C; Singh, D; Kanga, A; Mohindroo, S
Relevance of Weil-Felix test in diagnosis of scrub typhus in India.
(2006-08-01) Mahajan, S K; Kashyap, R; Kanga, A; Sharma, V; Prasher, B S; Pal, L S
OBJECTIVE: To study the relationship of Weil-Felix test and microimmunofluorescence test. METHODS: Sera of 21 patients with clinical diagnosis of scrub typhus were subjected to Weil-Felix and Microimmunofluorescence tests. RESULTS: On Weil-Felix test, 13 (62%) sera showed titers 1: > or = 40-320. 7 patients showed titers 1: > or = 320, 3 showed titers 1 : 160, 2 showed titers 1 : 80 and 1 patients showed titers 1 : 40, to Proteus OXK antigen. All 21 sera showed significant titers to O. tsutsugamushi on microimmunofluorescence. CONCLUSION: Weil-Felix test is not a very sensitive test in diagnosis of scrub typhus but due to of lack of availability of definitive tests in India it canbe a useful tool when used and interpreted in the correct clinical context.
Tuberculous duodenal obstruction--a case report.
(1997-06-01) Thakur, S; Minhas, S S; Kanga, A; Sharma, V
Proximal duodenal obstruction due to tuberculosis can masquarade as duodenal ulcer. Although commonest cause of duodenal obstruction is ulcer, other causes must be considered, particularly tuberculosis which is common in tropics.

Browsing by Author "Kanga, A"

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