Browsing by Author "Kabi, B C"
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Item Brain cholesterol and phospholipid levels in cyproheptadine treated albino rats.(1993-04-01) Kabi, B C; Rao, Y N; Parsi, B; Chakrabarty, A SEffect of different doses (2.5 mg, 5 mg, 10 mg and 40 mg/kg), s.c., for 2 weeks, of cyproheptadine (CYP) on brain cholesterol and phospholipid of albino rats was investigated. Cyp. 2.5 mg/kg, showed increase in brain cholesterol and phospholipid contents whereas other doses caused a decrease in phospholipid level.Item Levels of erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, G6PD activity & plasma urate in patients of pregnancy induced hypertension.(1994-07-01) Kabi, B C; Goel, N; Rao, Y N; Tripathy, R; Tempe, A; Thakur, A STo assess the oxidative stress across the cell membrane in patients suffering from pregnancy induced hypertension, erythrocyte malonyldialdehyde, vitamin E, reduced glutathione, glucose-6-phosphate dehydrogenase activity and plasma urate levels were estimated in 25 non pregnant women, 40 normotensive pregnant women and 40 women with pregnancy induced hypertension (PIH). As compared to non pregnant women, there was a significant increase in the levels of erythrocyte malonyldialdehyde and plasma urate in normotensive pregnant women, which were further increased in women with PIH. Erythrocyte glutathione levels were raised in normotensive pregnant women as compared to non pregnant women. Its levels were decreased in patients of PIH as compared to normotensive pregnant women. Cellular bio-availability of vitamin E was depressed in both normotensive pregnancy as well as patients with pregnancy induced hypertension as compared to non pregnant women.Item Localization of mycobacteral smegmatis adenosine deaminase.(2010-11) Thakur, A S; Rao, Y N; Kabi, B C; Sharma, U; Khan, Y JThe study was carried out to check the localization of M.smegmatic adenosine deaminase for its metabolic and clinical importance. The separation and washing of the membrane was done by using refrigerated high-speed centrifuge. The high activity was observed in crude extract while low activity in first washing of the membrane but after second washing there was no enzyme activity seen. Culture media also does not show any enzyme activity. Thus M.smegmatic adenosine deaminase may be a cytosolic enzyme and it does not excreted in to the surrounding media.Item Polycystic ovarian syndrome and insulin resistance: a North Indian study.(2015-06) Agarwal, Nitin; Gangopadhyay, Sukanya; Koch, Nirensingh; Gupta, Akash; Batra, Aruna; Kabi, B CBackground: Polycystic ovarian syndrome (PCOS) is most common form of chronic anovulation associated with androgen excess. Insulin resistance (IR) is characterized by impaired glucose response to specific amount of insulin. The objective of the study was to find an association between PCOS and IR in North Indian patients. Methods: A total of 50 PCOS cases diagnosed according to Rotterdam criteria, 2003, i.e. at least two of the following three features: oligomenorrhea or amenorrhea, clinical or biochemical hyperandrogenism and polycystic ovaries on ultrasound. Serum glucose levels were measured spectrophotometrically by glucose oxidase-peroxidase method. Insulin levels in serum were estimated by using ELISA based kit procured form Diasorin Ltd, Germany. Homeostatic Model Assessment- Insulin Resistance (HOMA-IR) and Body Mass Index (BMI) were calculated by their formulas. Results: PCOS patients had significantly higher values of BMI, fasting serum glucose, fasting serum insulin and HOMA-IR. Fasting serum glucose was however in the normal range in both cases and control. Conclusion: Our study suggested a strong association of PCOS with insulin resistance in this part of the country.Item Renal lipids in cyproheptadine treated albino rats.(1996-01-01) Kabi, B C; Rao, Y N; Parsi, B; Chakrabarty, A SItem Serum triglyceride and lipoprotein cholesterol in male survivor of ischaemic heart disease in eastern Uttar Pradesh (north India).(1985-05-01) Kabi, B C; Somani, P N; Koteswara Rao, G RItem Urinary calcium creatinine ratio and hypercalciuria.(1994-03-01) Rath, B; Aggarwal, M K; Mishra, T K; Talukdar, B; Murthy, N S; Kabi, B CRandom urine samples of 352 children in the age group of 5-12 yrs were studied for urinary calcium-creatinine ratio (Uca/Ucr mg/mg). None had any predisposing factor for secondary hypercalciuria. Calcium and creatinine both were estimated by colorimetric method. We observed that Uca/Ucr in the general pediatric population was skewed, the pattern was similar to that described in western children and it was independent of age and sex. The mean and standard deviation (SD) of Uca/Ucr was 0.10 +/- 0.094. Considering mean +2SD as the upper limit of normal, which was 0.29 in this series, the prevalence of hypercalciuria was 6.5%.